Results 51 to 60 of about 28,716 (215)

Localization of Na pumps in the tracheal epithelium of the dog. [PDF]

, 1979
Binding of [3H]ouabain by the dog's tracheal epithelium shows a nonspecific component depending linearly on ouabain concentration, and a specific saturable component with a Km of 10(-7) M.
Basbaum, CB, Widdicombe, JH, Yee, JY
core  

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Antiviral Effects of Oleandrin

Journal of Experimental Pharmacology, 2020
Robert A Newman, 1, 2 K Jagannadha Sastry, 3 Ravit Arav-Boger, 4 Hongyi Cai, 5 Rick Matos, 6 Robert Harrod 7 1Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77054, USA; 2Phoenix Biotechnology,
Newman RA, Sastry KJ, Arav-Boger R, Cai H, Matos R, Harrod R   +5 more
doaj  

Novel GSK-3β Inhibitor Neopetroside A Protects Against Murine Myocardial Ischemia/Reperfusion Injury

JACC: Basic to Translational Science, 2022
Summary: Recent trends suggest novel natural compounds as promising treatments for cardiovascular disease. The authors examined how neopetroside A, a natural pyridine nucleoside containing an α-glycoside bond, regulates mitochondrial metabolism and heart
Hyoung Kyu Kim, PhD, Min Kim, PhD, Jubert C. Marquez, PhD, Seung Hun Jeong, PhD, Tae Hee Ko, PhD, Yeon Hee Noh, MS, Pham Trong Kha, PhD, Ha Min Choi, BS, Dong Hyun Kim, PhD, Jong Tae Kim, PhD, Young Il Yang, PhD, Kyung Soo Ko, PhD, Byoung Doo Rhee, PhD, Larisa K. Shubina, PhD, Tatyana N. Makarieva, PhD, Dmitry Y. Yashunsky, PhD, Alexey G. Gerbst, PhD, Nikolay E. Nifantiev, PhD, Valentin A. Stonik, PhD, Jin Han, PhD   +19 more
doaj   +1 more source

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia. [PDF]

, 2013
A long-standing controversy is whether autophagy is a bona fide cause of mammalian cell death. We used a cell-penetrating autophagy-inducing peptide, Tat-Beclin 1, derived from the autophagy protein Beclin 1, to investigate whether high levels of ...
Clarke, P.G., Ginet, V., Green, D.R., Levine, B., Liu, Y., Posner, B., Puyal, J., Shaw, S.Y., Shoji-Kawata, S., Sumpter, R.M., Tran, K.A., Wei, Y., Xavier, R.J., Zhang, L.   +13 more
core   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source

Effect οf elicitοrs οn cell suspensiοn culture οf Urginea maritima L. tοwards prοductiοn οf prοscillaridin A

Frontiers in Bioscience-Landmark, 2022
Background: Urginea maritima (L.f.) Baker (Hyacinthaceae) is a perennial bulbous medicinal plant that is currently at risk of extinction. Squill (white sea onion) is an analogous cardiotonic to digitalis. The purpose of the current work was to assess the
Heba Shahin, Atef A. El-Hela, Mahmοud I. Nasr, Ghada M. Nasr   +3 more
doaj   +1 more source

A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells [PDF]

, 2013
Recent evidence suggests that cardiac glycosides might be used for the treatment of cancer. The ornamental shrub Nerium oleander has been used in traditional medicine for treating several disorders including cancer, and extracts from the leaves of this ...
Burgos Morón, Estefanía, Calderón Montaño, José Manuel, López Lázaro, Miguel, Mateos Cordero, Santiago, Orta Vázquez, Manuel Luis   +4 more
core   +2 more sources

Are Tetrapleura tetraptera Phytochemicals Druggable Against SARS‐CoV‐2 Papain‐Like Protein? A Computational Approach

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
SARS‐CoV2 Omicron and its substrains are still a critical global health issue and extremely contagious, even with widespread vaccination efforts. Hospitalizations and mortality rates linked to these variants are still prevalent. Current therapeutic options face challenges, including low effectiveness, suboptimal pharmacokinetics, and drug resistance ...
Frank Eric Tatsing Foka, Hazel Tumelo Mufhandu   +1 more
wiley   +1 more source

Pharmacist intervention in primary care to improve outcomes in patients with left ventricular systolic dysfunction [PDF]

, 2011
<b>Background</b> Meta-analysis of small trials suggests that pharmacist-led collaborative review and revision of medical treatment may improve outcomes in heart failure.<p></p> <b>Methods and results</b> We studied
Forsyth, P., Greenlaw, N., Jhund, P.S., Lowrie, R., Mair, F.S., McConnachie, A., McMurray, J.J.V., Rae, B.   +7 more
core   +1 more source