Results 151 to 160 of about 274,264 (283)

PMA induces apoptosis in the SNU-C4 colon cancer cells through caspase-9 independently of caspase-3 and -8

, 2000
Shaun G. Weller, Robert C. Penington, William E. Karnes   +2 more
openalex   +1 more source

Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction [PDF]

, 2001
Yeo-Jin Chae, Ho‐Shik Kim, Hyangshuk Rhim, Bo‐Eun Kim, Seong‐Whan Jeong, In‐Kyung Kim   +5 more
openalex   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Linalool attenuated ischemic injury in PC12 cells through inhibition of caspase-3 and caspase-9 during apoptosis. [PDF]

Food Sci Nutr, 2023
Hosseini A, Pourheidar E, Rajabian A, Asadpour E, Hosseinzadeh H, Sadeghnia HR.   +5 more
europepmc   +1 more source

Erratum: correction: A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis [PDF]

, 2001
Srinivasa M. Srinivasula, R.P. Hegde, Ayman Saleh, Pinaki Datta, Eric N. Shiozaki, Jijie Chai, Ryung‐Ah Lee, Paul D. Robbins, Teresa Fernandes‐Alnemri, Yigong Shi, Emad S. Alnemri   +10 more
openalex   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

Binding and Kinetic Analysis of Human Protein Phosphatase PP2A Interactions with Caspase 9 Protein and the Interfering Peptide C9h. [PDF]

Pharmaceutics, 2022
Dorgham K, Murail S, Tuffery P, Savier E, Bravo J, Rebollo A.   +5 more
europepmc   +1 more source

HIV-1 Vpr Induces Apoptosis through Caspase 9 in T Cells and Peripheral Blood Mononuclear Cells [PDF]

, 2002
Kar Muthumani, Daniel S. Hwang, Brijal Desai, Donghui Zhang, Nathanael N. Dayes, Douglas R. Green, David B. Weiner   +6 more
openalex   +1 more source

Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5

Advanced Science, EarlyView.
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao, Yuan Fei Li, Fu Kang Yuan, Meng Lu Zhao, Ya Wen Han, Jia Xin Wang, Qi Yang, Han Ying Ye, Yu Cheng Lu, Shao Chin Lee   +9 more
wiley   +1 more source

Targeted biallelic integration of an inducible Caspase 9 suicide gene in iPSCs for safer therapies. [PDF]

Mol Ther Methods Clin Dev, 2022
Wunderlich S, Haase A, Merkert S, Jahn K, Deest M, Frieling H, Glage S, Korte W, Martens A, Kirschning A, Zeug A, Ponimaskin E, Göhring G, Ackermann M, Lachmann N, Moritz T, Zweigerdt R, Martin U.   +17 more
europepmc   +1 more source