Results 41 to 50 of about 20,666 (222)
Glucose Alters Per2 Rhythmicity Independent of AMPK, Whereas AMPK Inhibitor Compound C Causes Profound Repression of Clock Genes and AgRP in mHypoE-37 Hypothalamic Neurons. [PDF]
PLoS ONE, 2016 Specific neurons in the hypothalamus are regulated by peripheral hormones and nutrients to maintain proper metabolic control. It is unclear if nutrients can directly control clock gene expression. We have therefore utilized the immortalized, hypothalamic
Johanneke E Oosterman, Denise D Belsham
doaj +1 more source
Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue [PDF]
, 2007 In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis).
Bianco, Antonio C. +12 more
core +1 more source
Fishes, 2022 Arachidonic acid (ARA, 20:4n-6) fed to Seriola dorsalis juveniles at different levels was evaluated. After a seven-week feeding trial, growth performance, hepatopancreas and muscle fatty acid (FA) composition, expression of lipid-relevant genes, and ...
Bruno Cavalheiro Araújo +6 more
doaj +1 more source
Mitochondrial fatty acid oxidation in obesity [PDF]
, 2014 Significance: Current lifestyles with high-energy diets and little exercise are triggering an alarming growth in obesity. Excess of adiposity is leading to severe increases in associated pathologies, such as insulin resistance, type 2 diabetes ...
Herrero Rodríguez, Laura +4 more
core +2 more sources
Molecules, 2019 Delphinidin-3-O-β-glucoside (D3G) is a health-promoting anthocyanin whose anti-obesity activity has not yet been thoroughly investigated. We examined the effects of D3G on adipogenesis and lipogenesis in 3T3-L1 adipocytes and primary white ...
Miey Park, Anshul Sharma, Hae-Jeung Lee
doaj +1 more source
Cancer & Metabolism, 2022 Background Altered lipid metabolism is closely related to the occurrence and development of hepatocellular carcinoma (HCC). Carnitine palmitoyltransferase 1C (CPT1C) is a member of CPT1 family and plays a key role in cancer development and progression ...
Ting Zhang +6 more
doaj +1 more source
Effect of Camellia Oil on Lipid Metabolism of HepG2 Cells Induced by Free Fatty Acids
Shipin gongye ke-ji, 2023 Objective: To evaluate the effects of camellia oil on lipid metabolism in free fatty acid-induced HepG2 hepatocytes. Methods: To screen the optimal concentration of action, the effect of camellia oil on HepG2 activity was assessed by CCK-8 assay.
Caihong XU +4 more
doaj +1 more source
Drug-Induced Inhibition of Mitochondrial Fatty Acid Oxidation and Steatosis [PDF]
, 2013 Mitochondrial Dysfunction and Diseases (H Jaeschke, Section Editor)International audienceDrug-induced inhibition of mitochondrial fatty acid β-oxidation (mtFAO) is a key mechanism whereby drugs can induce steatosis.
Begriche, Karima +5 more
core +4 more sources
PLoS Biology, 2018 It has been suggested that some cancer cells rely upon fatty acid oxidation (FAO) for energy. Here we show that when FAO was reduced approximately 90% by pharmacological inhibition of carnitine palmitoyltransferase I (CPT1) with low concentrations of ...
Cong-Hui Yao +5 more
semanticscholar +1 more source
Do the Effects of Resveratrol on Thermogenic and Oxidative Capacities in IBAT and Skeletal Muscle Depend on Feeding Conditions? [PDF]
, 2018 The aim of this study was to compare the effects of mild energy restriction and resveratrol on thermogenic and oxidative capacity in interscapular brown adipose tissue (IBAT) and in skeletal muscle.
Aguirre López, Leixuri +5 more
core +3 more sources