Results 1 to 10 of about 6,494 (159)
Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation
Antioxidants, 2021 Carnosine is a dipeptide synthesized in the body from β-alanine and L-histidine. It is found in high concentrations in the brain, muscle, and gastrointestinal tissues of humans and is present in all vertebrates.
Ivana Jukic +2 more
exaly +3 more sources
Exercise and β-alanine supplementation on carnosine-acrolein adduct in skeletal muscle
Redox Biology, 2018 Previous studies have demonstrated that exercise results in reactive aldehyde production and that β-alanine supplementation increases carnosine content in skeletal muscle.
Luana Farias de Oliveira +2 more
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Biomedicines, 2021 Carnosine is a natural occurring endogenous dipeptide that was proposed as an anti-aging agent more than 20 years ago. Carnosine can be found at low millimolar concentrations at brain level and different preclinical studies have demonstrated its ...
Giuseppe Caruso +2 more
exaly +3 more sources
Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model
Molecular Cancer, 2010 Background It was previously demonstrated that the dipeptide carnosine inhibits growth of cultured cells isolated from patients with malignant glioma.
Frank Gaunitz
exaly +3 more sources
Cells, 2019 Carnosine (β-alanyl-L-histidine), a dipeptide, is an endogenous antioxidant widely distributed in excitable tissues like muscles and the brain. Carnosine is involved in cellular defense mechanisms against oxidative stress, including the inhibition ...
Giuseppe Caruso +2 more
exaly +3 more sources
Effect of histidine and carnosine on haemoglobin recovery in anaemia induced-kidney damage and iron-loading mouse models [PDF]
Amino AcidsHistidine and carnosine can form complexes with divalent metal ions such as Fe2+, potentially providing stability to intracellular labile iron.
Mayra Vera-Aviles +4 more
doaj +2 more sources
Slovenian Veterinary Research, 2023 Metabolic syndrome is a crucial health challenge, and the available therapeutic agents are still not effective. Carnosine, a cytoplasmic dipeptide, is a potent anti-glycation, anti-oxidant, anti-inflammatory and chelating agent.
Amany I Ahmed +4 more
doaj +1 more source
Molecules, 2022 The activity of the P-glycoprotein (P-gp) transporter encoded by the ABCB1 gene confers resistance to anticancer drugs and contributes to cancer-related mortality and morbidity.
Mohamed A. Morsy +7 more
doaj +1 more source
Thermodynamic and voltammetric study on carnosine and ferrocenyl-carnosine
Dalton Transactions, 2023 An electroactive carnosine derivative (ferrocenyl-carnosine, FcCAR (L)) was synthesized and its complexing and sensing properties were evaluated; it was found to be promising for the electrochemical detection of Hg2+and Pb2+in an aqueous environment.
Chiara Abate +6 more
openaire +3 more sources
Regulation of mitochondrial function and energy metabolism: A primary mechanism of cytoprotection provided by carnosine [PDF]
Trends in Pharmaceutical Sciences, 2018 Carnosine is an abundantly found dipeptide present in different tissues. Several pharmacological properties have been attributed to carnosine. On the other hand, the precise mechanism of cytoprotection provided by carnosine remains obscure.
Reza Heidari +4 more
doaj +3 more sources