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Cardiovascular–kidney–metabolic (CKM) syndrome represents a continuum of interrelated adiposity, insulin resistance, cardiovascular disease, kidney dysfunction, and metabolic disturbances that evolve across the lifespan.
Aline M. A. de Souza +5 more
doaj +1 more source
Cardiovascular-kidney-metabolic (CKM) syndrome.
Cardiovascular-kidney-metabolic (CKM) syndrome recognises the connection between metabolic conditions (particularly obesity, diabetes and metabolic dysfunction-associated fatty liver disease), chronic kidney disease and cardiovascular disease. There is a high and growing prevalence of CKM syndrome. While genetic and epigenetic factors predispose to CKM
Dwyer, Karen M +3 more
openaire +1 more source
Purpose To determine whether diabetes mellitus is associated with higher systemic and hip‐specific complications and to evaluate reoperation rates after hip arthroscopy. Methods Using the TriNetX Research Network and Current Procedural Terminology and International Classification of Diseases codes, we identified diabetic and nondiabetic patients aged ...
Nicholas J. Morriss +3 more
wiley +1 more source
Rationale & Objectives: The cardiovascular-kidney-metabolic (CKM) syndrome is defined as the intricate interplay among metabolic risks, chronic kidney disease (CKD) and the cardiovascular system. The deteriorating CKM syndrome contributes to untimely
Zhejia Tian +5 more
doaj +1 more source
Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Thyroid hormones are involved in multiple metabolic pathways in the body and are essential for maintaining organ functions across the lifespan. Aging-related thyroid dysfunction has a bidirectional relationship with the development of chronic diseases ...
Hui Li +6 more
doaj +1 more source
Background: Cardiovascular, kidney, metabolic, and liver diseases are closely interconnected and frequently coexist. While the cardiovascular–kidney–metabolic (CKM) framework provides a unified model, increasing evidence supports a central role for ...
Khalid Aljohani +21 more
core +1 more source
Association of arterial stiffness with single nucleotide polymorphism rs1333049 and metabolic risk factors [PDF]
The electronic version of this article is the complete one and can be found online at: http://www.cardiab.com/content/12/1/93. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.
Veerapol Kukongviriyapan +23 more
core +1 more source
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić +7 more
wiley +1 more source
Background In 2023, the American Heart Association defined the concept of cardiovascular–kidney–metabolic (CKM) syndrome as a health disorder ascribed to connections among obesity, diabetes, chronic kidney disease, and cardiovascular disease.
Dingyuan Tu +4 more
doaj +1 more source

