Results 141 to 150 of about 20,666 (222)

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

open access: yesCell Proliferation, Volume 59, Issue 2, February 2026.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu   +5 more
wiley   +1 more source

Insights Into circRNA‐Mediated Lipid Metabolism in Cancer Progression

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Lipid metabolism reprogramming is one of the most prominent characteristics of cancer, but it is still unclear which regulatory pathways underlie this process in cancer cells. Circular RNAs (circRNAs) represent a novel category of non‐coding RNAs with multifaceted regulatory functions. While the biological roles of circRNAs in cancer have been
Zhiwei Miao   +4 more
wiley   +1 more source

Tks4‐Targeted Gene Therapy Inhibited White Adipocyte Hypertrophy in Mice

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Tks4 knockout or knockdown by AAV mediated shRNA both successfully restricted adipocyte hypertrophy in high fat diet. The reduction of TAG was validated by biochemistry and lipidomics analyses. This study suggested a potential of Tks4 targeted therapy in obesity intervention. ABSTRACT Obesity is one of the most prevalent public health issues worldwide,
Meng Tian   +5 more
wiley   +1 more source

Dietary corn starch dose-dependently enhances intestinal and hepatic health in largemouth bass (Micropterus salmoides)

open access: yesAquaculture Reports
The study aimed to investigate starch-induced hepatobiliary syndrome in juvenile largemouth bass. Six isonitrogenous diets (Con, CoS20, CoS40, CoS60, CoS80, CoS100) with corn starch substituting 0 %, 20 %, 40 %, 60 %, 80 %, and 100 % of wheat starch ...
Godfred Boateng Agyenim   +5 more
doaj   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles   +3 more
wiley   +1 more source

Proximal Tubule‐Specific Genetic Deficiency of PPARα Worsens Systemic Lipid and Glucose Metabolism During Fasting

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Proximal tubule‐specific PPARα knockout mouse (PPARαΔKPT) showed decreased lipid and glucose metabolism in the kidney during fasting. Metabolism in the other organs was increased, presumably as a means of compensating for the impaired kidney metabolism.
Daiki Aomura   +12 more
wiley   +1 more source

Bavachin ameliorates cisplatin-induced nephrotoxicity by enhancing mitochondrial β-oxidation and lipid metabolism through MFN2

open access: yesMolecular Medicine
Background Cisplatin-induced nephrotoxicity is a critical adverse reaction that restricts the clinical utilization of cisplatin. Alterations in fatty acid metabolism have been associated with the pathogenesis of cisplatin-induced nephrotoxicity, yet the ...
Shilu Luo   +5 more
doaj   +1 more source

Biogenesis of Organelles and Membrane Proteins. [PDF]

open access: yes, 1988
Harmey, Matthew A.   +3 more
core   +1 more source

Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice

open access: yesInternational Journal of Nanomedicine, 2015
Mei Xue,1,2,* Liang Zhang,3,* Ming-xing Yang,1 Wei Zhang,1 Xiu-min Li,1,2 Zhi-min Ou,1 Zhi-peng Li,1,2 Su-huan Liu,1 Xue-jun Li,1 Shu-yu Yang1 1Xiamen Diabetes Institute, the First Affiliated Hospital of Xiamen University, Xiamen, 2Department of ...
Xue M   +9 more
doaj  

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