Out-of-beam artifact suppression in charged nuclear fragment based carbon-ion radiotherapy monitoring. [PDF]
Kirchgässner R +7 more
europepmc +1 more source
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini +9 more
wiley +1 more source
Industrial Hydrocarbons Exposure Deteriorates Sperm Integrity and Reproductive Function
ABSTRACT Occupational exposure to polycyclic aromatic hydrocarbons (PAHs) or metal fumes in the workplace may be detrimental to male fertility. The present study compared sperm concentration, total motility, strict morphology and oxidative stress and SDF levels between 81 men, controls (n = 17) and workers from plastic industry workers (n = 18), steel ...
Madhan Kumar Pichandi +2 more
wiley +1 more source
Factors requiring adaptive re-planning in carbon ion radiotherapy for head and neck cancers. [PDF]
Yamada T +6 more
europepmc +1 more source
Audiovestibular Outcomes After Parathyroidectomy in Primary Hyperparathyroidism
ABSTRACT Objective To prospectively evaluate audiovestibular outcomes following parathyroidectomy in patients with primary hyperparathyroidism (pHPT) using a comprehensive battery of audiological, vestibular, and patient‐reported outcome measures. Methods This prospective observational study included 31 adult patients undergoing parathyroidectomy for ...
Erdem Köroğlu +3 more
wiley +1 more source
Evaluation and implementation of an independent Kilovoltage X-ray-based imaging platform for carbon ion radiotherapy. [PDF]
Guo Y +7 more
europepmc +1 more source
Radiotherapy‐induced xerostomia severely impairs quality of life. Integrated multiomics, organoids, murine models, and a randomized Phase II trial identified spermidine as a key radiation‐responsive metabolite. Oral spermidine preserved salivary gland function, maintained acinar cell integrity through Golgi‐mediated posttranslational modifications ...
Yu Min +4 more
wiley +1 more source
Commissioning and robustness evaluation of external laser sensor for respiratory gating in carbon-ion radiotherapy. [PDF]
Kim TH +9 more
europepmc +1 more source
Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives
The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng +9 more
wiley +1 more source
Carbon Ion Radiotherapy for Retroperitoneal Sarcoma: A Single-Institution Study. [PDF]
Imai R +6 more
europepmc +1 more source

