Results 181 to 190 of about 47,659 (268)
Mutation of Surface Histidines in \u3ci\u3eHaemophilus influenzae\u3c/i\u3e Carbonic Anhydrase to Enable Purification by Metal Affinity Chromatography [PDF]
Cornely, Kathleen, Scola, Shelby E.
core +1 more source
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei +10 more
wiley +1 more source
Abstract Objective Sialidosis type I (ST‐1) is an autosomal‐recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic–clonic seizures (BTCS), and distinctive ophthalmological findings.
Janina Gburek‐Augustat +15 more
wiley +1 more source
Trial sequential analysis suggested the potential overestimated effect of carbonic anhydrase inhibitor for respiratory failure and metabolic alkalosis. [PDF]
Luo MS, Li HZ, Huang GJ, Wu L.
europepmc +1 more source
Halopithys incurva is a red macroalga distributed across the Mediterranean Sea and North‐East Atlantic, with occasional reports from the Indian Ocean. It exhibits a rich chemical diversity, including isoflavones, bromophenols, MAAs, pigments, phycobiliproteins, primary metabolites, and neuroactive compounds.
Youssra Aalilou +9 more
wiley +1 more source
Abstract Neurotoxicity is a common and potentially life‐threatening complication after chimeric antigen receptor T‐cell therapy (CART) for pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). The only consistently demonstrated clinical risk factor for severe neurotoxicity in prior studies is high, preinfusion bone marrow disease burden (DB).
Caroline Diorio +18 more
wiley +1 more source
Abstract Infants and children with KMT2A::AFF1+ leukemia have a dismal prognosis and are therefore in urgent need for more efficient and less aggressive therapy. In this study, we investigated three microRNAs that are downregulated in KMT2A::AFF1+ B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL): miR‐194, miR‐99b, and miR‐125a‐5p.
Camille Malouf +13 more
wiley +1 more source
Carbonic anhydrase inhibitors:
Derya Ekinci +4 more
openaire +1 more source
Population Pharmacokinetic Modeling of Intravenous Topiramate in Patients with Epilepsy or Migraine
Abstract Topiramate (TPM) is approved for seizures and migraine prophylaxis and is used off‐label for several neuropsychiatric conditions. The available dosage forms, including tablets and sprinkle capsules, are unsuitable for patients who may be unable to take medicine orally.
Adeboye O. Bamgboye +7 more
wiley +1 more source
Proteomic profiling of tissue explant‐ and plasma‐derived extracellular vesicles identified colon adenocarcinoma‐associated and healthy‐associated EV proteins. A 10‐protein EV panel enabled highly sensitive blood‐based detection of colon adenocarcinoma, showed marked postoperative changes, and retained performance in an independent validation cohort ...
Yura Seo +33 more
wiley +1 more source

