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The biosynthesis of carotenes

Archives of Biochemistry and Biophysics, 1962
Abstract A body of factual information has accumulated during the past decade which, in general, supports or is compatible with the proposal of Porter and Lincoln on the mechanism of biosynthesis of carotenes. However, some information has been obtained which necessitates a revision in details of the proposed scheme.
J W, PORTER, D G, ANDERSON
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THE PYROLYSIS OF CAROTENE

Canadian Journal of Research, 1948
Kuhn and Winterstein reported the isolation of 2,6-dimethylnaphthalene from the products of pyrolysis of carotenoid pigments. The production of alkyl derivatives of phenanthrene and chrysene by the same type of cyclization can readily be formulated.
R N, JONES, R W, SHARPE
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Formation of Carotene in vitro

Nature, 1960
RESULTS presented in this communication indicate that both β-hydroxy β-methylglutarate and mevalonate may be considered precursors of carotene formation in an in vitro extract obtained from mycelial mats of the mould Phycomyces blakesleeanus. This extract, capable of synthesizing carotene, can also be used for establishing the existence of a back ...
H, YOKOYAMA   +2 more
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CAROTENE BIOSYNTHESIS IN FUNGI

Pure and Applied Chemistry, 1973
Abstract
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The toxicity of beta-carotene

Toxicology, 1985
The safety of beta-carotene, a widely distributed food colorant was assessed in tests with cells and in sub-chronic and chronic experiments with animals. Mutagenicity evaluations which included the standard Ames test and the micro-nucleus test of bone marrow cells from mice showed that beta-carotene exerted no mutagenic properties.
R, Heywood   +3 more
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The Beta-Carotene Story

2001
Considered to be an effective antioxidant, beta-carotene, a carotenoid that occurs naturally in many vegetables and fruits and that converts to vitamin A in the body, has been the subject of intensive cancer prevention research for decades,1; and is a commonly found supplement on the shelves of most supermarkets.
P, Greenwald, S S, McDonald
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