Deer antler reserve mesenchyme cells with hyaluronan alleviates cartilage damage in a rat model
Reserve mesenchyme cells (RMCs) of deer antlers have been considered as the promising cell source for repairing injury‐induced articular cartilage or cartilage degeneration.
Boyin Jia+15 more
doaj +1 more source
Imaging of cartilage repair procedures
AbstractThe rationale for cartilage repair is to prevent precocious osteoarthritis in untreated focal cartilage injuries in the young and middle-aged population. The gamut of surgical techniques, normal postoperative radiological appearances, and possible complications have been described.
Dinshaw Pardiwala+2 more
openaire +4 more sources
Implantation of bone marrow-derived buffy coat can supplement bone marrow stimulation for articular cartilage repair [PDF]
SummaryObjectiveBone marrow stimulation (BMS) has been regarded as a first line procedure for repair of articular cartilage. However, repaired cartilage from BMS is known to be unlike that of hyaline cartilage and its inner endurance is not guaranteed ...
Choi, B.H.+5 more
core +1 more source
Lacking self-repair abilities, injuries to articular cartilage can lead to cartilage degeneration and ultimately result in osteoarthritis. Tissue engineering based on functional bioactive scaffolds are emerging as promising approaches for articular ...
Yucong Li+15 more
doaj
Biomechanics of integrative cartilage repair
Cartilage repair is required in a number of orthopaedic conditions and rheumatic diseases. From a macroscopic viewpoint, the complete repair of an articular cartilage defect requires integration of opposing cartilage surfaces or the integration of repair tissue with the surrounding host cartilage.
Robert L. Sah, Tabassum Ahsan
openaire +3 more sources
In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]
We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada+9 more
core +1 more source
Effect of transforming growth factor-ß1 (TGF-ß1) released from a scaffold on chondrogenesis in an osteochondral defect model in the rabbit [PDF]
Articular cartilage repair might be stimulated by the controlled delivery of therapeutic factors. We tested the hypotheses whether TGF-ß1 can be released from a polymeric scaffold over a prolonged period of time in vitro and whether its transplantation ...
Bezemer, Jeroen M.+7 more
core +2 more sources
The Application of Polysaccharide Biocomposites to Repair Cartilage Defects
Owing to own nature of articular cartilage, it almost has no self-healing ability once damaged. Despite lots of restore technologies having been raised in the past decades, no repair technology has smoothly substituted for damaged cartilage using ...
Feng Zhao+6 more
doaj +1 more source
Adult Prg4+ progenitors repair long-term articular cartilage wounds in vivo
The identity and origin of the stem/progenitor cells for adult joint cartilage repair remain unknown, impeding therapeutic development. Simulating the common therapeutic modality for cartilage repair in humans, i.e., full-thickness microfracture joint ...
Mei Massengale+12 more
doaj +1 more source
Atsttrin Promotes Cartilage Repair Primarily Through TNFR2-Akt Pathway
BackgroundCartilage defects account for substantial economic and humanistic burdens and pose a significant clinical problem. The efficacy of clinical approaches to cartilage repair is often inadequate, in part, owing to the restricted proliferative ...
Jianlu Wei+5 more
doaj +1 more source