Phase Ib/II trial to evaluate the safety and efficacy of atezolizumab and bevacizumab as adjuvant therapy following carbon-ion radiotherapy in hepatocellular carcinoma (VANGUARD): study protocol. [PDF]
Koroki K +33 more
europepmc +1 more source
ABSTRACT Esophageal cancer is the seventh leading cause of cancer death, and the energy depletion in cancer cells can be achieved through synergistic therapy. The integration of sonodynamic therapy and chemotherapy offers a promising comprehensive treatment strategy for esophageal cancer.
Mengya Li +4 more
wiley +1 more source
BCOR-CCNB3 fusion-positive sarcoma treated with chemotherapy and carbon-ion radiotherapy: a case report of long-term disease control of a cervical spine case with a 12-year follow-up. [PDF]
Oike N +8 more
europepmc +1 more source
Metal‐Based Materials for Redox Modulation in Biomedicine
ABSTRACT Metal materials have become increasingly important in modulating biological redox networks for therapeutic and diagnostic purposes, owing to their distinctive electronic properties and adaptable reactivity. This review synthesizes recent developments across various metal‐based materials, including elemental metals, metal oxides, coordination ...
Yan Fan +7 more
wiley +1 more source
Development and validation of NTCP models for predicting acute esophagitis in carbon ion radiotherapy for thoracic malignancies. [PDF]
Li Y +6 more
europepmc +1 more source
Peptide‐based responsive molecular fluorescent probes for precision oncology
Peptide‐based responsive fluorescent probes have emerged as adaptive functional materials for precision tumor theranostics, combining tumor‐selective recognition, programmable stimulus responsiveness, and modular tunability. They enable high‐contrast imaging, intraoperative guidance, real‐time monitoring, and multimodal applications, while next ...
Xing Wang +6 more
wiley +1 more source
Evaluation of Magnetic Resonance Imaging-Derived Synthetic Computed Tomography in Prostate Cancer Carbon Ion Radiotherapy: Impact of Fixation Shell. [PDF]
Ishizawa M +6 more
europepmc +1 more source
Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer +11 more
wiley +1 more source
AI-based prediction of recurrence after carbon ion radiotherapy for early stage non-small cell lung cancer. [PDF]
Miyasaka Y +6 more
europepmc +1 more source
Clinical advantages of carbon-ion radiotherapy
Carbon-ion radiotherapy(C-ion RT)possesses physical and biological advantages. It was started at NIRS in 1994 using the Heavy Ion Medical Accelerator in Chiba(HIMAC); since then more than 50 protocol studies have been conducted on almost 4000 patients with avariety of tumors.
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