Results 31 to 40 of about 315,650 (233)

Biomechanical assessment of extracellular matrix in native and tissue engineered cartilage across lenght scales [PDF]

, 2012
Musculoskeletal diseases (MSD) and related disorders account for the largest fraction of temporary and permanent disabilities, and are often considered to be an inevitable consequence of aging.
Loparic, Marko
core   +1 more source

Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis

eLife
This study aimed to investigate the glycan structural changes that occur before histological degeneration in osteoarthritis (OA) and to determine the mechanism by which these glycan conformational changes affect cartilage degeneration.
Kentaro Homan, Tomohiro Onodera, Hisatoshi Hanamatsu, Jun-ichi Furukawa, Daisuke Momma, Masatake Matsuoka, Norimasa Iwasaki   +6 more
doaj   +1 more source

Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage [PDF]

, 2014
Primary cilia are slender, microtubule based structures found in the majority of cell types with one cilium per cell. In articular cartilage, primary cilia are required for chondrocyte mechanotransduction and the development of healthy tissue.
Ramaswamy, G, Ramaswamy, Girish, Irianto, J, Serra, Rosa, Knight, MM, Knight, Martin M., Serra, R, Irianto, Jerome   +7 more
core   +1 more source

Association of Fibrosis in the Infrapatellar Fat Pad and Degenerative Cartilage Change of Patellofemoral Joint After Anterior Cruciate Ligament Reconstruction

Orthopaedic Journal of Sports Medicine, 2017
Purpose: The purpose of this study was to evaluate the prevalence and risk factor of cartilage degeneration of patellofemoral joint (PFJ) that was diagnosed by second look arthroscopy in the short term follow-up period.
Sang Hak Lee, Kyung Ho Yoon, Chan Il Bae
doaj   +1 more source

Correlation study between facet joint cartilage and intervertebral discs in early lumbar vertebral degeneration using T2, T2* and T1ρ mapping. [PDF]

PLoS ONE, 2017
Recent advancements in magnetic resonance imaging have allowed for the early detection of biochemical changes in intervertebral discs and articular cartilage.
Yi Zhang, Jianzhong Hu, Chunyue Duan, Ping Hu, Hongbin Lu, Xianjing Peng   +5 more
doaj   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

Advanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng, TzuChun Chung, Katpady Akhil Tantry, Siyu Wu, Jing Tian, Yunqi Cui, Lanyu Li, Yongzan Zhou, Zhilei Zhang, Zhe Su, Gaili Cao, Kun‐Wei Yeh, Ruipeng Li, Xianghui Xiao, Adam F. G. Leontowich, Yuan‐Yu Hsueh, Zhao Pan, Kam C. Tam, Badri Narayanan, Song Li, Yimin. A. Wu   +20 more
wiley   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

The clinical application value of 3.0T magnetic resonance T2 mapping imaging in evaluating the degree of acetabular cartilage degeneration in joint replacement surgery running title: MRI and acetabular cartilage degeneration

Journal of Orthopaedic Surgery and Research
Background To explore and compare the values of 3.0T magnetic resonance imaging (MRI) T2 mapping in evaluating the degree of acetabular cartilage degeneration in hip replacement surgery.
Xiang Peng, An-min Xie, Hua-gang Fan, Hong-liang Zhu, Di Yang, De-en Wan, Fei He, Chong Luo, Hao Li, Feng Shuang   +9 more
doaj   +1 more source

An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss

Frontiers in Bioengineering and Biotechnology, 2021
Injurious mechanical loading of articular cartilage and associated lesions compromise the mechanical and structural integrity of joints and contribute to the onset and progression of cartilage degeneration leading to osteoarthritis (OA).
Seyed Ali Elahi, Seyed Ali Elahi, Petri Tanska, Rami K. Korhonen, Rik Lories, Nele Famaey, Ilse Jonkers, Ilse Jonkers   +7 more
doaj   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

Advanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira, Luisa de Roy, Anna‐Lotta Feldmeier, Mubashir Ahmad, Sofia Pilão, Maria Ahrens, Anita Ignatius, Carsten Linti, Andreas Martin Seitz   +8 more
wiley   +1 more source