Results 181 to 190 of about 674,558 (235)

Carbonic Anhydrase I and II as Biomarkers and Therapeutic Targets in Human Disease: From Physiology to Clinical Translation. [PDF]

Int J Mol Sci
Sümer A, Şahin S, Menteşe A.
europepmc   +1 more source

Advances in Organic Aggregates for Biomedical Phototheranostics

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Organic aggregates offer aggregation‐regulated photophysical properties for biomedical phototheranostics, enabling enhanced fluorescence, stabilized room‐temperature phosphorescence, and efficient photoacoustic/photothermal responses. This review highlights molecular design strategies, excited‐state energy modulation, biomedical applications, and ...
Bowen Fu, Yayun Peng, Ting Cai
wiley   +1 more source

Discovery of indolylchalcone benzenesulfonamides as selective inhibitors of tumor-associated carbonic anhydrase IX and XII. [PDF]

Sci Rep
Lee J, Biernacki K, Giovannuzzi S, Nada H, C Rivonker S, Kim C, Supuran CT, Elkamhawy A, Lee K.   +8 more
europepmc   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, Volume 2, Issue 3, Page 498-521, September 2026.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

Med Research, Volume 2, Issue 3, Page 484-497, September 2026.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang, Fen Yang, Xingji Lian, Jie He, Shuijin Huang, Mingjuan Fan, Yin Liang, Jiaqiang Huang, LongYan Yin, Hong Wang   +9 more
wiley   +1 more source

Investigating the Inhibitory Properties of Diazo and Pyrazole-Carboxamide-Linked Benzenesulfonamides Against Carbonic Anhydrase Isoforms I, II, IX, and XII. [PDF]

ChemMedChem
Akocak S, Lolak N, Ammara A, Gürbüz G, Bozgeyik I, Taşdemir D, Hashem H, Bräse S, Supuran CT.   +8 more
europepmc   +1 more source

Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice. [PDF]

Int J Mol Sci, 2017
Noma N, Fujii G, Miyamoto S, Komiya M, Nakanishi R, Shimura M, Tanuma SI, Mutoh M.   +7 more
europepmc   +1 more source

Comprehensive Chemical and Biological Assessment of Orobanche racemosa Extracts Using Chromatographic, In Vitro, In Silico, and Cell‐Based Techniques

ChemistryOpen, Volume 15, Issue 9, September 2026.
Orobanche racemosa can be considered an effective source of natural bioactive agents in designing functional applications. The growing interest in natural product research as a safer and sustainable alternative to synthetic drugs has triggered this study, which evaluates the chemical profile and biological activity of Orobanche racemosa extracts.
Nilofar Nilofar, Enver Saka, Mehmet Veysi Cetiz, Maria J. Rodrigues, Eliana Fernandes, Luisa Custodio, Evren Yildiztugay, Ismail Yapıcı, Ilhami Gulcin, Esraa A. Elhawary, Omayma A. Eldahshan, Abdel Nasser B. Singab, Carlos L. Cespedes‐Acuna, Gokhan Zengin   +13 more
wiley   +1 more source

Metabolite-Driven Biological Activity of Mandragora autumnalis and Spartium junceum: A Comparative LC-MS/MS Study on Antioxidant, Cholinesterase, and Carbonic Anhydrase Inhibition. [PDF]

ChemistryOpen
Aslan K, Elbir E, Bicakci Y, Ozdogan S, Yilmaz MA, Gulcin I.   +5 more
europepmc   +1 more source

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy, Emmanuel Anyachukwu Irondi, Abdulazeez Olamilekan Elemosho, Emmanuel Oladipo Ajani   +3 more
wiley   +1 more source