Results 21 to 30 of about 707,817 (385)
Induction of WNT16 via peptide-mRNA nanoparticle-based delivery maintains cartilage homeostasis [PDF]
, 2020 Osteoarthritis (OA) is a progressive joint disease that causes significant disability and pain and for which there are limited treatment options. We posit that delivery of anabolic factors that protect and maintain cartilage homeostasis will halt or ...
Akk, Antonina +6 more
core +2 more sources
Journal of the American Academy of Orthopaedic Surgeons, 2013 Cartilage damaged by trauma has a limited capacity to regenerate. Current methods of managing small chondral defects include palliative treatment with arthroscopic débridement and lavage, reparative treatment with marrow-stimulation techniques (eg, microfracture), and restorative treatment, including osteochondral grafting and autologous chondrocyte ...
Rocky S, Tuan +2 more
openaire +2 more sources
Arthroscopic Treatment of Cartilage Lesions With Microfracture and BST-CarGel
Arthroscopy Techniques, 2014 Bone marrow stimulation techniques for the treatment of articular cartilage defects such as microfracture so far have solely reproduced mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm ...
Matthias R. Steinwachs, M.D. +2 more
doaj +1 more source
Journal of Extracellular Vesicles, 2020 Articular cartilage has limited self-regenerative capacity and the therapeutic methods for cartilage defects are still dissatisfactory in clinic.
Hongxing Hu +8 more
semanticscholar +1 more source
Inhibition of NADPH Oxidases Prevents the Development of Osteoarthritis
Antioxidants, 2022 Increased oxidative stress in osteoarthritis (OA) cartilage mediates catabolic signal transduction leading to extracellular matrix degradation and chondrocyte apoptosis.
Jin Han +3 more
doaj +1 more source
Self-diffusion of polymers in cartilage as studied by pulsed field gradient NMR [PDF]
, 2002 Pulsed field gradient (PFG) nuclear magnetic resonance (NMR) was used to investigate the self-diffusion behaviour of polymers in cartilage. Polyethylene glycol and dextran with different molecular weights and in different concentrations were used as ...
Arnold, K. +5 more
core +2 more sources
A Synthetic Hydrogel Composite with the Mechanical Behavior and Durability of Cartilage
Advanced Functional Materials, 2020 This article reports the first hydrogel with the strength and modulus of cartilage in both tension and compression, and the first to exhibit cartilage‐equivalent tensile fatigue strength at 100 000 cycles.
Feichen Yang +6 more
semanticscholar +1 more source
Scientific Reports, 2017 Cartilage tissue is avascular and hypoxic which regulates chondrocyte phenotype via stabilization of HIFs. Here, we investigated the role of hypoxia and HIFs in regulation of Rho and canonical Wnt signaling in chondrocytes.
Ece Öztürk +4 more
doaj +1 more source
Mini-open Subpectoral Biceps Tenodesis Using All-Suture Anchor
Arthroscopy Techniques, 2020 The proximal biceps tendon is a common source of shoulder pain and dysfunction. When patients continue to have pain after exhaustive nonoperative treatment, the long head of the biceps tendon can be effectively treated with a tenotomy or tenodesis ...
Abbott Gifford +4 more
doaj +1 more source
Extracellular Vesicles: A Potential Biomarker for Quick Identification of Infectious Osteomyelitis
Frontiers in Cellular and Infection Microbiology, 2020 Effective management of infectious osteomyelitis relies on timely microorganism identification and appropriate antibiotic therapy. Extracellular vesicles (EVs) carry protein and genetic information accumulated rapidly in the circulation upon infection ...
Songyun Deng +14 more
doaj +1 more source