Results 41 to 50 of about 34,988 (231)
Relationship Between Casein Kinase I Isoforms and a Neurofilament‐Associated Kinase [PDF]
Journal of Neurochemistry, 1999 Abstract : Purified neurofilaments (NFs) contain an associated kinase (NFAK) activity that phosphorylates selectively a subset of sites in the tail of NF‐M and has properties consistent with casein kinase I (CKI). Because CKI consists of a family of as many as seven genes (α, β, γ1‐3, δ, and ε), we investigated the extent to which different CKI ...
Z, Fu, C L, Green, G S, Bennett
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Stimulation of Erythrocyte Cell Membrane Scrambling by Quinine
Cellular Physiology and Biochemistry, 2016 Background/Aims: The analkaloid drug quinine is utilized mainly for the chemoprophylaxis of malaria. The multiple side effects of quinine include hemolytic anemia and hemolytic uremic syndrome, disorders involving suicidal erythrocyte death or eryptosis,
Morena Mischitelli +4 more
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Regulation of hepatitis C virion production via phosphorylation of the NS5A protein. [PDF]
PLoS Pathogens, 2008 Hepatitis C virus (HCV) is a significant pathogen, infecting some 170 million people worldwide. Persistent virus infection often leads to cirrhosis and liver cancer.
Timothy L Tellinghuisen +2 more
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Casein Kinase I: From Obscurity to Center Stage [PDF]
IUBMB Life, 2001 AbstractThe casein kinase I (CKI) family of protein kinases is a group of highly related, ubiquitously expressed serine/threonine kinases found in all eukaryotic organisms from protozoa to man. Recent advances in diverse fields, including developmental biology and chronobiology, have elucidated roles for CKI in regulating critical processes such as Wnt
E, Vielhaber, D M, Virshup
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An in vitro ES cell-based clock recapitulation assay model identifies CK2α as an endogenous clock regulator. [PDF]
PLoS ONE, 2013 We previously reported emergence and disappearance of circadian molecular oscillations during differentiation of mouse embryonic stem (ES) cells and reprogramming of differentiated cells, respectively.
Yasuhiro Umemura +10 more
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Casein kinase I-dependent phosphorylation and stability of the yeast multidrug transporter Pdr5p.
, 1999 The pleiotropic drug resistance protein, Pdr5p, is an ATP-binding cassette transporter of the plasma membrane of Saccharomyces cerevisiae. Overexpression of Pdr5p results in increased cell resistance to a variety of cytotoxic compounds, a phenotype ...
Ghislain, Michel +2 more
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Isolation and characterization of a Type II casein kinase (‘casein kinase‐TS’) from Saccharomyces cerevisiae [PDF]
FEBS Letters, 1982 Among the several classes of protein kinases described up to now the so called ‘casein kinases’ are characterized by their insensitivity to any of the known effecters of other protein kinases, like cyclic nucleotides, Ca* + , calmodulin and phospholipids and by their remarkable activity in vitro toward casein and phosvitin but not toward histones and ...
RIGOBELLO, MARIA PIA +3 more
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Spermine Effect On the Binding of Casein Kinase-I To the Rat-liver Mitochondrial Structures
, 1994 The results indicated here, together with those previously reported, show that spermine, ubiquitous polyamine, while promoting the transmembrane translocation of casein kinase II (CKII) across the outer membrane to more internal compartments of rat liver
CLARI, GIULIO +5 more
core +1 more source
PLoS ONE, 2010 Predicting off-targets by computational methods is getting increasing importance in early drug discovery stages. We herewith present a computational method based on binding site three-dimensional comparisons, which prompted us to investigate the cross ...
Enrico Defranchi +5 more
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Activating PER repressor through a DBT-directed phosphorylation switch. [PDF]
PLoS Biology, 2008 Protein phosphorylation plays an essential role in the generation of circadian rhythms, regulating the stability, activity, and subcellular localization of certain proteins that constitute the biological clock. This study examines the role of the protein
Saul Kivimäe +2 more
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