Results 41 to 50 of about 3,273,209 (295)
Why has positive inotropy failed in chronic heart failure? Lessons from prior inotrope trials. [PDF]
Current pharmacological therapies for heart failure with reduced ejection fraction are largely either repurposed anti-hypertensives that blunt overactivation of the neurohormonal system or diuretics that decrease congestion.
Ahmad, T +10 more
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An Evaluation of Traditional Persian Medicine for the Management of SARS-CoV-2
A new coronavirus causing severe acute respiratory syndrome (SARS-CoV-2) has emerged and with it, a global investigation of new antiviral treatments and supportive care for organ failure due to this life-threatening viral infection.
Roodabeh Bahramsoltani +3 more
doaj +1 more source
Evaluating the cancer therapeutic potential of cardiac glycosides [PDF]
Cardiac glycosides, also known as cardiotonic steroids, are a group of natural products that share a steroid-like structure with an unsaturated lactone ring and the ability to induce cardiotonic effects mediated by a selective inhibition of the Na(+)/K(+)
Burgos Morón, Estefanía +5 more
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Correlation between endogenous polyamines in human cardiac tissues and clinical parameters in patients with heart failure [PDF]
This work was supported by a grant from the Instituto de Salud Carlos III(FISS03-1497), from which Clara Meana was recipient of a fellowships. CM, CB and LS designed and performed the biochemical experiments, JB designed and performed the experiments of ...
Bordallo Landa, Javier +5 more
core +2 more sources
Ion pumps as biological targets for decavanadate [PDF]
The putative applications of poly-, oligo- and mono-oxometalates in biochemistry, biology, pharmacology and medicine are rapidly attracting interest. In particular, these compounds may act as potent ion pump inhibitors and have the potential to play a ...
Aureliano, M.
core +1 more source
Hemodynamic Profile of the Cardiotonic Agent Pimobendan
Pimobendan (UD-CG 115 BS) is a potent positive inotropic agent with vasodilatory properties. This hemodynamic profile was demonstrated in conscious rabbits chronically instrumented with Doppler flow probes. Pimobendan (10, 30, 100, and 300 micrograms/kg i.v.) increased cardiac output, stroke volume, heart rate, and mesenteric, renal, and hindquarter ...
J C, van Meel, W, Diederen
openaire +3 more sources
Resuscitation after experimental cardiac arrest. [PDF]
Thesis (M.A.)--Boston ...
Salvador, Richard Anthony
core +1 more source
A series of novel 4,5-dihydro-5-methyl-6-(2 or 4-substituted 7-quinazolinyl)-3(2H)-pyridazinones was synthesized and examined for cardiotonic activity in anesthetized dogs. The 4-substituted aminoquinazolines generally showed potent and long-lasting inotropic activity.
Y, Nomoto, H, Takai, T, Ohno, K, Kubo
openaire +3 more sources
Origins of Plant Derived Medicines [PDF]
This review article describes the origins of plant derived medicines that have been developed as a result of traditional knowledge being handed down from one generation to the next.
De Britto, A. John, Maridass, Muthia
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