Results 11 to 20 of about 55,383 (254)
Vascular smooth muscle BK channels limit ouabain‐induced vasocontraction: dual role of the Na/K‐ATPase as a hub for Src‐kinase and the Na/Ca‐exchanger [PDF]
Large-conductance, calcium-activated potassium channels (BK channels) and the Na/K-ATPase are expressed universally in vascular smooth muscle. The Na/K-ATPase may act via changes in the intracellular Ca2+ concentration mediated by the Na/Ca exchanger ...
Jepps, Thomas A.+10 more
core +2 more sources
Pharmacological properties of amrinone, a cardiotonic agent
Shinjiroh Murata+4 more
openaire +3 more sources
Acute poisoning by cardiovascular agents [PDF]
In order to determine the frequency, severity of poisoning, and the efficacy of the applied therapeutic measures, retrospective study of 391 patients treated for acute drug poisoning was performed during one-year period at the Clinic for Emergency and ...
Vučinić Slavica+5 more
doaj +1 more source
Improving of Robotic Virtual Agent's errors that are accepted by reaction and human's preference [PDF]
One way to improve the relationship between humans and anthropomorphic agents is to have humans empathize with the agents. In this study, we focused on a task between an agent and a human in which the agent makes a mistake. To investigate significant factors for designing a robotic agent that can promote humans empathy, we experimentally examined the ...
arxiv +1 more source
Steroids—has the time come to extend their use to AML?
Background In 2018, leukaemia accounted for 2.6% of all new cancers, it being the 13th most common cause of cancer and the 10th most common cause of cancer death. Glucocorticoids are commonly used in lymphoid leukaemia treatment, where they are cytotoxic.
Mariah Farrugia+3 more
doaj +1 more source
Cardiac Glycosides as Immune System Modulators
Cardiac glycosides (CGs) are natural steroid compounds occurring both in plants and animals. They are known for long as cardiotonic agents commonly used for various cardiac diseases due to inhibition of Na+/K+-ATPase (NKA) pumping activity and modulating
Jan Škubník+2 more
doaj +1 more source
Antiviral activity of ouabain against a Brazilian Zika virus strain
Zika virus (ZIKV) is an emerging arbovirus associated with neurological disorders. Currently, no specific vaccines or antivirals are available to treat the ZIKV infection.
Deyse Cristina Madruga Carvalho+9 more
doaj +1 more source
Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics
Cardiac glycosides are natural sterols and constitute a group of secondary metabolites isolated from plants and animals. These cardiotonic agents are well recognized and accepted in the treatment of various cardiac diseases as they can increase the rate ...
Ranjith Kumavath+6 more
doaj +1 more source
Clinical Characteristics and Treatment of Atrial Fibrillation and Heart Failure: a Multicenter Survey [PDF]
Background Atrial fibrillation (AF) is a common clinical tachyarrhythmia with high prevalence, and a predisposing factor of stroke. In addition, it has a causal relationship with heart failure (HF) .
HU Huachao, CHEN Xianya, XIE Siyuan, XIA Zhen, XIAO Hua
doaj +1 more source
Socially interactive agents (SIAs) are no longer mere visions for future user interfaces, as 20 years of research and technology development has enabled the use of virtual and physical agents in day-to-day interfaces and environments. This chapter of the ACM "The Handbook on Socially Interactive Agents" reviews research on and technologies involving ...
arxiv +1 more source