Results 11 to 20 of about 43,177 (231)

Casein Kinase 1: A Wnt'er of Disconnect [PDF]

Current Biology, 2002
Phosphorylation of beta-catenin, a central downstream component of the Wnt pathway, by glycogen synthase kinase 3 is essential for its targeted degradation by the proteosome. New studies show that casein kinase 1 primes beta-catenin for subsequent phophorylation by glycogen synthase kinase 3.
Polakis, Paul
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CSNK1A1 (casein kinase 1, alpha 1) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on CSNK1A1 (casein kinase 1, alpha 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Doerfel, M, Huber, O
openaire   +3 more sources

Phosphorylation of protein kinase C by casein kinase‐1 [PDF]

FEBS Letters, 1989
Because phosphorylation of protein kinase C (PKC) may provide a mechanism for regulation of this enzyme, we have examined the ability of two other kinases to phosphorylate PKC. Our results show that casein kinase 1 (CK‐1), but not casein kinase 2 (CK‐2), can phosphorylate PKC in the absence of Ca2+ and phospholipids.
Vila, Jordi, Walker, Jefrrey M., Itarte, Emilio, Weber, Michael J., Sando, Julianne J.   +4 more
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Phosphorylation and activation of p40 tyrosine kinase by casein kinase‐1

FEBS Letters, 1990
Because examination of regulatory trans‐phosphorylations can help elucidate the cellular functions of tyrosyi protein kinases, we have investigated the effects of phosphorylation by casein kinase‐1 on the activity of the p40 tyrosyi protein kinase. We find that casein kinase‐1 can phosphorylate the p40 tyrosyl kinase on serine and threonine residues ...
Vila, Jordi, Payne, D.Michael, Zioncheck, Thomas F., Harrison, Marietta L., Itarte, Emilio, Weber, Michael J.   +5 more
openaire   +3 more sources

Identification of casein kinase 1, casein kinase 2, and cAMP-dependent protein kinase-like activities in Trypanosoma evansi [PDF]

Memorias do Instituto Oswaldo Cruz, 2004
Trypanosoma evansi contains protein kinases capable of phosphorylating endogenous substrates with apparent molecular masses in the range between 20 and 205 kDa.
José Manuel Galán-Caridad, Maritza Calabokis, Graciela Uzcanga, Frank Aponte, José Bubis   +4 more
doaj   +4 more sources

Targeting Casein Kinase 1 (CK1) in Hematological Cancers. [PDF]

Int J Mol Sci, 2020
The casein kinase 1 enzymes (CK1) form a family of serine/threonine kinases with seven CK1 isoforms identified in humans. The most important substrates of CK1 kinases are proteins that act in the regulatory nodes essential for tumorigenesis of hematological malignancies. Among those, the most important are the functions of CK1s in the regulation of Wnt
Janovská P, Normant E, Miskin H, Bryja V.   +3 more
europepmc   +5 more sources

Casein kinase 1 delta (CK1delta) regulates period length of the mouse suprachiasmatic circadian clock in vitro. [PDF]

PLoS ONE, 2010
Casein kinase 1 delta (CK1delta) plays a more prominent role in the regulation of circadian cycle length than its homologue casein kinase 1 epsilon (CK1epsilon) in peripheral tissues such as liver and embryonic fibroblasts.
Jean-Pierre Etchegaray, Elizabeth A Yu, Premananda Indic, Robert Dallmann, David R Weaver   +4 more
doaj   +2 more sources

Dual Role of Calsequestrin as Substrate and Inhibitor of Casein Kinase-1 and Casein Kinase-2

Biochemical and Biophysical Research Communications, 1994
Calsequestrin from different muscle tissues and species has been phosphorylated by casein kinase-1 and casein kinase-2, in the conditions previously reported by Cala and Jones (J. Biol. Chem. 266, 391-398, 1991). Results indicates that rabbit cardiac and skeletal calsequestrin and frog skeletal calsequestrin are phosphorylated by both casein kinase-1 ...
SALVATORI, SERGIO, FURLAN S., MEGGIO, FLAVIO   +2 more
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Molecular genetic characterization of CASEIN KINASE 1-LIKE 12 in Arabidopsis [PDF]

Plant Signaling & Behavior
The CASEIN KINASE 1 (CK1) family plays diverse roles in the development, physiology, and disease in eukaryotes. In Arabidopsis thaliana, the CASEIN KINASE 1-LIKE (CKL) family has 13 members, but to date, the roles of these kinases remain largely unclear.
Adam Seluzicki, Annemarie E. Branks, Sowmya Poosapati, Joanne Chory   +3 more
doaj   +2 more sources

Functional analysis of Casein Kinase 1 in a minimal circadian system.

PLoS ONE, 2013
The Earth's rotation has driven the evolution of cellular circadian clocks to facilitate anticipation of the solar cycle. Some evidence for timekeeping mechanism conserved from early unicellular life through to modern organisms was recently identified ...
Gerben van Ooijen, Matthew Hindle, Sarah F Martin, Martin Barrios-Llerena, Frédéric Sanchez, François-Yves Bouget, John S O'Neill, Thierry Le Bihan, Andrew J Millar   +8 more
doaj   +4 more sources