Effects of Articular Cartilage Constituents on Phosphotungstic Acid Enhanced Micro-Computed Tomography [PDF]
Contrast-enhanced micro-computed tomography (CE mu CT) with phosphotungstic acid (PTA) has shown potential for detecting collagen distribution of articular cartilage.
Finnilä, Mikko A.+8 more
core +10 more sources
Imaging of articular cartilage
AbstractWe tried to review the role of magnetic resonance imaging (MRI) in understanding microscopic and morphologic structure of the articular cartilage. The optimal protocols and available spin-echo sequences in present day practice are reviewed in context of common pathologies of articular cartilage.
Darshana D. Rasalkar+1 more
openaire +4 more sources
Lubrication of articular cartilage [PDF]
A mix of proteins, polymers, lipids, and tightly bound but fluid shells of water molecules may account for a healthy joint’s ultralow friction.
Jahn, Sabrina, Klein, Jacob
openaire +1 more source
THE PERMEABILITY OF ARTICULAR CARTILAGE [PDF]
1. We have shown that the permeability of cartilage is the same in necropsy specimens as in the living animal. We have concluded that studies of material transport into cartilage carried out on necropsy specimens validly reflect in vivo conditions. 2. We have studied the effect of agitation of the fluid in which cartilage is immersed upon the rate of
Alice Maroudas+3 more
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Human stem cells and articular cartilage regeneration. [PDF]
The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki+2 more
core +4 more sources
Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage [PDF]
Primary cilia are slender, microtubule based structures found in the majority of cell types with one cilium per cell. In articular cartilage, primary cilia are required for chondrocyte mechanotransduction and the development of healthy tissue.
Irianto, J+3 more
core +1 more source
Cell sources for articular cartilage repair strategies: shifting from mono-cultures to co-cultures [PDF]
The repair of articular cartilage is challenging due to the sparse native cell population combined with the avascular and aneural nature of the tissue. In recent years cartilage tissue engineering has shown great promise.
Blitterswijk, C.A. van+4 more
core +3 more sources
Development of a peptide-siRNA nanocomplex targeting NF- κB for efficient cartilage delivery [PDF]
Delivery of therapeutic small interfering RNAs (siRNAs) in an effective dose to articular cartilage is very challenging as the cartilage dense extracellular matrix renders the chondrocytes inaccessible, even to intra-articular injections. Herein, we used
Akk, Antonina+7 more
core +3 more sources
Cryopreservation of articular cartilage
Cryopreservation has numerous practical applications in medicine, biotechnology, agriculture, forestry, aquaculture and biodiversity conservation, with huge potentials for biological cell and tissue banking. A specific tissue of interest for cryopreservation is the articular cartilage of the human knee joint for two major reasons: (1) clinically, there
Abazari, Alireza+3 more
openaire +2 more sources
A review of the differences between normal and osteoarthritis articular cartilage in human knee and ankle joints [PDF]
Background: Osteoarthritis (OA) is the most common joint disease yet its pathophysiology is still poorly understood. It is more prevalent in some lower limb joints than others; in particular the knee is more commonly affected than the ankle.
Beeson, Paul+2 more
core +1 more source