Results 41 to 50 of about 3,273,209 (295)

Why has positive inotropy failed in chronic heart failure? Lessons from prior inotrope trials. [PDF]

open access: yes, 2019
Current pharmacological therapies for heart failure with reduced ejection fraction are largely either repurposed anti-hypertensives that blunt overactivation of the neurohormonal system or diuretics that decrease congestion.
Ahmad, T   +10 more
core   +2 more sources

An Evaluation of Traditional Persian Medicine for the Management of SARS-CoV-2

open access: yesFrontiers in Pharmacology, 2020
A new coronavirus causing severe acute respiratory syndrome (SARS-CoV-2) has emerged and with it, a global investigation of new antiviral treatments and supportive care for organ failure due to this life-threatening viral infection.
Roodabeh Bahramsoltani   +3 more
doaj   +1 more source

Evaluating the cancer therapeutic potential of cardiac glycosides [PDF]

open access: yes, 2014
Cardiac glycosides, also known as cardiotonic steroids, are a group of natural products that share a steroid-like structure with an unsaturated lactone ring and the ability to induce cardiotonic effects mediated by a selective inhibition of the Na(+)/K(+)
Burgos Morón, Estefanía   +5 more
core   +3 more sources

Correlation between endogenous polyamines in human cardiac tissues and clinical parameters in patients with heart failure [PDF]

open access: yes, 2016
This work was supported by a grant from the Instituto de Salud Carlos III(FISS03-1497), from which Clara Meana was recipient of a fellowships. CM, CB and LS designed and performed the biochemical experiments, JB designed and performed the experiments of ...
Bordallo Landa, Javier   +5 more
core   +2 more sources

Ion pumps as biological targets for decavanadate [PDF]

open access: yes, 2013
The putative applications of poly-, oligo- and mono-oxometalates in biochemistry, biology, pharmacology and medicine are rapidly attracting interest. In particular, these compounds may act as potent ion pump inhibitors and have the potential to play a ...
Aureliano, M.
core   +1 more source

Hemodynamic Profile of the Cardiotonic Agent Pimobendan

open access: yesJournal of Cardiovascular Pharmacology, 1989
Pimobendan (UD-CG 115 BS) is a potent positive inotropic agent with vasodilatory properties. This hemodynamic profile was demonstrated in conscious rabbits chronically instrumented with Doppler flow probes. Pimobendan (10, 30, 100, and 300 micrograms/kg i.v.) increased cardiac output, stroke volume, heart rate, and mesenteric, renal, and hindquarter ...
J C, van Meel, W, Diederen
openaire   +3 more sources

Resuscitation after experimental cardiac arrest. [PDF]

open access: yes, 1953
Thesis (M.A.)--Boston ...
Salvador, Richard Anthony
core   +1 more source

Studies on cardiotonic agents. VII. Potent cardiotonic agent KF15232 with myofibrillar Ca2+ sensitizing effect.

open access: yesChemical and Pharmaceutical Bulletin, 1991
A series of novel 4,5-dihydro-5-methyl-6-(2 or 4-substituted 7-quinazolinyl)-3(2H)-pyridazinones was synthesized and examined for cardiotonic activity in anesthetized dogs. The 4-substituted aminoquinazolines generally showed potent and long-lasting inotropic activity.
Y, Nomoto, H, Takai, T, Ohno, K, Kubo
openaire   +3 more sources

Origins of Plant Derived Medicines [PDF]

open access: yes, 2008
This review article describes the origins of plant derived medicines that have been developed as a result of traditional knowledge being handed down from one generation to the next.
De Britto, A. John, Maridass, Muthia
core   +1 more source

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