Results 31 to 40 of about 648 (69)

Generation of a large-scale vascular bed for the in vitro creation of three-dimensional cardiac tissue

Regenerative Therapy, 2019
Introduction: The definitive treatment for severe heart failure is transplantation. However, only a small number of heart transplants are performed each year due to donor shortages.
Akitoshi Inui, Hidekazu Sekine, Kazunori Sano, Izumi Dobashi, Azumi Yoshida, Katsuhisa Matsuura, Eiji Kobayashi, Minoru Ono, Tatsuya Shimizu   +8 more
doaj   +1 more source

Electroactive Polymeric Composites to Mimic the Electromechanical Properties of Myocardium in Cardiac Tissue Repair

Gels, 2021
Due to the limited regenerative capabilities of cardiomyocytes, incidents of myocardial infarction can cause permanent damage to native myocardium through the formation of acellular, non-conductive scar tissue during wound repair.
Kaylee Meyers, Bruce P. Lee, Rupak M. Rajachar   +2 more
doaj   +1 more source

Advances and Prospects in Using Induced Pluripotent Stem Cells for 3D Bioprinting in Cardiac Tissue Engineering

Reviews in Cardiovascular Medicine
Background: Cardiovascular diseases remain one of the leading causes of death worldwide. Given the limited self-repair capacity of cardiac tissue, cardiac tissue engineering (CTE) aims to develop strategies and materials for repairing ...
Baoluo Du, Ziqiang Dai, Huan Wang, Zhipeng Ren, Dianyuan Li   +4 more
doaj   +1 more source

Cardiac Tissue Engineering: A Journey from Scaffold Fabrication to In Vitro Characterization

Small Science
Cardiac tissue engineering has been rapidly evolving with diverse applications, ranging from the repair of fibrotic tissue caused by “adverse remodeling,” to the replacement of specific segments of heart tissue, and ultimately to the creation of a whole ...
Farinaz Ketabat, Jane Alcorn, Michael E. Kelly, Ildiko Badea, Xiongbiao Chen   +4 more
doaj   +1 more source

Integrative approaches in cardiac tissue engineering: Bridging cellular complexity to create accurate physiological models

iScience
Summary: Recent innovations in cardiac tissue engineering (TE) have yet to fully harness integrative genomic mapping of cellular niches to replicate the spatially organized cellular communities and extracellular matrix (ECM) microniches of the heart ...
Dilip Thomas, Joseph C. Wu
doaj   +1 more source

Advancements in tissue engineering for cardiovascular health: a biomedical engineering perspective

Frontiers in Bioengineering and Biotechnology
Myocardial infarction (MI) stands as a prominent contributor to global cardiovascular disease (CVD) mortality rates. Acute MI (AMI) can result in the loss of a large number of cardiomyocytes (CMs), which the adult heart struggles to replenish due to its ...
Zahra-Sadat Razavi, Madjid Soltani, Madjid Soltani, Madjid Soltani, Golnaz Mahmoudvand, Simin Farokhi, Arian Karimi-Rouzbahani, Bahareh Farasati-Far, Samaneh Tahmasebi-Ghorabi, Hamidreza Pazoki-Toroudi, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami   +12 more
doaj   +1 more source

Chitosan–Polyethylene Glycol Inspired Polyelectrolyte Complex Hydrogel Templates Favoring NEO-Tissue Formation for Cardiac Tissue Engineering

Gels
Neo-tissue formation and host tissue regeneration determine the success of cardiac tissue engineering where functional hydrogel scaffolds act as cardiac (extracellular matrix) ECM mimic.
Angelo Keklikian, Natan Roberto de Barros, Ahmad Rashad, Yiqing Chen, Jinrui Tan, Ruoyu Sheng, Dongwei Sun, Huinan Liu, Finosh G. Thankam   +8 more
doaj   +1 more source

Cardiac tissue engineering: current state-of-the-art materials, cells and tissue formation

Einstein (São Paulo)
Cardiovascular diseases are the major cause of death worldwide. The heart has limited capacity of regeneration, therefore, transplantation is the only solution in some cases despite presenting many disadvantages.
Isabella Caroline Pereira Rodrigues, Andreas Kaasi, Rubens Maciel Filho, André Luiz Jardini, Laís Pellizzer Gabriel   +4 more
doaj   +1 more source

Channeled ECM-Based Nanofibrous Hydrogel for Engineering Vascularized Cardiac Tissues

Nanomaterials, 2019
Hydrogels are widely used materials for cardiac tissue engineering. However, once the cells are encapsulated within hydrogels, mass transfer to the core of the engineered tissue is limited, and cell viability is compromised.
Smadar Arvatz, Lior Wertheim, Sharon Fleischer, Assaf Shapira, Tal Dvir   +4 more
doaj   +1 more source

Tissue Engineering to Restore Cardiac Function

Engineering, 2022
Richard D. Weisel
doaj   +1 more source