Results 141 to 150 of about 4,049 (222)
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang +11 more
wiley +1 more source
Molecular and Enzymatic Properties of Cardiac Myosin A as Compared with Those of Skeletal Myosin A
J, BRAHMS, C M, KAY
openaire +2 more sources
Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik +10 more
wiley +1 more source
Human fetal circulating factors from pregnancies complicated by obesity upregulate genes associated with pathological hypertrophy in neonatal rat cardiomyocytes. [PDF]
Vaughan OR +4 more
europepmc +1 more source
Acute Myocarditis: From Pathophysiology to Risk‐Stratified Management—A Clinical Review
Stepwise approach to patients with suspected acute myocarditis, integrating the 2024 American College of Cardiology (ACC) four‐stage classification (Stages A–D) and the 2025 European Society of Cardiology (ESC) inflammatory myopericardial syndrome (IMPS) framework. Step 1 (Initial Assessment): clinical presentation, first‐line investigations (ECG, high‐
Michele Golino +9 more
wiley +1 more source
Transcriptomic Remodeling of Pulmonary Vein Sleeves Suggests a Role in Atrial Arrhythmogenesis in Thoroughbred Horses. [PDF]
Arevalo-Turrubiarte M +8 more
europepmc +1 more source
ABSTRACT To investigate the involvement of metalloproteinases (MMPs) in the context of endurance training and their interactions with renin‐angiotensin signalling (RAS) in stress‐induced pathophysiological responses. Trained rats were submitted to 8‐weeks of endurance treadmill training with chronic mild stress (CMS), TS rats, and without CMS (T).
Vinicius Guzzoni +14 more
wiley +1 more source
Non-muscle tropomyosins inhibit myosin-19 and dynamically localize to mitochondrially associated actin filaments. [PDF]
Thompson CP +4 more
europepmc +1 more source
Abstract Aquaculture has increasingly turned toward plant extracts' usage as functional additives, owing to their rich content of bioactive compounds that enhance growth performance, boost immune responses, and improve antioxidant capacity in cultured species.
Nader N. Hassona +9 more
wiley +1 more source
Danicamtiv increases cardiac mechanical efficiency. [PDF]
Meehan T +4 more
europepmc +1 more source

