Results 101 to 110 of about 20,666 (222)

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

The FEBS Journal, EarlyView.
Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna, Christoff Odendaal, Madhulika Singh, Albert Gerding, Miriam Langelaar‐Makkinje, Marianne van der Zwaag, Asmara Drachman, Vladimíra Cetkovská, Gaby Liem Foeng Kioen, Anne‐Claire M. F. Martines, Nicolette C. A. Huijkman, Hein Schepers, Bart van de Sluis, Dirk‐Jan Reijngoud, Ody C. M. Sibon, Amy C. Harms, Thomas Hankemeier, Barbara M. Bakker   +17 more
wiley   +1 more source

Effects of parental dietary linoleic acid on growth performance, antioxidant capacity, and lipid metabolism in domestic pigeons (Columba livia)

Poultry Science, 2020
The objective of this study was to evaluate the effects of dietary linoleic acid (LA) on growth performance, antioxidant capacity, and lipid metabolism in pigeon squabs by supplementing LA in their parental diets.
Q.Q. Xu, X.W. Ma, X.Y. Dong, Z.R. Tao, L.Z. Lu, X.T. Zou   +5 more
doaj   +1 more source

Maternal overnutrition impacts offspring adiposity and brain appetite markers-modulation by postweaning diet [PDF]

, 2010
Maternal obesity has long-term consequences for the development of hypothalamic neurones involved in energy homeostasis and the metabolic profile in offspring. In the present study, we compared the effects of maternal obesity induced by longstanding high-
Chen, H, Morris, MJ, Rajia, S
core   +1 more source

Fetal glucose availability: a key regulator of the metabolic, hormonal and contractility profiles of the fetal sheep heart

The Journal of Physiology, EarlyView.
Abstract figure legend To investigate the role of glucose availability in fetal left ventricle (LV) development, this study assessed whether maternal late gestation undernutrition (LGUN; 50% of Control diet) induced alterations in the contractility, metabolic, and hormonal profile can be ameliorated in LGUN fetuses receiving glucose infusion (LGUN+G ...
Melanie R. Bertossa, Jack R. T. Darby, Stacey L. Holman, Steven K. S. Cho, Ashley S. Meakin, Mitchell C. Lock, Jordan A. Minns, Michael D. Wiese, Christopher K. Macgowan, Mike Seed, Janna L. Morrison   +10 more
wiley   +1 more source

Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas

BMC Genomics, 2017
Background The Pacific oyster Crassostrea gigas is an important marine fishery resource, which contains high levels of glycogen that contributes to the flavor and the quality of the oyster.
Busu Li, Kai Song, Jie Meng, Li Li, Guofan Zhang   +4 more
doaj   +1 more source

Age-Related Changes in Serum Lipid Levels, Hepatic Morphology, Antioxidant Status, Lipid Metabolism Related Gene Expression and Enzyme Activities of Domestic Pigeon Squabs (Columba livia)

Animals, 2020
The objective of this study was to evaluate the age-related changes in antioxidant status and the lipid metabolism of pigeon squabs (Columba livia), by determining the BW, antioxidant indices, serum lipid levels, lipid metabolism-related enzyme ...
Qianqian Xu, Huaiyu Li, Wenting Zhou, Xiaoting Zou, Xinyang Dong   +4 more
doaj   +1 more source

Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells. [PDF]

, 2013
Work in our lab is supported by the Medical Research Council [New Investigator Research Grant G1100165 to CA] and Plymouth University [PhD studentship to JB] The final version of record is available at http://www.biochemj.org/bj/456/bj4560417.htmHigh ...
Affourtit, C, Barlow, J
core   +2 more sources

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

The Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga, Matheus B. Rocha, Ana P. Morelli, Raul G. da Costa, Marcelo A. S. Mori, Adelino S. R. da Silva, José R. Pauli, Dennys E. Cintra, Eduardo R. Ropelle   +8 more
wiley   +1 more source

Proteomics-Based Investigation of Different Live Prey Administered to Freshwater Dark Sleeper (Odontobutis potamophila): Examining the Effects on Glycolipids and Energy Metabolism

Metabolites
Live prey is characterized by balanced rich nutrients and high palatability and is widely used for the seedling cultivation of freshwater dark sleeper (Odontobutis potamophila) larvae.
Zihan Zhou, Qichen Jiang, You Zheng, Chen Hao, Shuyan Ding, Mengya Guo, Yunlong Zhao, Guoxing Liu, Shuyan Miao   +8 more
doaj   +1 more source

Estratègies de modulació de l'oxidació d'àcids grassos com a tractament per combatre l'obesitat [PDF]

, 2016
L'estil de vida actual, amb dietes d'alt contingut calòric i falta d'exercici físic, fa que la incidència d'obesitat s'incrementi notablement.
Calderón Domínguez, María, Fucho Salvador, Raquel, Herrero Rodríguez, Laura, Mir Bonnín, Joan Francesc, Serra i Cucurull, Dolors, Weber Blattes, Minéia   +5 more
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