Results 41 to 50 of about 87,840 (204)

Longitudinal measurement of serum cartilage oligomeric matrix protein can detect the progression of cartilage degeneration in anterior cruciate ligament reconstruction patients

Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology
Background/objective: Cartilage oligomeric matrix protein (COMP) has utility as a diagnostic marker for osteoarthritis (OA). Our previous study revealed that the serum COMP level can be used to detect early cartilage change in non-OA patients with ...
Yohei Nishida, Yusuke Hashimoto, Kumi Orita, Kazuya Nishino, Takuya Kinoshita, Ken Iida, Hiroaki Nakamura   +6 more
doaj   +1 more source

Mechanism of YAP1 in the senescence and degeneration of endplate chondrocytes induced by intermittent cyclic mechanical tension

Journal of Orthopaedic Surgery and Research, 2023
Background This study aimed to investigate the potential mechanism of YAP1 in the senescence and degeneration of endplate chondrocytes induced by intermittent cyclic mechanical tension (ICMT).
Lei Kong, Yong-Sheng Xie, Xu-Dong Ma, Yan Huang, Xi-Fu Shang   +4 more
doaj   +1 more source

Classification of patients with knee osteoarthritis in clinical phenotypes: data from the osteoarthritis initiative [PDF]

, 2018
ObjectivesThe existence of phenotypes has been hypothesized to explain the large heterogeneity characterizing the knee osteoarthritis. In a previous systematic review of the literature, six main phenotypes were identified: Minimal Joint Disease (MJD ...
A Courties, A Courties, A Dell’Isola, A Dell’Isola, A. Dell’Isola, CD King, D Heinegård, DJ Hunter, DL Riddle, DT Felson, F Angst, F Eckstein, FW Roemer, IG Otterness, J Dekker, J Knoop, JB Driban, JFM Holla, L Sharma, LC Carlesso, M a Karsdal, M Sowers, M van der Esch, M. Steultjens, MA Karsdal, MA Karsdal, Mikko Juhani Lammi, N Bellamy, N Yoshimura, PA BERRY, PM Lewinsohn, PS McCabe, S Dahaghin, S Monira Hussain, SL Murphy, SP Messier, T Neogi, TP Andriacchi, WC Bae, WEE van Spil, Y Cruz-Almeida   +40 more
core   +4 more sources

The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis. [PDF]

, 2013
Osteoarthritis (OA) is a degenerative disease that affects various tissues surrounding joints such as articular cartilage, subchondral bone, synovial membrane, and ligaments.
Maldonado, Maricela, Nam, Jin
core   +3 more sources

Correlation study between facet joint cartilage and intervertebral discs in early lumbar vertebral degeneration using T2, T2* and T1ρ mapping. [PDF]

PLoS ONE, 2017
Recent advancements in magnetic resonance imaging have allowed for the early detection of biochemical changes in intervertebral discs and articular cartilage.
Yi Zhang, Jianzhong Hu, Chunyue Duan, Ping Hu, Hongbin Lu, Xianjing Peng   +5 more
doaj   +1 more source

Common mistakes and pitfalls in magnetic resonance imaging of the knee [PDF]

, 2016
This pictorial review presents an overview of common interpretation errors and pitfalls in magnetic resonance imaging (MRI) of the knee. Instead of being exhaustive, we will emphasize those pitfalls that are most commonly encountered by young residents ...
De Vos, Nicolas, Van Dyck, Pieter, Vanhoenacker, Filip   +2 more
core   +2 more sources

Wnt signaling in cartilage development and degeneration

BMB Reports, 2008
The Wnt signaling network, which is composed of Wnt ligands, receptors, antagonists, and intracellular signaling molecules, has emerged as a powerful regulator of cell fate, proliferation, and function in multicellular organisms. Over the past two decades, the critical role of Wnt signaling in embryonic cartilage and bone development has been well ...
Jang-Soo, Chun, Hwanhee, Oh, Siyoung, Yang, Meeyoung, Park   +3 more
openaire   +3 more sources

Lipid Metabolism in Cartilage Development, Degeneration, and Regeneration

Nutrients, 2022
Lipids affect cartilage growth, injury, and regeneration in diverse ways. Diet and metabolism have become increasingly important as the prevalence of obesity has risen. Proper lipid supplementation in the diet contributes to the preservation of cartilage function, whereas excessive lipid buildup is detrimental to cartilage. Lipid metabolic pathways can
Su, Zhanpeng, Zong, Zhixian, Deng, Jinxia, Huang, Jianping, Liu, Guihua, Wei, Bo, Cui, Liao, Li, Gang, Zhong, Huan, Lin, Sien   +9 more
openaire   +3 more sources

Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis

eLife
This study aimed to investigate the glycan structural changes that occur before histological degeneration in osteoarthritis (OA) and to determine the mechanism by which these glycan conformational changes affect cartilage degeneration.
Kentaro Homan, Tomohiro Onodera, Hisatoshi Hanamatsu, Jun-ichi Furukawa, Daisuke Momma, Masatake Matsuoka, Norimasa Iwasaki   +6 more
doaj   +1 more source

An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss

Frontiers in Bioengineering and Biotechnology, 2021
Injurious mechanical loading of articular cartilage and associated lesions compromise the mechanical and structural integrity of joints and contribute to the onset and progression of cartilage degeneration leading to osteoarthritis (OA).
Seyed Ali Elahi, Seyed Ali Elahi, Petri Tanska, Rami K. Korhonen, Rik Lories, Nele Famaey, Ilse Jonkers, Ilse Jonkers   +7 more
doaj   +1 more source