Results 211 to 220 of about 213,511 (352)

Histologically verified penile lichen sclerosus—Incidence in Denmark over 26 years and long‐term risk of penile and non‐penile cancer

International Journal of Cancer, EarlyView.
What's New? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk, Emma L. Kaderly Rasmussen, Charlotte Gerd Hannibal, Rasmus Hertzum‐Larsen, Louise Baandrup, Susanne K. Kjær   +5 more
wiley   +1 more source

Limited association between HRR gene alterations and HRD in molecular tumor board cancer samples: Who should be tested for HRD?

International Journal of Cancer, EarlyView.
What's New? Currently, no published data on homologous recombination deficiency (HRD) testing in the setting of molecular tumor boards exist. This study in a cohort of 237 patients encompassing 24 different tumor entities assessed by a molecular tumor board shows that inactivating alterations of BRCA1/2 are not always associated with an elevated ...
Christoph Schubart, Lars Tögel, Maria Giulia Carta, Philip Hetzner, Lina Helbig, Charlotte Zaglas, Maria Ziegler, Robert Stöhr, Annett Hölsken, Juliane Hoyer, Fulvia Ferrazzi, Clemens Neufert, Sebastian Lettmaier, Marianne Pavel, Henriette Golcher, Sarina K. Mueller, Florian Fuchs, Carla E. Schulmeyer, Matthias W. Beckmann, Bernd Wullich, Abbas Agaimy, Andre Reis, Arndt Hartmann, Norbert Meidenbauer, Silvia Spoerl, Florian Haller, Evgeny A. Moskalev   +26 more
wiley   +1 more source

Cytology-Radiology Correlation Series: Pancreatic cytopathology. [PDF]

Cancer Cytopathol
Trieu J, Gilman A, Konstantinoff K, Lozano MD, Saieg M.   +4 more
europepmc   +1 more source

Mitophagy: A novel perspective for insighting into cancer and cancer treatment

Cell Proliferation, Volume 55, Issue 12, December 2022., 2022
Mitophagy is a physiological process regulated by complex and diverse mechanisms. Here we summarize the 15 main molecular mechanisms involved in the mammalian mitophagy processes and some potential anticancer drugs targeting mitophagy. Abstract Background Mitophagy refers to the selective self‐elimination of mitochondria under damaged or certain ...
Congkuan Song, Shize Pan, Jinjin Zhang, Ning Li, Qing Geng   +4 more
wiley   +1 more source

A Rare Case of Ampullary Carcinoma with Complete Duodenal Obstruction as the Initial Manifestation. [PDF]

Surg Case Rep
Kakizaki Y, Sato A, Enomoto Y.
europepmc   +1 more source

The influence of microbiome‐derived amino acids metabolites in shaping the glioma immunosuppressive microenvironment

Interdisciplinary Medicine, EarlyView.
Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma, Zhihao Song, Chenlong Yang, Zijin Zhao, Guodong Tang, Jia You, Chong Zeng, Jun Yang, Qing Liu, Haoyu Li, Wei Huang   +10 more
wiley   +1 more source

Delineation of gastrointestinal tumors biopsies using a fluorescence lifetime imaging optical fiber probe

Journal of Biophotonics, EarlyView.
The efficient discrimination of a hepatic cancer lesion and its surgical margin using autofluorescence lifetime imaging is presented. White light image of the specimen on the left and the augmented image with fluorescence lifetime data on the right.
D. Suraci, E. Baria, L. Tirloni, J. L. Lagarto, S. Buccianti, C. Agostini, S. Pillozzi, L. Antonuzzo, A. Taddei, R. Cicchi   +9 more
wiley   +1 more source

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer

Proceedings of the National Academy of Sciences of the United States of America, 2013
C. Feig, James O. Jones, Matthew Kraman, R. Wells, A. Deonarine, Derek S. Chan, Claire M. Connell, Edward W. Roberts, Qi Zhao, O. Caballero, S. Teichmann, T. Janowitz, D. Jodrell, D. Tuveson, D. Fearon   +14 more
semanticscholar   +1 more source

The Combination of Active‐Targeted Photodynamic Therapy and Photoactivated Chemotherapy for Enhanced Cancer Treatment

Journal of Biophotonics, EarlyView.
Photoactivated chemotherapy (PACT), an oxygen‐independent light‐based therapy, utilizes chemotherapeutic regimens that remain inert until exposed to light, allowing target‐specific activation while minimizing off‐target toxicity. The integration of these techniques has the potential to improve selectivity and yield synergistic cytotoxic effects that ...
Nkune Williams Nkune, Heidi Abrahamse
wiley   +1 more source

Case report: a case of R0 resection in a patient with PD-L1-negative, microsatellite-stabilized advanced pancreatic cancer after down-stage treatment with a PD-1 inhibitor in combination with chemotherapy. [PDF]

J Cancer Res Clin Oncol
Dang J, Wang Q, Yang Y, Shang L, Kang Z, Jiang Y, Ren Y, Xiang H.   +7 more
europepmc   +1 more source