Results 41 to 50 of about 200,296 (309)
, 2023 Introduction: Genome editing by CRISPR-Cas9 approaches offers promise for introducing or correcting disease-associated mutations for research and clinical applications.
Nick Strelchenko (14392203) +6 more
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, 2023 Introduction: Genome editing by CRISPR-Cas9 approaches offers promise for introducing or correcting disease-associated mutations for research and clinical applications.
Nick Strelchenko (14392203) +6 more
core +1 more source
P1 Bacteriophage-Enabled Delivery of CRISPR-Cas9 Antimicrobial Activity Against Shigella flexneri [PDF]
, 2023 The discovery of clustered, regularly interspaced, short palindromic repeats (CRISPR) and the Cas9 RNA-guided nuclease provides unprecedented opportunities to selectively kill specific populations or species of bacteria.
Serge Mostowy +7 more
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Generation of ADCK1 knock-out cells by CRISPR/Cas9 [PDF]
, 2022 openIntroduzione Il sistema CRISPR-Cas9 è una tecnica di editing genetico che si basa sull’utilizzo di una guida a singolo filamento di RNA (single-guide RNA, sgRNA) specifica, che guida l’endonucleasi Cas9 verso una regione di DNA target affinche ...
ZAMPIERI, SARA
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, 2023 Introduction: Genome editing by CRISPR-Cas9 approaches offers promise for introducing or correcting disease-associated mutations for research and clinical applications.
Nick Strelchenko (14392203) +6 more
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Epigenetic switch reveals CRISPR/Cas9 response to cytosine methylation in plants: Comment [PDF]
, 2022 Commentary on Přibylová et al. (2022). 235 p 2285-2299 Genome editing techniques, such as the CRISPR/Cas9 system, offer a game-changing opportunity for crop improvement by enabling precise modifications to be made at targeted genomic loci.
Kaur, N., Halford, N. G., Raffan, S.
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Molecular Therapy: Nucleic Acids, 2022 The CRISPR-Cas9 system has emerged as a powerful and efficient tool for genome editing. An important drawback of the CRISPR-Cas9 system is the constitutive endonuclease activity when Cas9 endonuclease and its sgRNA are co-expressed.
Seung Bum Park +8 more
doaj +1 more source
Table_1_Quality Control Strategy for CRISPR-Cas9-Based Gene Editing Complicated by a Pseudogene.docx
, 2020 CRISPR-Cas9 mediated gene editing in induced pluripotent stem cells became an efficient tool to investigate biological mechanisms underlying genetic-driven diseases while accounting for the respective genetic background.
Zoé Hanss (8267268) +4 more
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, 2023 Introduction: Genome editing by CRISPR-Cas9 approaches offers promise for introducing or correcting disease-associated mutations for research and clinical applications.
Nick Strelchenko (14392203) +6 more
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Cas9-mediated switching in human B cells.
, 2019 (A) Schematic depicting Cas9 variants and orientation of sgRNAs required to generate blunt, 5’, and 3’DSBs. One sgRNA and wild-type Cas9 produces a blunt DSB, while paired sgRNAs and Cas9 D10A or Cas9 N863A give rise to 5’ or 3’DSBs, respectively.
Alberto Martin (12795) +1 more
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