Results 11 to 20 of about 46,462 (246)

Cardioprotection and ageing [PDF]

Korean Journal of Anesthesiology, 2010
With an increase in the elderly population and an increase in the prevalence of age-related cardiovascular disease, anesthesiologists are increasingly being faced with elderly patients with known or suspected ischemic heart disease in the perioperative ...
Yon Hee Shim
doaj   +4 more sources

Telmisartan and cardioprotection

Vascular Health and Risk Management, 2011
Philippe R Akhrass, Samy I McFarlaneState University of New York, Downstate Medical Center, Brooklyn, NY, USAAbstract: Cardiovascular risk reduction has been the target of several large clinical trials in the last decade.
McFarlane S
doaj   +4 more sources

Perioperative cardioprotection [PDF]

F1000Prime Reports, 2013
Although anaesthesia itself is now very safe, perioperative cardiac complications during non-cardiovascular surgery are a major cause of morbidity and mortality, because of the increasingly high underlying prevalence of cardiovascular disease. Fortunately, although there is no "magic bullet", pharmacological intervention can reduce the risk.
Leung, KMM, Irwin, MG
openaire   +4 more sources

Mitophagy for cardioprotection

Basic Research in Cardiology, 2023
AbstractMitochondrial function is maintained by several strictly coordinated mechanisms, collectively termed mitochondrial quality control mechanisms, including fusion and fission, degradation, and biogenesis. As the primary source of energy in cardiomyocytes, mitochondria are the central organelle for maintaining cardiac function.
Allen Sam Titus, Eun-Ah Sung, Daniela Zablocki, Junichi Sadoshima   +3 more
openaire   +2 more sources

Cardioprotection [PDF]

Circulation, 2008
Over the past 2 to 3 decades, several phenomena have been identified that provide powerful protection against myocardial infarction and other sequelae of ischemia/reperfusion1: myocardial hibernation that is related to stunning,2 ischemic preconditioning,3 delayed or second-window ischemic preconditioning,4 ischemic postconditioning,5 and their ...
Gerd Heusch, Kerstin Boengler, Rainer Schulz   +2 more
openaire   +1 more source

The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction [PDF]

, 2017
Ample evidence identifies strong links between major depressive disorder (MDD) and both risk of ischemic or coronary heart disease (CHD) and resultant morbidity and mortality. The molecular mechanistic bases of these linkages are poorly defined. Systemic
Budiono, Boris P, Headrick, John P., Neumann, David L., Peart, Jason N., Shum, David H K, Stapelberg, Nicolas J C   +5 more
core   +1 more source

Estrogen Protects the Female Heart from Ischemia/Reperfusion Injury through Manganese Superoxide Dismutase Phosphorylation by Mitochondrial p38β at Threonine 79 and Serine 106. [PDF]

, 2016
A collective body of evidence indicates that estrogen protects the heart from myocardial ischemia/reperfusion (I/R) injury, but the underlying mechanism remains incompletely understood. We have previously delineated a novel mechanism of how 17β-estradiol
Kim, Jin Kyung, Liu, Han, Luo, Tao
core   +1 more source

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology [PDF]

, 2018
Due to its poor capacity for regeneration, the heart is particularly sensitive to the loss of contractile cardiomyocytes. The onslaught of damage caused by ischaemia and reperfusion, occurring during an acute myocardial infarction and the subsequent ...
A Ames 3rd, A Carvalho, A Gaspar, A Maulik, AA Neuhaus, AC Schinzel, AD Sloth, Arjun K. Ghosh, AS Hazell, B Ibanez, B Ibanez, Borja Ibanez, CC Smith, CE Murry, CP Baines, D Li, Daniel I. Bromage, Derek M. Yellon, DI Bromage, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, ET Chouchani, F Chauveau, F Chen, F Pedersen, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, GA Donnan, GA Donnan, Gerd Heusch, GF Baxter, GP Fadini, GW Stone, H Sandhu, HA Cabrera-Fuentes, Hans Erik Bøtker, HE Botker, Helen Maddock, I Eitel, J Aronowski, J Astrup, J Bai, J Inserte, J Johnsen, JC Wang, JE Jung, JL Saver, JM Vicencio, John Cunningham, JP Audia, JPG Sluijter, JS Balami, JV McGowan, K Szummer, KL Furie, L Zhang, M Fisher, M Gharanei, M Gharanei, M Schmidt, M Thielmann, Malcolm Walker, Marlene Wiart, Maryna V. Basalay, MD Ginsberg, Michel Ovize, MV Cohen, N Nighoghossian, P Kleinbongard, P Meybohm, PA Lapchak, PA Lapchak, Petra Kleinbongard, R Bell, R Bonita, R Chung, R Madonna, RA Kloner, Richard D. Carr, RM Bell, RM Bell, Robert M. Bell, RR Liu, RR Moustafa, S Lecour, S Pundik, SA Crone, Sandrine Lecour, Sapna Arjun, Sean M. Davidson, SI Savitz, SM Davidson, SM Davidson, SM Davidson, SM Davidson, SP Jones, TA Zelniker, VE O’Collins, VE O’Collins, VL Feigin, W Li, X Rossello, X Rossello, X Xu, Y Li, Z Vermeulen   +117 more
core   +6 more sources

Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI). [PDF]

, 2014
AIM: Despite prompt revascularization of acute myocardial infarction (AMI), substantial myocardial injury may occur, in part a consequence of ischaemia reperfusion injury (IRI). There has been considerable interest in therapies that may reduce IRI.
A. de Belder, A. Hannah, A. McDonald, A. Stewart, A. Struthers, B. Jagpal, Bolli, C. Lang, C. Neil, C. Neil, D. Dawson, D. Dawson, D. Garg, D. Hildick-Smith, D. Hildick-Smith, D. Hogg, D. Roy, E. Jansen, E. Roberts, E. Slattery, F. Gonzalvez, Flett, G. MacLennan, G. MacLennan, G. McPherson, Gori, H. Dargie, J. C. Kaski, J. Horowitz, J. Horowitz, J. Rhodes, J.-C. Kaski, K. Schwarz, L. Bennett, Lundberg, Lundberg, M. Black, M. Bruce, M. Bruce, M. Feelisch, M. Frenneaux, M. Frenneaux, M. Madhani, M. Metcalfe, Murillo, Murry, N. Awsan, N. Boon, N. Boon, N. Bunce, N. Cooter, N. Siddiqi, N. Siddiqi, P. Broadhurst, P. Nightingale, P. O. Lim, P. O. Lim, Piot, R. Bogle, R. Dautov, S. A. Papadopoulou, S. Brown, S. Cotton, S. Cotton, S. Firoozi, S. Papadopoulou, S. Rajendran, S. Singh, Shiva, Srihirun, T. Davidson, Tsang, W. Toff, White   +73 more
core   +3 more sources

Opioid-induced Cardioprotection [PDF]

Current Pharmaceutical Design, 2014
Ischemic heart disease and myocardial infarction continue to be leading causes of cardiovascular morbidity and mortality. Activation of opioid, adenosine, bradykinin, adrenergic and other G-protein coupled receptors has been found to be cardioprotective.
Katsuya, Tanaka, Judy R, Kersten, Matthias L, Riess   +2 more
openaire   +2 more sources