Computergestützte Leitstruktursuchen in Moleküldatenbanken am Beispiel der humanen Carboanhydrase II [PDF]
Grüneberg, Sven, Prof. Dr. G. Klebe
core +1 more source
Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee +6 more
wiley +1 more source
Click Chemistry-Enabled Parallel Synthesis of N-Acyl Sulfonamides and Their Evaluation as Carbonic Anhydrase Inhibitors. [PDF]
Gavrylenko OV +14 more
europepmc +1 more source
Biological Templates for Gold Nanocluster Assembly: Design and Biomedical Applications
The review discusses the fundamental properties of ultrasmall gold nanoclusters and their surface modification strategies for targeted biomedical use. It examines biologically guided assembly processes and their effects on optical behavior, particularly aggregation‐induced emission.
Zeineb Ayed +3 more
wiley +1 more source
Retrospective Assessment of Carbonic Anhydrase Inhibitors in Topical or Episcleral Implant Form for the Treatment of Equine Glaucoma. [PDF]
Tucker-Retter EK +3 more
europepmc +1 more source
Benzoxaboroles Are Inhibitors of the η‐Class Carbonic Anhydrase From Plasmodium falciparum
Benzoxaborole‐based inhibitors demonstrate potent, low‐micromolar inhibition of the essential malaria target PfaCA and are effective in vitro suppression of P. falciparum. Molecular docking confirms target engagement via zinc coordination, establishing this chemotype as a promising scaffold for the development of next‐generation antimalarials ...
Alessandro Bonardi +9 more
wiley +1 more source
Carbonic anhydrase inhibitors limit complications in X-linked retinoschisis. [PDF]
Wey S, Brill DA, Miraldi Utz V, Sisk RA.
europepmc +1 more source
Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?
Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley +1 more source
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen +4 more
wiley +1 more source
Hyaluronic Acid-Palmitate Nanoparticle Delivery of Carbonic Anhydrase Inhibitors Impairs Growth and Early Metabolism in Escherichia coli Through β- and γ-Carbonic Anhydrase-Associated Processes. [PDF]
De Luca V +4 more
europepmc +1 more source

