Results 121 to 130 of about 20,666 (222)
Food Frontiers, Volume 7, Issue 2, March 2026.The study found that MAMP‐1 can alleviate lung injury by modulating the TLR4 signaling pathway to suppress LPS‐induced inflammation and promote cholesterol reverse transport. ABSTRACT Sepsis‐associated acute lung injury (SALI) significantly jeopardizes the health and survival prospects of neonates.
Shimei Lu +8 more
wiley +1 more source
Involvement of 5′AMP-Activated Protein Kinase (AMPK) in the Effects of Resveratrol on Liver Steatosis [PDF]
, 2018 This review focuses on the role of 5'-activated protein kinase (AMPK) in the effects of resveratrol (RSV) and some RSV derivatives on hepatic steatosis. In vitro studies, performed in different hepatic cell models, have demonstrated that RSV is effective
Eseberri Barace, Itziar +6 more
core +2 more sources
Journal of Biological Chemistry, 2015 Background: One interacting partner of the AMPA receptor (AMPAR) complex in the endoplasmic reticulum is carnitine palmitoyltransferase 1C (CPT1C).
Rut Fadó +7 more
semanticscholar +1 more source
Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes
Glia, Volume 74, Issue 3, March 2026.ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve +5 more
wiley +1 more source
Alisol A 24-Acetate Prevents Hepatic Steatosis and Metabolic Disorders in HepG2 Cells
Cellular Physiology and Biochemistry, 2016 Background: Non-alcoholic fatty liver disease (NAFLD) is closely associated with metabolic disorders including hepatic lipid accumulation and inflammation. Alisol A 24-acetate, a triterpene from Alismatis rhizome, has multiple biologic activities such as
Lu Zeng +6 more
doaj +1 more source
Deficiency of the purinergic receptor 2X7 attenuates nonalcoholic steatohepatitis induced by high-fat diet. possible role of the NLRP3 Inflammasome [PDF]
, 2017 Molecular mechanisms driving transition from simple steatosis to nonalcoholic steatohepatitis (NASH), a critical step in the progression of nonalcoholic fatty liver disease (NAFLD) to cirrhosis, are poorly defined. This study aimed at investigating the
Blasetti Fantauzzi, Claudia +6 more
core +3 more sources
Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis
Glia, Volume 74, Issue 3, March 2026.Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco +16 more
wiley +1 more source
Rosiglitazone ameliorates palmitic acid-induced cytotoxicity in TM4 Sertoli cells
Reproductive Biology and Endocrinology, 2018 The Sertoli cell is the only somatic cell within the seminiferous tubules, and is vital for testis development and spermatogenesis. Rosiglitazone (RSG) is a member of the thiazolidinedione family and is a peroxisome proliferator-activated receptor-γ ...
Xie Ge +9 more
doaj +1 more source
Neonatal Carnitine Palmitoyltransferase II Deficiency: A Lethal Entity.
Journal of clinical and diagnostic research : JCDR, 2015 Carnitine palmitoyltransferase II (CPTII) deficiency is a rare disorder of mitochondrial fatty acid oxidation with autosomal recessive mode of inheritance.
S. Malik +3 more
semanticscholar +1 more source
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source