Results 101 to 110 of about 8,226 (286)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Unusual butane- and pentanetriol-based tetraether lipids in Methanomassiliicoccus luminyensis, a representative of the seventh order of methanogens [PDF]

, 2016
Author Posting. © The Author(s), 2016. This is the author's version of the work. It is posted here by permission of American Society for Microbiology for personal use, not for redistribution.
Becker, Kevin W., Elling, Felix J., Hinrichs, Kai-Uwe, Sollinger, Andrea, Urich, Tim, Yoshinaga, Marcos Y.   +5 more
core   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

Small, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi, Benedikt Kronast, Jennifer Munkert, Lorenzo Sana, Marcus Koch, Heike Danzer, Sirka Dormeyer, Shuhan Jiang, Fabian Herrmann, Matthias Weiler, Anna Kashkanova, Vahid Sandoghdar, Mario M. Zaiss, Gregor Fuhrmann   +13 more
wiley   +1 more source

Insulin-induced lipid body accumulation is accompanied by lipid remodelling in model mast cells

Adipocyte, 2019
Mast cell lipid bodies are key to initiation, maintenance and resolution of inflammatory responses in tissue. Mast cell lines, primary bone marrow-derived mast cells and peripheral blood basophils present a ‘steatotic’ phenotype in response to chronic ...
Johnny T. Aldan, Chad Jansen, Mark Speck, Kristina Maaetoft-Udsen, Edward A. Cordasco, Mata’Uitafa Faiai, Lori M.N. Shimoda, William E. Greineisen, Helen Turner, Alexander J. Stokes   +9 more
doaj   +1 more source

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, EarlyView.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

Sci Signal [PDF]

Among the distinct molecular signatures present in the mitochondrion is the tetra-acylated anionic phospholipid cardiolipin, a lipid also present in primordial, single-cell bacterial ancestors of mitochondria and multiple bacterial species today ...

core  

Genotypic and Lipid Analyses of Strains From the Archaeal Genus Halorubrum Reveal Insights Into Their Taxonomy, Divergence, and Population Structure [PDF]

, 2018
To gain a better understanding of how divergence occurs, and how taxonomy can benefit from studying natural populations, we isolated and examined 25 closely related Halorubrum strains obtained from different hypersaline communities and compared them to ...
Corral Villa, Paulina, Infante Domínguez, María del Carmen, Ruiz de la Haba, Rafael, Sánchez-Porro Álvarez, Cristina, Ventosa Ucero, Antonio   +4 more
core   +1 more source

Carvacrol alters the membrane phospholipids in erythromycin-resistant Streptococcus pyogenes

Phytomedicine Plus
Background: Phospholipids are significant constituents of bacterial membranes. Bacteria can alter their cytoplasmic membrane fatty acid composition in response to changing environmental stress conditions. Carvacrol, a mono-terpenoid phenol, has excellent
Niluni M. Wijesundara, Song F. Lee, David N. Langelaan, Abir Lefsay, H.P. Vasantha Rupasinghe   +4 more
doaj   +1 more source

Sensing of cardiolipin exposure on plasma membranes of apoptotic cells by EryA‐mCherry protein

The FEBS Journal, EarlyView.
An aegerolysin protein erylysin A (EryA) fused with mCherry binds to artificial lipid vesicles supplemented with cardiolipin (CL). This binding is much more specific than that of annexin V, which binds various negatively charged glycerophospholipids (PG, PS, PI). In mammalian cells, the CL exposition at the membrane surface represents an early hallmark
Luka Žeželj, Tadeja Bele, Anastasija Panevska, Gregor Bajc, Jan Kejžar, Miha Bahun, Nataša Poklar Ulrih, Valentina Levak, Matej Skočaj, Larisa Lara Popošek, Peter Veranič, Nataša Resnik, Kristina Sepčić   +12 more
wiley   +1 more source

Multilayered lipid membrane stacks for biocatalysis using membrane enzymes [PDF]

, 2017
Multilayered or stacked lipid membranes are a common principle in biology and have various functional advantages compared to single lipid membranes, such as their ability to spatially organize processes, compartmentalize molecules and greatly increase ...
Butt, JN, Frielingsdorf, S, Heath, GR, Jeuken, LJC, Lenz, O, Li, M, Radu, V, Rong, H   +7 more
core   +2 more sources