Visual histological grading system for the evaluation of in vitro-generated neocartilage [PDF]
, 2006 Here we present the development of a visual evaluation system for routine assessment of in vitro-engineered cartilaginous tissue. Neocartilage was produced by culturing human articular chondrocytes in pellet culture systems or in a scaffold-free ...
Barbero, Andrea +7 more
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Cartilage repair in the degenerative ageing knee: A narrative review and analysis
Acta Orthopaedica, 2016 Background and purpose — Cartilage damage can develop due to trauma, resulting in focal chondral or osteochondral defects, or as more diffuse loss of cartilage in a generalized organ disease such as osteoarthritis.
Mats Brittberg +5 more
doaj +1 more source
Cellular senescence in aging and osteoarthritis: Implications for cartilage repair
Acta Orthopaedica, 2016 — It is well accepted that age is an important contributing factor to poor cartilage repair following injury, and to the development of osteoarthritis.
Wei Seong Toh +8 more
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Challenging for cartilage repair [PDF]
BMC Sports Science, Medicine and Rehabilitation, 2009 Editorial When we look back on the past 15-year history of cartilage repair, it is clear that remarkable progress has been made in this area. There is no doubt that a lot of studies have been carried out on cartilage repair and chondrocytes since Brittebergs' report on ACI in 1994 [1].
openaire +3 more sources
Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]
, 2012 Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core +2 more sources
Expression and function of cartilage-derived pluripotent cells in joint development and repair
Stem Cell Research & Therapy, 2020 Cartilage-derived pluripotent cells reside in hyaline cartilage and fibrocartilage. These cells have the potential for multidirectional differentiation; can undergo adipogenesis, osteogenesis, and chondrogenesis; and have been classified as mesenchymal ...
Zhou Jiang +3 more
doaj +1 more source
Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model. [PDF]
, 2014 The clinical management of bone defects caused by trauma or nonunion fractures remains a challenge in orthopedic practice due to the poor integration and biocompatibility properties of the scaffold or implant material. In the current work, the osteogenic
Barrientos-Durán, Antonio +5 more
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Hybrid bioprinting of chondrogenically induced human mesenchymal stem cell spheroids [PDF]
, 2020 To date, the treatment of articular cartilage lesions remains challenging. A promising strategy for the development of new regenerative therapies is hybrid bioprinting, combining the principles of developmental biology, biomaterial science, and 3D ...
Asadian, Mahtab +8 more
core +2 more sources
Bridging Suture Repair for Acetabular Chondral Carpet Delamination
Arthroscopy Techniques, 2015 Acetabular chondral carpet delamination is a frequent finding at hip arthroscopy. The cartilage is macroscopically normal but deboned from the subchondral bone, without a disruption at the chondrolabral junction.
Mitsunori Kaya, M.D. +2 more
doaj +1 more source
The chondro-osseous continuum: is it possible to unlock the potential assigned within? [PDF]
, 2018 Endochondral ossification (EO), by which long bones of the axial skeleton form, is a tightly regulated process involving chondrocyte maturation with successive stages of proliferation, maturation, and hypertrophy, accompanied by cartilage matrix ...
Adams +79 more
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