Results 21 to 30 of about 295,632 (299)

Cartilage proteoglycans [PDF]

Seminars in Cell & Developmental Biology, 2001
The predominant proteoglycan present in cartilage is the large chondroitin sulfate proteoglycan 'aggrecan'. Following its secretion, aggrecan self-assembles into a supramolecular structure with as many as 50 monomers bound to a filament of hyaluronan.
C B, Knudson, W, Knudson
openaire   +2 more sources

Optimal conditions of collagenase treatment for isolation of articular chondrocytes from aged human tissues

Regenerative Therapy, 2017
Introduction: There are various types of cartilage, including the auricular and articular cartilages. These cartilages have different functions, and their matrix volume and density of chondrocytes may differ.
Kazumichi Yonenaga, Satoru Nishizawa, Takumi Nakagawa, Yuko Fujihara, Yukiyo Asawa, Atsuhiko Hikita, Tsuyoshi Takato, Kazuto Hoshi   +7 more
doaj   +1 more source

New trends in articular cartilage repair

Journal of Experimental Orthopaedics, 2015
Damage to the articular cartilage is an important, prevalent, and unsolved clinical issue for the orthopaedic surgeon. This review summarizes innovative basic research approaches that may improve the current understanding of cartilage repair processes ...
Magali Cucchiarini, Christel Henrionnet, Didier Mainard, Astrid Pinzano, Henning Madry   +4 more
doaj   +1 more source

NF-κB/TWIST1 Mediates Migration and Phagocytosis of Macrophages in the Mice Model of Implant-Associated Staphylococcus aureus Osteomyelitis

Frontiers in Microbiology, 2020
Staphylococcus aureus (S. aureus) infection-induced osteomyelitis is a great challenge in clinic treatment. Identification of the essential genes and biological processes that are specifically changed in mononuclear cells at an early stage of S.
Yutian Wang, Yutian Wang, Yihuang Lin, Yihuang Lin, Caiyu Cheng, Caiyu Cheng, Pengyu Chen, Pengyu Chen, Ping Zhang, Hangtian Wu, Hangtian Wu, Kaiqun Li, Kaiqun Li, Ye Deng, Ye Deng, Jikun Qian, Jikun Qian, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +20 more
doaj   +1 more source

Biomimetic sulphated alginate hydrogels suppress IL-1β-induced inflammatory responses in human chondrocytes [PDF]

European Cells & Materials, 2017
Loss of articular cartilage from ageing, injury or degenerative disease is commonly associated with inflammation, causing pain and accelerating degradation of the cartilage matrix.
Ø Arlov, E Öztürk, M Steinwachs, G Skjåk-Bræk, M Zenobi-Wong   +4 more
doaj   +1 more source

Apolipoprotein E deficiency potentiates macrophage against Staphylococcus aureus in mice with osteomyelitis via regulating cholesterol metabolism

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionStaphylococcus aureus (S. aureus) osteomyelitis causes a variety of metabolism disorders in microenvironment and cells. Defining the changes in cholesterol metabolism and identifying key factors involved in cholesterol metabolism disorders ...
Mincheng Lu, Mincheng Lu, Ruiyi He, Ruiyi He, Chao Li, Chao Li, Zixian Liu, Zixian Liu, Yuhui Chen, Yuhui Chen, Bingsheng Yang, Bingsheng Yang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source

Early Stage Foreign Body Reaction against Biodegradable Polymer Scaffolds Affects Tissue Regeneration during the Autologous Transplantation of Tissue-Engineered Cartilage in the Canine Model

Cell Transplantation, 2012
To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with a greater firmness and a 3D structure.
Yukiyo Asawa, Tomoaki Sakamoto, Makoto Komura, Makoto Watanabe, Satoru Nishizawa, Yutaka Takazawa, Tsuyoshi Takato, Kazuto Hoshi M.D., Ph.D.   +7 more
doaj   +1 more source

Antenatal Corticosteroid Therapy Attenuates Angiogenesis Through Inhibiting Osteoclastogenesis in Young Mice

Frontiers in Cell and Developmental Biology, 2020
Antenatal corticosteroid therapy (ACT) has been shown to reduce morbidity and mortality rates in preterm delivery, but the fetus is more likely to face the risk of low bone mineralization and low fetal linear growth.
Yu Chai, Yu Chai, Jianwen Su, Jianwen Su, Weisheng Hong, Weisheng Hong, Runjiu Zhu, Runjiu Zhu, Caiyu Cheng, Caiyu Cheng, Lei Wang, Lei Wang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source

How to salvage the delivery of a wrong-sided meniscal allograft: A rare case series

Journal of Cartilage & Joint Preservation, 2021
Introduction: Although rare, tissue processing errors have occurred during meniscal transplantation. The anatomic differences between the lateral and medial menisci makes this problematic for surgeons who find themselves with an incorrectly labeled graft.
Andrew Gudeman, Iain Murray, Seth L. Sherman, Jack Farr   +3 more
doaj   +1 more source

Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis

Journal of Cartilage & Joint Preservation
Introduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear.
Yusuf Mufti, Jared P. Sachs, Andrew S. Bi, Chloe Franzia, John Ebersole, Taylor Giordano, Brian J. Cole   +6 more
doaj   +1 more source