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Imaging of articular cartilage
We tried to review the role of magnetic resonance imaging (MRI) in understanding microscopic and morphologic structure of the articular cartilage. The optimal protocols and available spin-echo sequences in present day practice are reviewed in context of ...
Bhawan K Paunipagar, DD Rasalkar
doaj +3 more sources
Focal lesions of articular cartilage give rise to pain and reduced joint function and may, if left untreated, lead to osteoarthritis. Implantation of in vitro generated, scaffold-free autologous cartilage discs may represent the best treatment option ...
Nadine Frerker+9 more
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Low-intensity pulsed ultrasound promotes mesenchymal stem cell transplantation-based articular cartilage regeneration via inhibiting the TNF signaling pathway [PDF]
Background: Mesenchymal stem cell (MSC) transplantation therapy is highly investigated for the regenerative repair of cartilage defects. Low-intensity pulsed ultrasound (LIPUS) has the potential to promote chondrogenic differentiation of MSCs. However, its underlying mechanism remains unclear.
arxiv +1 more source
Vitrification of particulated articular cartilage via calculated protocols
Preserving viable articular cartilage is a promising approach to address the shortage of graft tissue and enable the clinical repair of articular cartilage defects in articulating joints, such as the knee, ankle, and hip.
Kezhou Wu+4 more
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CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes. [PDF]
To examine the role of connective tissue growth factor CCN2/CTGF (CCN2) in the maintenance of the articular cartilaginous phenotype, we analyzed knee joints from aging transgenic mice (TG) overexpressing CCN2 driven by the Col2a1 promoter.
Shinsuke Itoh+6 more
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The mechanical properties of biological tissues influence their function and can predict degenerative conditions before gross histological or physiological changes are detectable. This is especially true for structural tissues such as articular cartilage,
Katherine M. Arnold+3 more
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THE PERMEABILITY OF ARTICULAR CARTILAGE [PDF]
1. We have shown that the permeability of cartilage is the same in necropsy specimens as in the living animal. We have concluded that studies of material transport into cartilage carried out on necropsy specimens validly reflect in vivo conditions. 2. We have studied the effect of agitation of the fluid in which cartilage is immersed upon the rate of
Alice Maroudas+3 more
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Influence of collagen fibre orientation on the frictional properties of articular cartilage
Articular cartilage has a unique collagen fibre network structure that exhibits both anisotropy and depth dependency. Collagen fibre orientation in a cross‐section parallel to the articular cartilage surface may affect the lubrication properties of ...
Seido Yarimitsu+2 more
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During the development of the appendicular skeleton, the cartilaginous templates undergo hypertrophic differentiation and remodels into bone, except for the cartilage most adjacent to joint cavities where hypertrophic differentiation and endochondral ...
Michael Chau+9 more
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Lubrication of articular cartilage [PDF]
A mix of proteins, polymers, lipids, and tightly bound but fluid shells of water molecules may account for a healthy joint’s ultralow friction.
Jahn, Sabrina, Klein, Jacob
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