Advances and Prospects in Stem Cells for Cartilage Regeneration
Stem Cells International, 2017 The histological features of cartilage call attention to the fact that cartilage has a little capacity to repair itself owing to the lack of a blood supply, nerves, or lymphangion.
Mingjie Wang +16 more
doaj +1 more source
Deer antler reserve mesenchyme cells with hyaluronan alleviates cartilage damage in a rat model
Animal Research and One Health, 2023 Reserve mesenchyme cells (RMCs) of deer antlers have been considered as the promising cell source for repairing injury‐induced articular cartilage or cartilage degeneration.
Boyin Jia +15 more
doaj +1 more source
Enhancing Stem Cell Therapy for Cartilage Repair in Osteoarthritis—A Hydrogel Focused Approach
Gels, 2021 Stem cells hold tremendous promise for the treatment of cartilage repair in osteoarthritis. In addition to their multipotency, stem cells possess immunomodulatory effects that can alleviate inflammation and enhance cartilage repair.
Yisi Liu +6 more
doaj +1 more source
Journal of Orthopaedic Translation, 2022 Background: Cartilage repair has been a challenge in the field of orthopaedics for decades, highlighting the significance of investigating potential therapeutic drugs.
Ziying Sun +14 more
doaj +1 more source
Mesenchymal stem cells for management of rheumatoid arthritis : immune modulation, repair or both? [PDF]
, 2018 The authors are grateful for support to their research from Arthritis Research UK (grants 19271, 19429, 19667, 20050, 20775) and the Medical Research Council (grant no.
Ansboro, Sharon +2 more
core +1 more source
The Application of Polysaccharide Biocomposites to Repair Cartilage Defects
International Journal of Polymer Science, 2014 Owing to own nature of articular cartilage, it almost has no self-healing ability once damaged. Despite lots of restore technologies having been raised in the past decades, no repair technology has smoothly substituted for damaged cartilage using ...
Feng Zhao +6 more
doaj +1 more source
The use of equine chondrogenic‐induced mesenchymal stem cells as a treatment for osteoarthritis : a randomised, double‐blinded, placebo‐controlled proof‐of‐concept study [PDF]
, 2019 Background: There is a need to improve therapies for osteoarthritis in horses. Objectives To assess the efficacy of equine allogeneic chondrogenic-induced mesenchymal stem cells combined with equine allogeneic plasma as a novel therapy for osteoarthritis
Bertone, AL +11 more
core +1 more source
Advanced Engineering Materials, EarlyView.This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov +8 more
wiley +1 more source
Adult Prg4+ progenitors repair long-term articular cartilage wounds in vivo
JCI Insight, 2023 The identity and origin of the stem/progenitor cells for adult joint cartilage repair remain unknown, impeding therapeutic development. Simulating the common therapeutic modality for cartilage repair in humans, i.e., full-thickness microfracture joint ...
Mei Massengale +12 more
doaj +1 more source
Atsttrin Promotes Cartilage Repair Primarily Through TNFR2-Akt Pathway
Frontiers in Cell and Developmental Biology, 2020 BackgroundCartilage defects account for substantial economic and humanistic burdens and pose a significant clinical problem. The efficacy of clinical approaches to cartilage repair is often inadequate, in part, owing to the restricted proliferative ...
Jianlu Wei +5 more
doaj +1 more source