Results 31 to 40 of about 36,754 (231)
Cardiolipin Interactions with Proteins [PDF]
Biophysical Journal, 2015 Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria with four acyl chains and two phosphate groups that have been implicated in numerous functions from energy metabolism to apoptosis. Many proteins are known to interact with CL, and several cocrystal structures of protein-CL complexes exist.
Planas-Iglesias, Joan +5 more
openaire +2 more sources
Structure of Cardiolipin [PDF]
Nature, 1958 PANGBORN1 considered that the glycerylglycero-phosphate skeleton of cardiolipin contained three phosphoric acid and four glycerol residues (I), the six available hydroxyl groups in this structure being esterified with unsaturated fatty acids in the intact phospholipid.
openaire +2 more sources
Membranes, 2023 Cardiolipin is one of the main phospholipid components of Staphylococcus aureus membranes. This lipid is found at varying concentrations in the bilayer, depending on the growth stage of the bacteria, and as a response to environmental stress. Cardiolipin
Nathalia Calderón-Rivera +5 more
doaj +1 more source
Measuring cardiolipin antibodies [PDF]
BMJ, 1995 EDITOR,—Cardiolipin antibodies have been variously cited as a risk factor for cerebral thrombosis1 2 or splanchnic venous thrombosis,3 or as an epiphenomenon loosely associated with vascular disease.4 Cardiolipin antibodies seem to represent a family of low affinity antibodies which share a limited ability to bind to bovine cardiolipin.
A M, Ward, P A, White
openaire +2 more sources
Journal of Lipid Research, 2010 An improved high-performance liquid chromatography-mass spectrometry method for the separation and characterization of cardiolipin molecular species is presented.
Paul E. Minkler, Charles L. Hoppel
doaj +1 more source
Clarifying the Roles of Cardiolipin [PDF]
Biophysical Journal, 2014 Cardiolipins (CL) are uniquely structured double lipids that are universally found in membranes which couple electron transport and phosphorylation. The proposed roles of CL in these membranes include mainly two aspects: the effects on the structure and dynamics of the membranes' lipid component and the interplay with membrane-associated proteins.
Pöyry, Sanja +7 more
openaire +1 more source
An essential bacterial-type cardiolipin synthase mediates cardiolipin formation in a eukaryote
, 2012 Cardiolipin is important for bacterial and mitochondrial stability and function. The final step in cardiolipin biosynthesis is catalyzed by cardiolipin synthase and differs mechanistically between prokaryotes and eukaryotes.
Bütikofer, Peter, Serricchio, Mauro
core +1 more source
, 2018 The mitochondrial glycerophospholipid cardiolipin plays important roles in mitochondrial biology. Most notably, cardiolipin directly binds to mitochondrial proteins and helps assemble and stabilize mitochondrial multi-protein complexes.
Vissa, Adriano +9 more
core +1 more source
Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein
Nature Communications, 2018 Cardiolipin is a phospholipid component of the inner mitochondrial membrane. Here the authors demonstrate that cardiolipin interacts with mutant α-synuclein, and that impaired cardiolipin function can lead to spread of α-synuclein between neurons.
Tammy Ryan +10 more
doaj +1 more source
Cardiolipin Synthesis and Outer Membrane Localization Are Required for
mBio, 2017 Cardiolipin, an anionic phospholipid that resides at the poles of the inner and outer membranes, is synthesized primarily by the putative cardiolipin synthase ClsA in Shigella flexneri. An S.
Rachael M. Rossi +3 more
doaj +1 more source