Results 91 to 100 of about 20,666 (222)

Upregulation of peroxisome proliferator-activated receptor gamma coactivator gene ( PGC1A ) during weight loss is related to insulin sensitivity but not to energy expenditure [PDF]

, 2018
Aims/hypothesis: We investigated whether skeletal muscle peroxisome proliferator-activated receptor gamma coactivator-1 (PGC1A; also known as PPARGC1A) and its target mitofusin-2 (MFN2), as well as carnitine palmitoyltransferase-1 (CPT1; also known as ...
Barthassat, V., Bobbioni-Harsch, E., Gastaldi, G., Giacobino, J.-P, Golay, A., Habicht, F., Muzzin, P., Russell, A.   +7 more
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Involvement of fatty acid synthase in dengue virus infection [PDF]

, 2017
BACKGROUND: The mosquito transmitted Dengue virus (DENV) remains a significant public health problem in many tropical and subtropical countries. Increasing evidence has suggested that during the infection process cellular lipids play important roles at ...
Duncan R. Smith, Janthima Jaresitthikunchai, Natthida Tongluan, Nitwara Wikan, Nuttaporn Wongsiriroj, Phitchayapak Wintachai, Sarawut Khongwichit, Sittiruk Roytrakul, Supoth Rajakam, Sutee Yoksan, Suwipa Ramphan   +10 more
core   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Preparació de 3-azidocumarines i derivats alquínics d’àcids grassos per reaccions “click”. [PDF]

, 2015
Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2015, Tutor: Jordi Garcia GómezClick chemistry is evolving as a powerful tool in biological applications because it allows the sensitive and specific detection of ...
Torralvo Martín, Héctor
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Development of NAFLD‐Specific Human Liver Organoid Models on a Microengineered Array Chip for Semaglutide Efficacy Evaluation

Cell Proliferation, EarlyView.
Microporous array organ chips were integrated with commercially available well plates to develop organoid chip platforms, which enable modelling of hepatic physiology and non‐alcoholic fatty liver disease (NAFLD) pathogenesis, as well as evaluation of semaglutide therapeutics. ABSTRACT Progressive non‐alcoholic fatty liver disease (NAFLD) may culminate
Xiao‐yan You, Xiang‐yang Li, Hui Wang, Guo‐ping Zhao   +3 more
wiley   +1 more source

Effects of food restriction on growth, body composition and gene expression related in regulation of lipid metabolism and food intake in grass carp [PDF]

, 2017
It is well known that most fish would prefer to use body lipid stores for energy expenditure when receiving a long-term food restriction. However, the mechanism of this is still not clear.
Chen, Weijun, Gong, Yulong, Han, Dong, Jin, Junyan, Liu, Haokun, Xie, Shouqi, Yang, Yunxia, Zhu, Xiaoming   +7 more
core   +1 more source

Carnitine Palmitoyltransferase 1 Increases Lipolysis, UCP1 Protein Expression and Mitochondrial Activity in Brown Adipocytes

PLoS ONE, 2016
The discovery of active brown adipose tissue (BAT) in adult humans and the fact that it is reduced in obese and diabetic patients have put a spotlight on this tissue as a key player in obesity-induced metabolic disorders. BAT regulates energy expenditure
M. Calderón-Domínguez, David Sebastián, R. Fucho, Minéia Weber, J. F. Mir, Ester García-Casarrubios, M. Obregon, A. Zorzano, Á. Valverde, D. Serra, Laura Herrero   +10 more
semanticscholar   +1 more source

The depletion of serine beta‐lactamase‐like protein (LACTB) ameliorates metabolic dysfunction–associated steatotic liver disease by reducing ubiquitin‐mediated degradation of carnitine palmitoyltransferase 2

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) represents one of the most common chronic liver disorders worldwide, and its incidence continues to rise each year. Serine β‐lactamase‐like protein (LACTB) is a serine protease that plays a crucial role in lipid metabolism and hepatocellular carcinoma, but its function in ...
Wujiang Shi, Xin Liu, Nan Wang, Qianwen Zhang, Jianjun Gao, Canghai Guan, Yapeng Li, Chengru Yang, Shaowu Bi, Xinlei Zou, Xiangyu Zhong   +10 more
wiley   +1 more source

β3-Adrenoceptor Mediates Metabolic Protein Remodeling in a Rabbit Model of Tachypacing-Induced Atrial Fibrillation

Cellular Physiology and Biochemistry, 2013
Background: The beta 3-adrenoceptor (β3-AR) is closely associated with energy metabolism. This study aimed to explore the role of β3-AR in energy remodeling in a rabbit model of pacing-induced atrial fibrillation (AF).
Yixi Liu, Jianqiang Geng, Yutan Liu, Yue Li, Jingxia Shen, Xingping Xiao, Li Sheng, Baofeng Yang, Cheping Cheng, Weimin Li   +9 more
doaj   +1 more source

CARNITINE PALMITOYLTRANSFERASE II DEFICIENY (CPT II) REFERENCES (MYOPATHY WITH DEFICIENCY OF CARNITINE PALMITOYLTRANSFERASE II; CPT II DEFICIENCY, MYOPATHIC; HYPOGLYCEMIA, HYPOKETOTIC, WITH DEFICIENCY OF CARNITINE PALMITOYLTRANSFERASE II; CPT DEFICIENCY, [PDF]

Mugica M, Rinaldo P.

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