Results 271 to 280 of about 12,127,416 (284)

Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis

Nature Structural & Molecular Biology, 2023
Yanjie Hou, H. Zeng, Zilin Li, N. Feng, Fanyi Meng, Yue Xu, Lin Li, Feng Shao, Jingjin Ding   +8 more
semanticscholar   +1 more source

Galectin-3 Mediates Endotoxin Internalization and Caspase-4/11 Activation in Tubular Epithelials and Macrophages During Sepsis and Sepsis-Associated Acute Kidney Injury

Inflammation, 2023
Fengyun Wang, Junwei Ye, Weiwei Zhu, Ruiqi Ge, Chang Hu, Yaoyao Qian, Yiming Li, Zhiyong Peng   +7 more
semanticscholar   +1 more source

Die Rolle der Caspase-4 und -5 in renalen Schädigungsmodellen

2021
Hintergrund und Ziele: Die murine Caspase-11 und ihre humanen Gegenstücke, Caspase-4 und -5, sind bei Entzündungsreaktionen an der Regulation von Zelluntergang und damit verbunden an der Freisetzung von Interleukin-1a beteiligt. Während die Aktivierung der Caspasen durch zytosolisches Lipopolysaccharid sehr gut untersucht ist, existieren bislang nur ...
openaire   +1 more source

Citric acid of ovarian cancer metabolite induces pyroptosis via the caspase‐4/TXNIP‐NLRP3‐GSDMD pathway in ovarian cancer

The FASEB Journal, 2022
Xiaogang Wang, Yuxin Yin, W. Qian, C. Peng, S. Shen, Tingting Wang, Shuli Zhao   +6 more
semanticscholar   +1 more source

TET2 inhibits tumorigenesis of breast cancer cells by regulating caspase-4.

Scientific reports, 2019
Epigenetic regulators have been shown to influence breast cancer progression. However, the detailed mechanism by which TET2 plays the suppressive role in tumorigenesis remains not completely understood. We employed RT-qPCR and westernblot to examine genes expression.
Xuguo, Zhu, Shuangqi, Li
openaire   +1 more source

Abstract 4132409: Caspase-4/11 promotes a high-fat diet and chronic kidney disease-accelerated vascular inflammation via caspase-4/11-IL-1b two-tier trained immunity

Circulation
Introduction: Chronic kidney disease (CKD) is a common inflammatory disease affecting >15% of the adult population and 50% of all patients with advanced/end stages (4 to 5) of CKD have cardiovascular disease. Research Questions: How multiple disease risk factors interplay to ...
Yifan Lu, Yu Sun, Fatma Saaoud, Ying Shao, keman xu, Xiao-feng Yang   +5 more
openaire   +1 more source

Caspase-4 and Caspase-5

2013
Junjun Gao, James A. Wells
openaire   +1 more source

Citrus-caspase-4-serotonin axis: Aurantii Fructus rapidly reverses chronic-stress-induced despair via suppression of hippocampal caspase-4.

Journal of Ethnopharmacology
Chao Lu, Ziwei Gao, Zixuan Wei, Yaping Zhu, Mengqi Shao, Yiran Jiang, Lei Wu   +6 more
semanticscholar   +1 more source

Caspase 4

2006
openaire   +1 more source

Caspase-4

2009
openaire   +1 more source