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Renal cell carcinoma (RCC) denotes cancer originated from the renal epithelium and accounts for >90% of cancers in the kidney. The disease encompasses >10 histological and molecular subtypes, of which clear cell RCC (ccRCC) is most common and accounts for most cancer-related deaths. Although somatic VHL mutations have been described for some time, more-
Hsieh, James J.+8 more
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Renal Cell Carcinoma (RCC) has the highest mortality rate of the genitourinary cancers and the incidence of RCC has risen steadily. If detected early, RCC is curable by surgery although a minority are at risk of recurrence. Increasing incidental detection and an ageing population has led to active surveillance as an option for patients with small renal
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Renal cell carcinoma remains a major challenge for urologic oncologists. Over the past year, progress has been made in understanding the molecular biology of this disease and in describing new prognostic factors for outcome following nephrectomy. Studies have better defined patients who might benefit from elective nephron-sparing procedures without ...
David M. Nanus+7 more
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The treatment of renal cell carcinoma (RCC) has changed greatly over the past 15 years. Progress in the surgical management of the primary tumor and increased understanding of the molecular biology and genomics of the disease have led to the development of new therapeutic agents.
W. Kimryn Rathmell+2 more
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Renal cell cancer (RCC) accounts for approximately 2–3 % of all human malignancies and shows a worldwide increase of incidence rate of 2 % per year [1]. It primarily affects men and women at the age of 50–70 years with a twofold higher incidence rate in men.
Börje Ljungberg+2 more
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The Labyrinth of Renal Cell Carcinoma [PDF]
Renal cell carcinoma (RCC) ranks in the top-ten list of malignancies both in males and females [...]
Claudia Manini, José I. López
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The clinical presentation of renal cell carcinoma is often diverse and outcome is notoriously difficult to predict. The only therapy for renal cell carcinoma with curative potential is radical surgery for patients presenting with locoregional disease.
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Renal cell carcinoma in childhood [PDF]
The renal cell carcinoma (RCC) rarely occurs in childhood. We report here 3 cases of RCC in children. Two girls and 1 boy aged 14, 8 and 13 years old, respectively, presented with gross hematuria as their main complaint. They underwent ultrasonography and computerized tomography, which revealed unilateral renal tumor with lymph nodal involvement in all
Barros, Luciano R.+2 more
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Simultaneous Chromophobe renal cell carcinoma and squamous renal cell carcinoma [PDF]
Chromophobe renal cell carcinoma (CHRC) is a neoplasm of the kidney with clinicopathologic peculiarities that seems to be of better prognosis than conventional renal cell carcinoma. Classical and eosinophilic types are the two histological variants recorded.
Carlos González+4 more
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