Results 251 to 260 of about 1,441,839 (397)

Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience

Experimental Physiology, EarlyView.
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David C. Hutchings, Christopher P. Denton, Luigi Venetucci, Andrew W. Trafford   +3 more
wiley   +1 more source

Ca²⁺ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells. [PDF]

Inflamm Regen
Koide T, Giles WR, Kondo R, Imaizumi Y, Yamamura H, Suzuki Y.   +5 more
europepmc   +1 more source

Palmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes. [PDF]

Proc Natl Acad Sci U S A, 2023
Kuo CS, Dobi S, Gök C, Da Silva Costa A, Main A, Robertson-Gray O, Baptista-Hon D, Wypijewski KJ, Costello H, Hales TG, MacQuaide N, Smith GL, Fuller W.   +12 more
europepmc   +1 more source

Caveolae Differentially Control Phosphorylation of Sarcoplasmic Reticular Proteins Following β2 Adrenoceptor Stimulation in the Adult Cardiac Myocyte [PDF]

, 2010
D. MacDougall, John Colyer, Sarah Calaghan   +2 more
openalex   +1 more source

Cardiac Palmitome Sheds New Light on the Structural and Functional Roles of S-Palmitoylation in Cardiac Myocytes [PDF]

, 2020
Madeleine Miles, Nicholas E. Rodriguez, Min Jiang, Jane E. Tomaszewski, Isabelle Deschênes, Gea‐Ny Tseng   +5 more
openalex   +1 more source

Measurement and control of mechanics of cardiac trabeculae secured by light‐curable hydrogel

Experimental Physiology, EarlyView.
Abstract Isolated cardiac trabeculae are small heart muscle tissue preparations, which have been widely used in in vitro studies of mechanics and energetics function of cardiac muscle. Current instruments for such experimentation often (1) involve delicate mounting of the muscle, (2) constrain investigations to one muscle at a time, and thus (3) limit ...
Emily J. Clark Murphy, Toan Pham, June‐Chiew Han, Kenneth Tran, Khoon S. Lim, Poul M. F. Nielsen, Andrew J. Taberner   +6 more
wiley   +1 more source

Distinct intracellular spatiotemporal expression of Calmodulin genes underlies functional diversity of Calmodulin-dependent signalling in cardiac myocytes. [PDF]

Cardiovasc Res
Bogdanov V, Mariangelo JIE, Soltisz AM, Sakuta G, Pokrass A, Beard C, Orengo BH, Kalinin R, Ulker A, Yunker B, Tikunova S, Thuma J, Xu X, Hund TJ, Veeraraghavan R, Davis JP, Györke S.   +16 more
europepmc   +1 more source

Histone Deacetylase 6 Inhibitor JS28 Prevents Pathological Gene Expression in Cardiac Myocytes. [PDF]

J Am Heart Assoc, 2022
Ngo V, Fleischmann BK, Jung M, Hein L, Lother A.   +4 more
europepmc   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

Experimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson, Man Si, Krystle Trosclair, Ellen Aughenbaugh, Maxine Parkinson, Nicole M. Gautier‐Hall, Megan Watts, Frederica Kizek, Md. Shenuarin Bhuiyan, Paari Dominic, Kathryn A. Hamilton, Edward Glasscock   +11 more
wiley   +1 more source

Evidence that human cardiac myocytes divide after myocardial infarction.

New England Journal of Medicine, 2001
A. Beltrami, K. Urbanek, J. Kajstura, Shaomin Yan, N. Finato, R. Bussani, B. Nadal-Ginard, F. Silvestri, A. Leri, C. Beltrami, P. Anversa   +10 more
semanticscholar   +2 more sources