Results 41 to 50 of about 9,254,128 (285)
A career in career - understanding what career looks like in the career development sector [PDF]
, 2017 There is little known about the careers workforce in the UK. This research focuses on developing a better understanding of who chooses to become a career development practitioner, their motivation, the transferable skills they bring with them and how ...
Neary, S. +2 more
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Quantitative analysis of socially regional development significant indicators
Ученые записки Российской академии предпринимательства, 2021 The article is devoted to the regional socio-economic and social development of Russian regions. The authors draw attention to recent trends in the study of these processes.
L. A. Tretyakova, E. V. Lisova
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Preparing Early Career Librarians for Leadership and Management: A Feminist Critique
In the Library with the Lead Pipe, 2019 In Brief This article explores the opportunities and challenges that early career librarians face when advancing their careers, desired qualities for leaders or managers of all career stages, and how early career librarians can develop those qualities ...
Camille Thomas, Elia Trucks, H.B. Kouns
doaj
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
The Civil Servants Career Development [PDF]
Theoretical and Applied Economics, 2009 The current economic and financial context, influenced by the crisis, as well as the need of meeting the European Union standards, make the permanent restructuring of the workforce, combined with career staff development an extremely important line of ...
Mihaela Comãnescu
doaj +1 more source
Perceived career development support in workplace career programme [PDF]
Ekonomski Anali, 2014 This study aims to quantify the relationship between the workplace career programme, perceived career development support, and job satisfaction. The survey method was employed to gather self-reported questionnaires from employees who work at a ...
Ismail Azman +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source