Results 11 to 20 of about 3,273,209 (295)
Steroids—has the time come to extend their use to AML?
Journal of the Egyptian National Cancer Institute, 2021 Background In 2018, leukaemia accounted for 2.6% of all new cancers, it being the 13th most common cause of cancer and the 10th most common cause of cancer death. Glucocorticoids are commonly used in lymphoid leukaemia treatment, where they are cytotoxic.
Mariah Farrugia +3 more
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Cardiac Glycosides as Immune System Modulators
Biomolecules, 2021 Cardiac glycosides (CGs) are natural steroid compounds occurring both in plants and animals. They are known for long as cardiotonic agents commonly used for various cardiac diseases due to inhibition of Na+/K+-ATPase (NKA) pumping activity and modulating
Jan Škubník +2 more
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Antiviral activity of ouabain against a Brazilian Zika virus strain
Scientific Reports, 2022 Zika virus (ZIKV) is an emerging arbovirus associated with neurological disorders. Currently, no specific vaccines or antivirals are available to treat the ZIKV infection.
Deyse Cristina Madruga Carvalho +9 more
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Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics
Biomolecules, 2021 Cardiac glycosides are natural sterols and constitute a group of secondary metabolites isolated from plants and animals. These cardiotonic agents are well recognized and accepted in the treatment of various cardiac diseases as they can increase the rate ...
Ranjith Kumavath +6 more
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Viruses, 2021 Therapeutic options for coronaviruses remain limited. To address this unmet medical need, we screened 5406 compounds, including United States Food and Drug Administration (FDA)-approved drugs and bioactives, for activity against a South Korean Middle ...
Meehyun Ko +12 more
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Clinical Characteristics and Treatment of Atrial Fibrillation and Heart Failure: a Multicenter Survey [PDF]
Zhongguo quanke yixue, 2023 Background Atrial fibrillation (AF) is a common clinical tachyarrhythmia with high prevalence, and a predisposing factor of stroke. In addition, it has a causal relationship with heart failure (HF) .
HU Huachao, CHEN Xianya, XIE Siyuan, XIA Zhen, XIAO Hua
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Frontiers in Pharmacology, 2023 Aberrant mitophagy has been identified as a driver for energy metabolism disorder in most cardiac pathological processes. However, finding effective targeted agents and uncovering their precise modulatory mechanisms remain unconquered.
Ji-Chao Zhou +20 more
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Lipid Emulsion to Treat Acute Poisonings: Mechanisms of Action, Indications, and Controversies
Pharmaceutics, 2023 Biodetoxification using intravenous lipid emulsion (ILE) in acute poisoning is of growing interest. As well as for local anesthetics, ILE is currently used to reverse toxicity caused by a broad-spectrum of lipophilic drugs.
Karim Jaffal +2 more
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