Background & Aims: Human enteroids present a novel tool to study human intestinal ion transport physiology and pathophysiology. The present study describes the contributions of Cl- and HCO3- secretion to total cyclic adenosine monophosphate (cAMP ...
Jianyi Yin+6 more
doaj
To Explore the Potential Inhibitors against Multitarget Proteins of COVID 19 using In Silico Study [PDF]
The global pandemic due to emergence of COVID 19 has created the unrivaled public health crisis. It has huge morbidity rate never comprehended in the recent decades. Researchers have made many efforts to find the optimal solution of this pandemic. Progressively, drug repurposing is an emergent and powerful strategy with saving cost, time, and labor ...
arxiv
Carbonic Anhydrase Inhibitors: Synthesis and Inhibition Against Isozymes I, II and IV of Topically Acting Antiglaucoma Sulfonamides Incorporatingcis-5-Norbornene-endo-3-Carboxy-2-Carboxamido Moieties [PDF]
Angela Casini+5 more
openalex +1 more source
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata+6 more
wiley +1 more source
Carbonic Anhydrase Activity Modulators: Synthesis of Inhibitors and Activators Incorporating 2-substituted-thiazol-4-yl-methyl Scaffolds [PDF]
Andrea Scozzafava+3 more
openalex +1 more source
Carbonic anhydrase inhibitors and osmotic agents in glaucoma. Carbonic anhydrase inhibitors. [PDF]
openaire +3 more sources
How eriophyid mites shape metal metabolism in leaf galls on Tilia cordata
Summary Metal metabolism in plant–galler interactions is largely unknown. We hypothesise that the mites manipulate metal distribution by sequestration of excessive levels and differential regulation of metalloproteins to support the main functions of gall‐nutrition, protection and microenvironment.
Filis Morina+8 more
wiley +1 more source
Design and synthesis of some new benzoylthioureido benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors. [PDF]
Oudah KH+7 more
europepmc +1 more source
Carbonic Anhydrase Inhibitors. Inhibition of Cytosolic Isozymes I and II and Transmembrane, Cancer-associated Isozyme IX with Lipophilic Sulfonamides [PDF]
Marco Franchi+7 more
openalex +1 more source