Results 1 to 10 of about 20,955 (188)
Cardioprotection and ageing [PDF]
Korean Journal of Anesthesiology, 2010 With an increase in the elderly population and an increase in the prevalence of age-related cardiovascular disease, anesthesiologists are increasingly being faced with elderly patients with known or suspected ischemic heart disease in the perioperative ...
Yon Hee Shim
doaj +4 more sources
Telmisartan and cardioprotection
Vascular Health and Risk Management, 2011 Philippe R Akhrass, Samy I McFarlaneState University of New York, Downstate Medical Center, Brooklyn, NY, USAAbstract: Cardiovascular risk reduction has been the target of several large clinical trials in the last decade.
McFarlane S
doaj +4 more sources
BMC Research Notes, 2021 Objectives In pulmonary arterial hypertension (PAH), right ventricular (RV) dysfunction develops via mechanisms involving oxidative stress. Moderate and chronic red wine (RW) consumption reduces oxidative stress and confers cardioprotection but its ...
Patrick Diaba-Nuhoho +5 more
doaj +1 more source
Perioperative cardioprotection [PDF]
F1000Prime Reports, 2013 Although anaesthesia itself is now very safe, perioperative cardiac complications during non-cardiovascular surgery are a major cause of morbidity and mortality, because of the increasingly high underlying prevalence of cardiovascular disease. Fortunately, although there is no "magic bullet", pharmacological intervention can reduce the risk.
Leung, KMM, Irwin, MG
openaire +4 more sources
Anthracycline-induced cardiotoxicity: targeting high-density lipoproteins to limit the damage?
Lipids in Health and Disease, 2022 Doxorubicin (DOX) is an anthracycline antibiotic frequently used against a wide range of cancers, including breast cancer. Although the drug is effective as a treatment against cancer, many patients develop heart failure (HF) months to years following ...
Carmelita Abrahams +2 more
doaj +1 more source
Ubiquinol-cytochrome c reductase core protein 1 may be involved in delayed cardioprotection from preconditioning induced by diazoxide. [PDF]
PLoS ONE, 2017 This study aimed to use long-term diazoxide treatment to establish a loss-of-cardioprotection model and then perform proteomics analysis to explore which proteins of mitochondrial inner membrane (MIM) are potentially involved in delayed cardioprotection.
Zonghong Long +7 more
doaj +1 more source
Frontiers in Physiology, 2022 Mitochondria-associated endoplasmic reticulum membranes (MAMs) are important components of intracellular signaling and contribute to the regulation of intracellular Ca2+/lipid homeostasis, mitochondrial dynamics, autophagy/mitophagy, apoptosis, and ...
Yuhu Lv, Lin Cheng, Fenglin Peng
doaj +1 more source
Mitophagy for cardioprotection
Basic Research in Cardiology, 2023 AbstractMitochondrial function is maintained by several strictly coordinated mechanisms, collectively termed mitochondrial quality control mechanisms, including fusion and fission, degradation, and biogenesis. As the primary source of energy in cardiomyocytes, mitochondria are the central organelle for maintaining cardiac function.
Allen Sam Titus +3 more
openaire +2 more sources
Circulation, 2008 Over the past 2 to 3 decades, several phenomena have been identified that provide powerful protection against myocardial infarction and other sequelae of ischemia/reperfusion1: myocardial hibernation that is related to stunning,2 ischemic preconditioning,3 delayed or second-window ischemic preconditioning,4 ischemic postconditioning,5 and their ...
Gerd Heusch +2 more
openaire +1 more source
Cells, 2021 Myocardial ischemia–reperfusion (I/R) injury significantly alters heart function following infarct and increases the risk of heart failure. Many studies have sought to preserve irreplaceable myocardium, termed cardioprotection, but few, if any ...
Kevin M. Casin, John W. Calvert
doaj +1 more source