Results 21 to 30 of about 43,177 (231)
Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Casein Kinase 1 (CK1) family members are serine/threonine protein kinases that are involved in many biological processes and highly conserved in eukaryotes from protozoan to humans.
Najma Rachidi +2 more
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Casein Kinase 1 Promotes Initiation of Clathrin-Mediated Endocytosis [PDF]
Developmental Cell, 2015 In budding yeast, over 60 proteins functioning in at least five modules are recruited to endocytic sites with predictable order and timing. However, how sites of clathrin-mediated endocytosis are initiated and stabilized is not well understood. Here, the casein kinase 1 (CK1) Hrr25 is shown to be an endocytic protein and to be among the earliest ...
Peng, Yutian +6 more
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Casein kinase 1 family member CSNK1E can regulate proliferation and migration in hepatocellular carcinoma [PDF]
Journal of Cancer Research and Clinical OncologyPurpose Some studies have shown that circadian rhythms are associated with the development and progression of hepatocellular carcinoma (HCC). In this study, we aimed to elucidate the characterization, prognostic significance and targeting value of ...
Jie Zhou +8 more
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Effect of all-trans retinoic acid on casein and fatty acid synthesis in MAC-T cells [PDF]
Asian-Australasian Journal of Animal Sciences, 2020 Objective Caseins and fatty acids of milk are synthesized and secreted by the epithelial cells of the mammary gland. All-trans retinoic acid (ATRA), an active metabolite of vitamin A, has been shown to promote mammary development.
Xian-Dong Liao +6 more
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Ribofuranosyl‐benzimidazole derivatives as inhibitors of casein kinase‐2 and casein kinase‐1 [PDF]
European Journal of Biochemistry, 1990 5,6‐Dichloro‐1‐(β‐d‐ribofuranosyl)benzimidazole (DiCl‐RB) is a powerful inhibitor of casein kinase‐2 (CK‐2) [Zandomeni, R. et al. (1986) J. Biol. Chem. 261, 3414–3420]. Here a series of 17 analogues of DiCl‐RB has been employed for studying the specificity and the mode of action of this family of CK‐2 inhibitors.
MEGGIO, FLAVIO, Shugar D, PINNA, LORENZO
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STAR Protocols, 2023 Summary: Casein kinase 1γ is a subfamily of the casein kinase 1 family. Here, we present a protocol for gene knockout of CSNK1G3 in human cells and cloning and/or expression of CSNK1G1–3 cDNAs using a retroviral vector system.
Asako Goto, Kentaro Hanada
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Unwinding the Wnt action of casein kinase 1 [PDF]
Cell Research, 2013 The casein kinase 1 (CK1) family, a major intracellular serine/threonine kinase, is implicated in multiple pathways; however, understanding its regulation has proven challenging. A recent study published in Science identifying allosteric activation of CK1 by the DEAD-box RNA helicase DDX3 expands our understanding of the control of this abundant kinase
Daniel G R, Yim, David M, Virshup
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eLife, 2020 Casein kinases are a large family of intracellular serine/threonine kinases that control a variety of cellular signaling functions. Here we report that a member of casein kinase 1 family, casein kinase 1G2, CSNK1G2, binds and inhibits the activation of ...
Dianrong Li +9 more
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The flaviviral methyltransferase is a substrate of Casein Kinase 1 [PDF]
Virus Research, 2009 Serine/Threonine phosphorylation of the nonstructural protein 5 (NS5) is a conserved feature of flaviviruses, but the identity and function(s) of the responsible kinase(s) remain unknown. Serine 56 in the methyltransferase domain of NS5 can be phosphorylated intracellularly, is conserved in all flaviviruses, and is a critical residue in the catalytic ...
Dipankar, Bhattacharya +2 more
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Malaria Parasite-Infected Erythrocytes Secrete PfCK1, the Plasmodium Homologue of the Pleiotropic Protein Kinase Casein Kinase 1. [PDF]
PLoS ONE, 2015 Casein kinase 1 (CK1) is a pleiotropic protein kinase implicated in several fundamental processes of eukaryotic cell biology. Plasmodium falciparum encodes a single CK1 isoform, PfCK1, that is expressed at all stages of the parasite's life cycle. We have
Dominique Dorin-Semblat +6 more
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