Results 51 to 60 of about 22,312 (304)

Carnosine Catalyzes the Formation of the Oligo/Polymeric Products of Methylglyoxal

Cellular Physiology and Biochemistry, 2018
Background/Aims: Reactive dicarbonyl compounds, such as methylglyoxal (MG), contribute to diabetic complications. MG-scavenging capacities of carnosine and anserine, which have been shown to mitigate diabetic nephropathy, were evaluated in vitro and in ...
Tim Weigand, Benjamin Singler, Thomas Fleming, Peter Nawroth, Karel D. Klika, Christian Thiel, Hans Baelde, Sven F. Garbade, Andreas H. Wagner, Markus Hecker, Benito A. Yard, Albert Amberger, Johannes Zschocke, Claus P. Schmitt, Verena Peters   +14 more
doaj   +1 more source

Dietary interventions to contrast the onset and progression of diabetic nephropathy. a critical survey of new data [PDF]

, 2017
This article is a critical overview of recent contributions on the dietary corrections and the foods that have been claimed to delay or hinder the onset of diabetic nephropathy (DN) and its progression to end-stage renal disease.
Iacobini, Carla, Menini, Stefano, Pesce, Carlo, Pugliese, Giuseppe   +3 more
core   +1 more source

The ergogenic effect of acute carnosine and anserine supplementation: dosing, timing, and underlying mechanism

Journal of the International Society of Sports Nutrition, 2022
Background Recent studies suggest that acute-combined carnosine and anserine supplementation has the potential to improve the performance of certain cycling protocols.
S. de Jager, L. Blancquaert, Thibaux Van der Stede, E. Lievens, S. De Baere, S. Croubels, E. Gilardoni, L. Regazzoni, G. Aldini, J. Bourgois, W. Derave   +10 more
semanticscholar   +1 more source

Muscle carnosine in experimental autoimmune encephalomyelitis and multiple sclerosis [PDF]

, 2018
BACKGROUND: Muscle carnosine is related to contractile function (Ca++ handling) and buffering of exercise-induced acidosis. As these muscular functions are altered in Multiple Sclerosis (MS) it is relevant to understand muscle carnosine levels in MS ...
Blancquaert, Laura, Derave, Wim, Eijnde, Bert O, Keytsman, Charly, Missinne, Maarten, Van Noten, Pieter, Vandenabeele, Frank, Wens, Inez   +7 more
core   +2 more sources

Oral Supplementation with L-Carnosine Attenuates Social Recognition Deficits in CD157KO Mice via Oxytocin Release

Nutrients, 2022
The outcomes of supplementation with L-carnosine have been investigated in clinical trials in children with autism spectrum disorder (ASD). However, reports on the effects of L-carnosine in humans have been inconsistent, and the efficacy of L-carnosine ...
T. Tsuji, Kazumi Furuhara, M. Gerasimenko, A. Shabalova, Stanislav M. Cherepanov, Kana Minami, H. Higashida, C. Tsuji   +7 more
semanticscholar   +1 more source

Exercise and β-alanine supplementation on carnosine-acrolein adduct in skeletal muscle

Redox Biology, 2018
Previous studies have demonstrated that exercise results in reactive aldehyde production and that β-alanine supplementation increases carnosine content in skeletal muscle.
Victor H. Carvalho, Ana H.S. Oliveira, Luana F. de Oliveira, Rafael P. da Silva, Paolo Di Mascio, Bruno Gualano, Guilherme G. Artioli, Marisa H.G. Medeiros   +7 more
doaj   +1 more source

Impaired nutrient signaling and body weight control in a Na⁺ neutral amino acid cotransporter (Slc6a19)-deficient mouse [PDF]

, 2015
Amino acid uptake in the intestine and kidney is mediated by a variety of amino acid transporters. To understand the role of epithelial neutral amino acid uptake in whole body homeostasis, we analyzed mice lacking the apical broad-spectrum neutral (0 ...
Bailey, Charles G., Bröer, Angelika, Bröer, Stefan, Holst, Jeff, Juelich, Torsten, Rasko, John E J, Solomon, Peter S, Tietze, Nadine, Vanslambrouck, Jessica M   +8 more
core   +1 more source

Thai Native Chicken as a Potential Functional Meat Source Rich in Anserine, Anserine/Carnosine, and Antioxidant Substances

Animals, 2021
Simple Summary Potential bioactive compounds are properties that can play an important role in the prevention of chronic diseases, exhibit neuroprotective effects, and have antioxidant, anti-aging, and antiglycation properties.
S. Charoensin, B. Laopaiboon, W. Boonkum, Jutarop Phetcharaburanin, Myra O. Villareal, H. Isoda, M. Duangjinda   +6 more
semanticscholar   +1 more source

Carnosine Supplementation Enhances Post Ischemic Hind Limb Revascularization

Frontiers in Physiology, 2019
High (millimolar) concentrations of the histidine containing dipeptide – carnosine (β-alanine-L-histidine) are present in the skeletal muscle. The dipeptide has been shown to buffer intracellular pH, chelate transition metals, and scavenge lipid ...
Adjoa A. Boakye, Deqing Zhang, Deqing Zhang, Luping Guo, Luping Guo, Yuting Zheng, Yuting Zheng, David Hoetker, David Hoetker, Jingjing Zhao, Jingjing Zhao, Dheeraj Kumar Posa, Dheeraj Kumar Posa, Chin K. Ng, Huaiyu Zheng, Amit Kumar, Vijay Kumar, Michael F. Wempe, Aruni Bhatnagar, Aruni Bhatnagar, Daniel J. Conklin, Daniel J. Conklin, Shahid P. Baba, Shahid P. Baba   +23 more
doaj   +1 more source

Carnosine inhibits the proliferation of human gastric cancer SGC-7901 cells through both of the mitochondrial respiration and glycolysis pathways. [PDF]

PLoS ONE, 2014
Carnosine, a naturally occurring dipeptide, has been recently demonstrated to possess anti-tumor activity. However, its underlying mechanism is unclear.
Yao Shen, Jianbo Yang, Juan Li, Xiaojie Shi, Li Ouyang, Yueyang Tian, Jianxin Lu   +6 more
doaj   +1 more source