Results 231 to 240 of about 578,436 (295)

Probiotic <i>Lactiplantibacillus plantarum</i> WB4404 and WB4503 from Kimchi Induce Apoptosis in Human Colorectal Cancer Cells <i>In Vitro</i>. [PDF]

J Microbiol Biotechnol
Lee ES, Yoon HJ, Min SJ, Park JY, Kim SB, Lee NK, Paik HD.   +6 more
europepmc   +1 more source

Predominance of Ferroptotic Cell Death Mechanisms in Substantia Nigra Neurodegeneration in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng, Anusha Jayaraman, Richard Reynolds, Jia Nee Foo   +3 more
wiley   +1 more source

Natural product-induced apoptosis in oral squamous cell carcinoma via targeting mitochondrial multifunctionality. [PDF]

Front Oncol
Zhou Q, Wu Z, Chen M, He H, Liu P, Xu M, Xu Q, Yan J.   +7 more
europepmc   +1 more source

The Far Side of Carboranes: Anticancer Active Monocations and Ambiently Stable Dications

Angewandte Chemie, EarlyView.
This work describes the synthesis of bench‐stable dicationic carboranes. Their enhanced electrophilicity is documented by opening the clusters with weak nucleophiles or dihydrogen. The surprising stability of positively charged carboranes in water enabled a study of their in vitro antiproliferative activity, which surpassed the effects of doxorubicin ...
Vlastimil Němec, Josef Holub, Maksim A. Samsonov, Zdeňka Růžičková, Josef Cvačka, Ján Vančo, Zdeněk Trávníček, Jan Belza, Zdeněk Dvořák, Jan Vrána, Aleš Růžička   +10 more
wiley   +1 more source

Gasdermins against intracellular bacterial pathogens. [PDF]

Nat Microbiol
Souza FW, Liu Y, Trujillo J, Miao EA.
europepmc   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +1 more source

Caspase-3/7 deficiency results in enhanced intestinal inflammation and reduced tumorigenesis. [PDF]

Sci Adv
Xie W, Wyckaert L, Vadi M, Verstraeten B, Divert T, Haerinck J, De Rycke R, Baeke F, Lamkanfi M, Berx G, Wahida A, Vandenabeele P.   +11 more
europepmc   +1 more source

Molybdenum and cadmium co-induced apoptosis and necroptosis via activating endoplasmic reticulum stress and upregulating Caspase-8 expression in duck hepatocytes. [PDF]

Poult Sci
Xiao L, Nie G, Dai X, Li S, Wang S, Le X, Ren J, Zhang C.   +7 more
europepmc   +1 more source

Decreased Corneal Endothelial Cell Apoptosis Due to U/S Power Injury With Limbal Mesenchymal Stem Cell Secretome Therapy. [PDF]

Stem Cells Int
Hermawan D, Sudiana IK, Rantam FA, Komaratih E.   +3 more
europepmc   +1 more source

<i>Mycobacterium tuberculosis</i> Rv0927c inhibits the proliferation and promotes the intrinsic apoptosis of alveolar epithelial cells through targeting mitochondrial TUFM. [PDF]

Front Immunol
Xia A, Li X, Chen X, Quan J, Wan J, Zheng C, Xu Z, Jiao X.   +7 more
europepmc   +1 more source