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A retrospective multicenter study of carbon‐ion radiotherapy for major salivary gland carcinomas: Subanalysis of J‐CROS 1402 HN

Cancer Science, 2018
A retrospective multicenter study was conducted to assess the clinical outcomes of carbon-ion radiotherapy for head and neck malignancies (Japan Carbon-Ion Radiation Oncology Study Group [J-CROS] study: 1402 HN).
Kazuhiko Hayashi, Masashi Koto, Yusuke Demizu   +2 more
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Clinical Indications for Carbon Ion Radiotherapy

Clinical Oncology, 2018
Compared with photon and proton therapy, carbon ion radiotherapy (CIRT) offers potentially superior dose distributions, which may permit dose escalation with the potential for improved sparing of adjacent normal tissues. CIRT has increased biological effectiveness leading to increased tumour killing compared with other radiation modalities.
Mohamad, O., Yamada, S., Durante, M.
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Radiotherapy with beams of carbon ions

Reports on Progress in Physics, 2005
In cancer treatment, the introduction of MeV bremsstrahlung photons has been instrumental in delivering higher doses to deep-seated tumours, while reducing the doses absorbed by the surrounding healthy tissues. Beams of protons and carbon ions have a much more favourable dose-depth distribution than photons (called ‘x-rays’ by medical doctors) and are ...
Ugo Amaldi, Gerhard Kraft
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Carbon Ion Radiotherapy for Unresectable Retroperitoneal Sarcomas

International Journal of Radiation Oncology*Biology*Physics, 2009
To evaluate the applicability of carbon ion radiotherapy (CIRT) for unresectable retroperitoneal sarcomas with regard to normal tissue morbidity and local tumor control.From May 1997 to February 2006, 24 patients (17 male and 7 female) with unresectable retroperitoneal sarcoma received CIRT. Age ranged from 16 to 77 years (median, 48.6 years).
Itsuko, Serizawa, Kenji, Kagei, Tadashi, Kamada, Reiko, Imai, Shinji, Sugahara, Tohru, Okada, Hiroshi, Tsuji, Hisao, Ito, Hirohiko, Tsujii   +8 more
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Carbon Ion Radiotherapy in the Treatment of Pancreatic Cancer

Pancreas, 2020
Abstract Pancreatic cancer is the fourth most common cause of cancer-related morality worldwide, and the prognosis remains poor despite aggressive therapy. Carbon ion radiotherapy has favorable radiobiological and physical characteristics in the treatment, including a higher linear energy transfer and higher relative biological effectiveness,
Timothy D, Malouff, Sunil, Krishnan, Christopher L, Hallemeier, Michael G, Haddock, Bradford S, Hoppe, Chris, Beltran, Anita, Mahajan, Daniel M, Trifiletti   +7 more
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Carbon ion radiotherapy in the treatment of gliomas: a review

Journal of Neuro-Oncology, 2019
Gliomas are among the most common primary brain malignancies, with a poor prognosis for high grade gliomas despite aggressive therapy. Carbon ions, which exhibit favorable biological and physical characteristics, have recently been studied in intracranial malignancies as a way to escalate dose to the tumor while minimizing dose to normal tissue.Pubmed ...
Timothy D. Malouff, Jennifer L. Peterson, Anita Mahajan, Daniel M. Trifiletti   +3 more
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Results of carbon ion radiotherapy in 152 patients

International Journal of Radiation Oncology*Biology*Physics, 2004
This study summarizes the experience with raster scanned carbon ion radiation therapy (RT) at the Gesellschaft für Schwerionenforschung (GSI), Darmstadt, Germany since 1997.Between December 1997 and December 2002, 152 patients were treated at GSI with carbon ion RT.
Daniela, Schulz-Ertner, Anna, Nikoghosyan, Christoph, Thilmann, Thomas, Haberer, Oliver, Jäkel, Christian, Karger, Gerhard, Kraft, Michael, Wannenmacher, Jürgen, Debus   +8 more
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Carbon ion radiotherapy of skull base chondrosarcomas

International Journal of Radiation Oncology*Biology*Physics, 2007
To evaluate the effectiveness and toxicity of carbon ion radiotherapy in chondrosarcomas of the skull base.Between November 1998 and September 2005, 54 patients with low-grade and intermediate-grade chondrosarcomas of the skull base have been treated with carbon ion radiation therapy (RT) using the raster scan technique at the Gesellschaft für ...
Daniela, Schulz-Ertner, Anna, Nikoghosyan, Holger, Hof, Bernd, Didinger, Stephanie E, Combs, Oliver, Jäkel, Christian P, Karger, Lutz, Edler, Jürgen, Debus   +8 more
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Workflow of Carbon-Ion Radiotherapy

2013
The carbon-ion radiotherapy system consists of oncology information system (OIS), radiotherapy treatment planning system (RTPS), and beam delivery system (BDS), which is similar to the standard radiotherapy system. However, there are some differences, such as a big accelerator system, no gantry system (except HIT), and an efficient workflow system. The
Toshiyuki Shirai, Yuka Takei
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The Characteristics of Carbon-Ion Radiotherapy

2013
The fundamental principle of radiotherapy lies in precise dose delivery to the target, while minimizing damage to the surrounding normal organs. Carbon ion beams have a definite range and sharp high-dose Bragg peak. At the carbon ion Bragg peak, the ionization is enormous and shows high biological effects.
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