Crystals, 2021 A set of mesomorphic materials in which the o-carborane cluster is covalently bonded to a cholesteryl benzoate moiety (mesogen group) through a suitably designed linker is described.
Albert Ferrer-Ugalde +6 more
doaj +1 more source
Towards the Application of Purely Inorganic Icosahedral Boron Clusters in Emerging Nanomedicine
Molecules, 2023 Traditionally, drugs were obtained by extraction from medicinal plants, but more recently also by organic synthesis. Today, medicinal chemistry continues to focus on organic compounds and the majority of commercially available drugs are organic molecules,
Francesc Teixidor +2 more
doaj +1 more source
Radioiodination of Two Carborane-Based Dual Cyclooxygenase-2/5-Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation. [PDF]
ChembiochemTwo dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Schädlich J +11 more
europepmc +2 more sources
Synthesis and X-ray characterization of 15- and 16-vertex closo-carboranes
Nature Communications, 2020 The synthesis of closo-carboranes with more than 14 vertexes is challenging, and no examples have been reported to date. Herein, the authors present the long-sought 15- and 16-vertex closo-carboranes, in which the introduction of silyl groups to the two ...
Fangrui Zheng +3 more
doaj +1 more source
Asymmetric 1,8/13,2,x-M2C2B10 14-vertex metallacarboranes by direct electrophilic insertion reactions; the VCD and BHD methods in critical analysis of cage C atom positions [PDF]
, 2014 The isolation of six isomeric, low-symmetry, dicobaltacarboranes with bicapped hexagonal antiprismatic cage structures, always in low yield, is described from reactions in which 13-vertex cobaltacarborane anions and sources of cobalt-containing cations ...
Ellis, David +4 more
core +1 more source
Could humans recognize odor by phonon assisted tunneling? [PDF]
, 2006 Our sense of smell relies on sensitive, selective atomic-scale processes that are initiated when a scent molecule meets specific receptors in the nose. However, the physical mechanisms of detection are not clear.
A. M. Stoneham +16 more
core +2 more sources
Iridium-catalysed regioselective borylation of carboranes via direct B–H activation
Nature Communications, 2017 Functionalization of the multiple, similar, boron-hydrogen bonds in carboranes is difficult to achieve with selectivity. Here the authors report an iridium-catalysed borylation ofo-carboranes with high yields and regioselectivities.
Ruofei Cheng, Zaozao Qiu, Zuowei Xie
doaj +1 more source
The Importance of Strain (Preorganization) in Beryllium Bonds
Molecules, 2020 In order to explore the angular strain role on the ability of Be to form strong beryllium bonds, a theoretical study of the complexes of four beryllium derivatives of orthocloso-carboranes with eight molecules (CO, N2, NCH, CNH, OH2, SH2, NH3, and PH3 ...
Ibon Alkorta +5 more
doaj +1 more source
Synthesis and In Vitro Biological Evaluation of p-Carborane-Based Di-tert-butylphenol Analogs
Molecules, 2023 Targeting inflammatory mediators and related signaling pathways may offer a rational strategy for the treatment of cancer. The incorporation of metabolically stable, sterically demanding, and hydrophobic carboranes in dual cycloxygenase-2 (COX-2)/5 ...
Sebastian Braun +10 more
doaj +1 more source
Geophysical Monograph Series, Page 341-349., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Sulgiye Park, Yu Lin, Wendy L. Mao
wiley +1 more source