Results 31 to 40 of about 31,146 (236)

Targeting myocardial equilibrative nucleoside transporter ENT1 provides cardioprotection by enhancing myeloid Adora2b signaling

JCI Insight, 2023
Previous studies implicate extracellular adenosine signaling in attenuating myocardial ischemia and reperfusion injury (IRI). This extracellular adenosine signaling is terminated by its uptake into cells by equilibrative nucleoside transporters (ENTs ...
Wei Ruan, Jiwen Li, Seungwon Choi, Xinxin Ma, Yafen Liang, Ragini Nair, Xiaoyi Yuan, Tingting W. Mills, Holger K. Eltzschig   +8 more
doaj   +1 more source

A brief overview of cardioprotective signaling [PDF]

Arhiv za farmaciju
Cardioprotection is defined as the intrinsic ability of cardiac tissue to withstand challenges like ischemia-reperfusion and different metabolic stresses.
Jovanović Aleksandar
doaj   +1 more source

Cardioprotection conferred by rooibos (Aspalathus linearis): A mini review to highlight a potential mechanism of action

South African Journal of Science, 2019
A number of cardioprotective interventions have been identified throughout the years, and these include the use of natural antioxidants in sources like rooibos (Aspalathus linearis) tea.
Gerald J. Maarman
doaj   +1 more source

Cardioprotection for acute MI in light of the CONDI2/ERIC-PPCI trial: New targets needed [PDF]

, 2020
Protection against ischaemia-reperfusion injury after revascularisation in acute myocardial infarction remains an enigma. Many targets have been identified, but after the failure of the recent Effect of Remote Ischaemic Conditioning on Clinical Outcomes ...
Giblett, Joel P., Bulluck, Heerajnarain, Joel P Giblett, Bulluck, H, Heerajnarain Bulluck, Giblett, JP   +5 more
core   +1 more source

Impact of hyperglycemia on myocardial ischemia–reperfusion susceptibility and ischemic preconditioning in hearts from rats with type 2 diabetes

Cardiovascular Diabetology, 2019
Background The mechanisms underlying increased mortality in patients with diabetes and admission hyperglycemia after an acute coronary syndrome may involve reduced capacity for cardioprotection.
Steen Buus Kristiansen, Kim Bolther Pælestik, Jacob Johnsen, Nichlas Riise Jespersen, Kasper Pryds, Marie Vognstoft Hjortbak, Rebekka Vibjerg Jensen, Hans Erik Bøtker   +7 more
doaj   +1 more source

M3 subtype of muscarinic acetylcholine receptor promotes cardioprotection via the suppression of miR-376b-5p. [PDF]

PLoS ONE, 2012
The M(3) subtype of muscarinic acetylcholine receptors (M(3)-mAChR) plays a protective role in myocardial ischemia and microRNAs (miRNAs) participate in many cardiac pathophysiological processes, including ischemia-induced cardiac injury.
Zhenyu Pan, Yueping Guo, Hanping Qi, Kai Fan, Shu Wang, Hua Zhao, Yuhua Fan, Jing Xie, Feng Guo, Yunlong Hou, Ning Wang, Rong Huo, Yong Zhang, Yan Liu, Zhimin Du   +14 more
doaj   +1 more source

Role of Macrophages in Cardioprotection [PDF]

International Journal of Molecular Sciences, 2019
Cardiovascular diseases are the leading cause of mortality worldwide. It is widely known that non-resolving inflammation results in atherosclerotic conditions, which are responsible for a host of downstream pathologies including thrombosis, myocardial infarction (MI), and neurovascular events.
Jonathan Yap, Hector A. Cabrera-Fuentes, Jason Irei, Derek J. Hausenloy, William A. Boisvert   +4 more
openaire   +4 more sources

Role of atrial natriuretic peptide in abrogated cardio protective effect of ischemic postconditioning in diabetic rat heart

Biomedical and Biotechnology Research Journal, 2022
Background: Diabetes decreased cardioprotective potential of ischemic postconditioning (IPOC), atrial natriuretic peptide (ANP) induced the cardioprotection against ischemic-reperfusion (I/R) injury. The present study has been designed to investigate the
Garima Gupta, Vibhav Varshney, Ahsas Goyal, Jeetendra K Gupta, H N Yadav   +4 more
doaj   +1 more source

The role of Toll-like receptor 4 (TLR-4) in wine-induced cardioprotection [PDF]

, 2012
Includes abstract.Includes bibliographical references.Moderate and chronic consumption of red wine confers cardioprotection. Melatonin, present in wine, may contribute to this cardioprotective effect. Melatonin confers cardioprotection via the activation
Albertyn, Zulfah
core   +1 more source

Morphine and remifentanil-induced cardioprotection: its experimental and clinical outcomes [PDF]

Korean Journal of Anesthesiology, 2011
During the past few decades, a large number of animal studies demonstrated that commonly used opioids could provide cardioprotection against ischemia-reperfusion (I/R) injury.
Jin Mo Kim, Young Ho Jang, Jun Kim
doaj   +1 more source