Results 241 to 250 of about 89,882 (308)

Role of Tryptophan Metabolism in Cancer

Cancer Innovation, Volume 4, Issue 6, December 2025.
This review systematically summarizes the functions and related mechanisms of tryptophan metabolism in various tumor types. It presents the latest progress in this field in a comprehensive manner and combines this with clinical practice to offer a new perspective on tumor treatment.
Zhehao Cui, Dandan Wang, Ye Zhang, Long Yuan, Yi Zhang, Xiaowei Qi   +5 more
wiley   +1 more source

Confirmatory Clinical Validation of a Serum-Based Biomarker Signature for Detection of Early-Stage Pancreatic Ductal Adenocarcinoma. [PDF]

Curr Oncol
Polanco PM, Gonda T, Borazanci E, Glazer ES, Trevino JG, DeMuth G, Ford L, King T, Palma NA, Brand RE.   +9 more
europepmc   +1 more source

mRNA Cancer Vaccines: From Pandemic Paradigm to Personalized Oncology Therapeutics

Cancer Innovation, Volume 4, Issue 6, December 2025.
This review highlights the transformative potential of mRNA cancer vaccines, leveraging technological advancements in nucleotide modification, lipid nanoparticle delivery, and AI‐driven neoantigen selection to enhance vaccine stability, immunogenicity, and personalization.
Bo Yang, Juan Liu, Yang Li, Xiaoxuan Liu
wiley   +1 more source

IL1RA⁺ Myeloid-derived Suppressor Cells Activate Epithelial-mesenchymal Transition to Facilitate Lymphatic and Hepatic Metastasis in Pancreatic Ductal Carcinoma. [PDF]

J Clin Transl Hepatol
Liu H, Zhang J, Lv S, Peng X, Liu H, Li H, Wei F.   +6 more
europepmc   +1 more source

From Gene to Enzyme: Multidimensional Decoding of the GGT Molecular Family and Its Clinical Tumor Diagnosis

Cancer Medicine, Volume 14, Issue 23, December 2025.
ABSTRACT Background Gamma‐glutamyltransferase (GGT) is a membrane‐bound enzyme involved in glutathione metabolism and oxidative stress regulation. Although it is traditionally viewed as a liver function marker, emerging evidence suggests that its aberrant expression is closely associated with tumorigenesis, progression, and therapeutic resistance ...
Fei Wang, Jianshan Yang, Feng Zhu, Xuebing Xu, Junpeng Zhao, Xudong Xie, Xuyang He, Yuxuan Huang, Lirong Zhou, Xiaogang Hu, Xiaomin Lu, Mingbing Xiao   +11 more
wiley   +1 more source

Postmortem diagnosis of exocrine pancreatic adenocarcinoma mimicking encapsulating peritoneal sclerosis in a cat: Clinical and histopathological insights. [PDF]

Open Vet J
Kobayashi K, Kawabata Y, Kadekaru S, Sakai O, Yoshitake R, Mochizuki Y, Nakamura SI, Kutara K.   +7 more
europepmc   +1 more source

Intraoperative differentiation of pancreatic neoplastic lesions using optical coherence tomography (OCT). [PDF]

Langenbecks Arch Surg
Kist M, Strenge P, Keck T, Weber A, Bronsert P, Abdalla TSA, Wellner UF, Thomaschewski M.   +7 more
europepmc   +1 more source

A Case of Successful Conversion Surgery for <i>BRCA</i>-Mutated Pancreatic Body-Tail Cancer with Multiple Liver Metastases Subsequent to Positive Response to Olaparib Maintenance Therapy after Modified FOLFIRINOX. [PDF]

Surg Case Rep
Yagi K, Hirano K, Kimura N, Tohmatsu Y, Watanabe T, Shibuya K, Yoshioka I, Okuno N, Hirabayashi K, Fujii T.   +9 more
europepmc   +1 more source

Microbiota and Pancreatic Cancer: New Therapeutic Frontiers Between Engineered Microbes, Metabolites and Non-Bacterial Components. [PDF]

Cancers (Basel)
De Lucia SS, Nista EC, Candelli M, Archilei S, Deutschbein F, Capuano E, Gasbarrini A, Franceschi F, Pignataro G.   +8 more
europepmc   +1 more source

How to distinguish pancreatic tumors and assess the necessity for biopsy. [PDF]

World J Gastrointest Endosc
Chien MS, Lin CC, Lai JH.
europepmc   +1 more source