Results 11 to 20 of about 36,754 (231)
Ionization constants pKa of cardiolipin. [PDF]
PLoS ONE, 2013 Cardiolipin is a phospholipid found in the inner mitochondrial membrane and in bacteria, and it is associated with many physiological functions. Cardiolipin has a dimeric structure consisting of two phosphatidyl residues connected by a glycerol bridge ...
Gerd Olofsson, Emma Sparr
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StaR-related lipid transfer-like domain-containing protein CLDP43 affects cardiolipin synthesis and mitochondrial function in Trypanosoma brucei. [PDF]
PLoS ONE, 2022 Cardiolipin is known to interact with bacterial and mitochondrial proteins and protein complexes. Unlike in Escherichia coli and Saccharomyces cerevisiae, the synthesis of cardiolipin is essential for growth of Trypanosoma brucei parasites in culture ...
Alessio Loffreda +2 more
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Assessing phospholipase A2 activity toward cardiolipin by mass spectrometry. [PDF]
PLoS ONE, 2013 Cardiolipin, a major component of mitochondria, is critical for mitochondrial functioning including the regulation of cytochrome c release during apoptosis and proper electron transport.
Yuan-Hao Hsu +3 more
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Cross-species complementation of bacterial- and eukaryotic-type cardiolipin synthases [PDF]
Microbial Cell, 2017 The glycerophospholipid cardiolipin is a unique constituent of bacterial and mitochondrial membranes. It is involved in forming and stabilizing high molecular mass membrane protein complexes and in maintaining membrane architecture.
Petra Gottier +4 more
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Cardiolipin Alterations during Obesity: Exploring Therapeutic Opportunities
Biology, 2022 Cardiolipin is a specific phospholipid of the mitochondrial inner membrane that participates in many aspects of its organization and function, hence promoting proper mitochondrial ATP production.
Alexandre Prola, Fanny Pilot-Storck
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Nature Communications, 2023 Cardiolipin is a hallmark phospholipid of mitochondrial membranes. Despite established significance of cardiolipin in supporting respiratory supercomplex organization, a mechanistic understanding of this lipid-protein interaction is still lacking.
Corey F. Hryc +9 more
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Cardiolipin and the Nlrp3 Inflammasome [PDF]
Cell Metabolism, 2013 The Nlrp3 inflammasome is a key controller of the proinflammatory cytokine IL-1β. Iyer and colleagues (2013) demonstrate that Nlrp3 activators promote an interaction between cardiolipin in mitochondria and Nlrp3. Cardiolipin is thus a hydrophobic danger signal that, upon translocation to the outer mitochondrial membrane, activates Nlrp3, promoting ...
O’Neill, Luke A.J., O\u27NEILL, LUKE
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Cardiolipin’s multifaceted role in immune response: a focus on interacting proteins [PDF]
Frontiers in ImmunologyCardiolipin is a unique and essential phospholipid that plays a pivotal role in cellular function. In eukaryotic cells, it is predominantly localized within the mitochondrial membranes, with the highest concentration in the inner mitochondrial membrane ...
Zhuodong Chai +9 more
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The cardiolipin analogues of Archaea
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009 The present article reviews studies of the structure and functional roles of the cardiolipin analogues of extremely halophilic prokaryotes belonging to the Archaea domain. Analogies and differences between the archaeal bisphosphatidylglycerol and the mitochondrial cardiolipin are presented. Furthermore the structure of archaeal glycophospholipid dimers
CORCELLI, Angela
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Mieap forms membrane-less organelles involved in cardiolipin metabolism
iScienceSummary: Biomolecular condensates (BCs) are formed by proteins with intrinsically disordered regions (IDRs) via liquid-liquid phase separation. Mieap/Spata18, a p53-inducible protein, participates in suppression of colorectal tumors by promoting ...
Naoki Ikari +4 more
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