Results 61 to 70 of about 20,666 (222)

Icariin Alleviates Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome by Improving Liver Fatty Acid Oxidation and Inhibiting Lipid Accumulation

Molecules, 2023
(1) Background: Icariin is the main component of the Chinese herb Epimedium. A number of studies have shown that it alleviates abnormal lipid metabolism.
Yang Hai, Ling Zuo, Meng Wang, Ruoyu Zhang, Munan Wang, Li Ren, Congwen Yang, Jianwei Wang   +7 more
doaj   +1 more source

Estratègies de modulació de l'oxidació d'àcids grassos com a tractament per combatre l'obesitat [PDF]

, 2015
L'estil de vida actual, amb dietes d'alt contingut calòric i falta d'exercici físic, fa que la incidència d'obesitat s'incrementi notablement.
Calderón-Domínguez, María, Herrero Rodríguez, Laura, Mir, Joan Francesc, Serra, Dolors, Weber Blattes, Minéia   +4 more
core  

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice [PDF]

, 2003
Adiponectin has recently been shown to be a promising candidate for the treatment of obesity-associated metabolic syndromes. Replenishment of recombinant adiponectin in mice can decrease hyperglycemia, reverse insulin resistance, and cause sustained ...
Adachi, Baraona, Bijleveld, Campfield, Combs, Diehl, Funabiki, Guzman, Hill, Hotta, Kubota, Kudo, Lindros, McClain, Molina, Ouchi, Ouchi, Piot, Siler, Wilkes, Winder, Yokota   +21 more
core   +2 more sources

Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition–resistant triple-negative breast cancer cells

Journal of Biological Chemistry, 2019
Triple-negative breast cancers (TNBCs) lack progesterone and estrogen receptors and do not have amplified human epidermal growth factor receptor 2, the main therapeutic targets for managing breast cancer.
Larissa Menezes dos Reis, Douglas Adamoski, Rodolpho Ornitz Oliveira Souza, Carolline Fernanda Rodrigues Ascenção, Krishina Ratna Sousa de Oliveira, Felipe Corrêa-da-Silva, Fábio Malta de Sá Patroni, Marília Meira Dias, S. Consonni, Pedro Manoel Mendes de Moraes-Vieira, A. Silber, S. M. Dias   +11 more
semanticscholar   +1 more source

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation [PDF]

, 2015
Lipid overload in obesity and type 2 diabetes is associated with adipocyte dysfunction, inflammation, macrophage infiltration, and decreased fatty acid oxidation (FAO). Here, we report that the expression of carnitine palmitoyltransferase 1A (CPT1A), the
Belén Peral, Dolors Serra, Francesc Villarroya, Joan Francesc Mir, Joan J Vendrell, Laia Salvadó, Laura Herrero, Lorea Valcarcel, Manuel Vázquez-Carrera, Maria Ida Malandrino, María Calderon-Dominguez, María Gómez-Serrano, Minéia Weber, Núria Casals, Raquel Fucho, Sonia Fernández-Veledo, Xavier Escoté   +16 more
core   +2 more sources

Overview of Encapsulated Lysine and Methionine and Their Impacts on Transition Cow Performance and Health

Animal Research and One Health, EarlyView.
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem, Samy A. Elsaadawy, Zhaohai Wu, Lu Ma, Todd R. Callaway, Dengpan Bu   +5 more
wiley   +1 more source

Open-label clinical trial of bezafibrate treatment in patients with fatty acid oxidation disorders in Japan [PDF]

, 2018
IntroductionFatty acid oxidation disorders (FAODs) are rare diseases caused by defects in mitochondrial fatty acid oxidation (FAO) enzymes. While the efficacy of bezafibrate, a peroxisome proliferator-activated receptor agonist, on the in vitro FAO ...
Asahina Naoko, Fukao Toshiyuki, Hamada Yusuke, Hayashi Hiroshi, Ishige Mika, Isoe Toshiyuki, Kawakami Sanae, Kuzume Kazuyo, Miyakoshi Takashi, Nakamagoe Kiyotaka, Oba Koji, Ochi Fumihiro, Oki Eishin, Ono Kota, Sakai Norio, Sameshima Koji, Sato Norihiro, Shiraishi Hideaki, Tamaoka Akira, Watanabe Asami, Watanabe Kenji, Yamada Kenji, Yamaguchi Seiji, Yokoshiki Saki, 中馬越 清隆, 玉岡 晃   +25 more
core   +2 more sources

Fatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancer

Cell Death and Disease, 2016
Tumor cells exhibit unique metabolic adaptations that are increasingly viewed as potential targets for novel and specific cancer therapies. Among these targets, the carnitine palmitoyltransferase system is responsible for delivering the long-chain fatty ...
Q. Qu, F. Zeng, Xiaoju Liu, Q. Wang, Feihong Deng   +4 more
semanticscholar   +1 more source

Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study [PDF]

, 2018
Since sperm require high energy levels to perform their specialised function, it is vital that essential nutrients are available for spermatozoa when they develop, capacitate and acquire motility.
Agarwal, A., Antonini, G., Busetto, G. M., De Berardinis, E., Del Giudice, F., Gentile, V., Micic, S., Ragonesi, G., Virmani, A.   +8 more
core   +1 more source