Results 151 to 160 of about 262,302 (283)

Data in the activities of caspases and the levels of reactive oxygen species and cytochrome c in the •OH-induced fish erythrocytes treated with alanine, citrulline, proline and their combination

Data in Brief, 2016
The present study explored the effects of alanine (Ala), citrulline (Cit), proline (Pro) and their combination (Ala10Pro4Cit1) on the activities of caspases and levels of reactive oxygen species (ROS) and cytochrome c in hydroxyl radicals (•OH)-induced ...
Huatao Li, Weidan Jiang, Yang Liu, Jun Jiang, Yongan Zhang, Pei Wu, Juan Zhao, Xudong Duan, Xiaoqiu Zhou, Lin Feng   +9 more
doaj  

Binding and Kinetic Analysis of Human Protein Phosphatase PP2A Interactions with Caspase 9 Protein and the Interfering Peptide C9h. [PDF]

Pharmaceutics, 2022
Dorgham K, Murail S, Tuffery P, Savier E, Bravo J, Rebollo A.   +5 more
europepmc   +1 more source

PRMT5 Inhibitor Synergizes with Chemotherapy to Induce Resembling Mismatch Repair Deficiency and Enhance Anti‐TIGIT Therapy in Microsatellite‐Stable Colorectal Cancer

Advanced Science, EarlyView.
Microsatellite‐stable (MSS) colorectal cancer (CRC) resists immunotherapy. PRMT5 inhibition enhances CPT‐11 sensitivity, inducing a PMS2‐deficient‐like state and cytosolic dsDNA release, which activates the cGAS‐STING pathway to promote anti‐tumor immunity. However, this combination therapy upregulates TIGIT expression on CD8+ T cells, and the addition
Jiang Zhu, Shenao Fu, Xi Zou, Hanjiang Zeng, Guangzu Cui, Yinghui Peng, Diya Tang, Fan Zhang, Hong Shen, Shan Zeng, Ying Han   +10 more
wiley   +1 more source

SRp30a (ASF/SF2) regulates the alternative splicing of caspase-9 pre-mRNA and is required for ceramide-responsiveness

Journal of Lipid Research, 2006
Two splice variants are derived from the caspase-9 gene, proapoptotic caspase-9a and antiapoptotic caspase-9b, by either the inclusion or exclusion of an exon 3, 4, 5, and 6 cassette.
Autumn Massiello, Charles E. Chalfant
doaj  

Targeted biallelic integration of an inducible Caspase 9 suicide gene in iPSCs for safer therapies. [PDF]

Mol Ther Methods Clin Dev, 2022
Wunderlich S, Haase A, Merkert S, Jahn K, Deest M, Frieling H, Glage S, Korte W, Martens A, Kirschning A, Zeug A, Ponimaskin E, Göhring G, Ackermann M, Lachmann N, Moritz T, Zweigerdt R, Martin U.   +17 more
europepmc   +1 more source

PMA induces apoptosis in the SNU-C4 colon cancer cells through caspase-9 independently of caspase-3 and -8

, 2000
Shaun G. Weller, Robert C. Penington, William E. Karnes   +2 more
openalex   +1 more source

Oxidative stress and increased levels of apoptosis (Cytochrome C, Caspase 3 and 9) in patients with male-factor infertility. [PDF]

, 2001
X Wang, Rakesh Sharma, Pavithra Ranganathan, A.J. Thomas, Tommaso Falcone, Ashok Agarwal   +5 more
openalex   +1 more source

Pia Mater‐Penetrable Lipopolymer Nanoparticles for Gliocyte‐Targeted IL‐10 mRNA Therapy Alleviate Paclitaxel‐Induced Peripheral Neuropathy

Advanced Science, EarlyView.
The P6CIT lipopolymer demonstrates superior transfection efficacy in the spinal cord and DRG, as well as enhanced penetration of the pia mater compared to the MC3 ionizable lipid. Intrathecal delivery of P6CIT LPNPs enables effective transfection in the gliocytes in the spinal cord and DRG.
Xinrou Lin, Lingyu Wei, Xiangpen Li, Ling Zeng, Yingsen Tang, Hongjin Wang, Hengjian Lu, Chenguang Li, Hongxuan Wang, Jinjin Chen, Ying Peng   +10 more
wiley   +1 more source

Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy. [PDF]

Acta Pharmacol Sin, 2023
Li L, Song JJ, Zhang MX, Zhang HW, Zhu HY, Guo W, Pan CL, Liu X, Xu L, Zhang ZY.   +9 more
europepmc   +1 more source

Erratum: correction: A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis [PDF]

, 2001
Srinivasa M. Srinivasula, R.P. Hegde, Ayman Saleh, Pinaki Datta, Eric N. Shiozaki, Jijie Chai, Ryung‐Ah Lee, Paul D. Robbins, Teresa Fernandes‐Alnemri, Yigong Shi, Emad S. Alnemri   +10 more
openalex   +1 more source