Results 261 to 270 of about 24,063,457 (338)

Mesoporous Gold Nanospheres Confined Platinum Nanoclusters as Robust ROS and Oxygen Nanogenerators for NIR‐II Hyperthermia Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Mesoporous gold nanospheres confined platinum nanoclusters (MGNSs@Pt) is developed as robust hydroxyl radical and oxygen nanogenerators for multimodal therapies. Their NIR‐II LSPR property also allowed MGSNs to be ideal phototheranostic agents. The chemodynamic and photothermal therapy efficiently induced the tumor cell apoptosis, enabling the MGNSs@Pt
Fei Cun   +7 more
wiley   +1 more source

Amantadine reduces sepsis-induced brain injury via NLRP3/caspase-1 inflammasome activation. [PDF]

open access: yesIran J Basic Med Sci
Karabacak P   +7 more
europepmc   +1 more source

Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion

open access: yesCell Death and Differentiation, 2016
Stephanie A Conos   +8 more
semanticscholar   +1 more source

EBBP‐Mediated Integrated Stress Response Attenuates Anthracycline‐Induced Cardiotoxicity by Inhibiting the Ferroptosis of Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen   +9 more
wiley   +1 more source

Adipocytes Promote Cisplatin Resistance through Secreting A1BG and Regulating NAMPT/PARP1 Axis‐Mediated DNA Repair in Osteosarcoma

open access: yesAdvanced Science, EarlyView.
The proposed working model for how adipocytes participate in cisplatin resistance in osteosarcoma. The adipocytes secret A1BG and stabilize NAMPT, leading to increased NAD⁺ levels and subsequent increased PARP1‐mediated DNA repair, resulting in cisplatin resistance in osteosarcoma finally.
Yonghui Liang   +8 more
wiley   +1 more source

Caspase-1-dependent pyroptosis converts αSMA<sup>+</sup> CAFs into collagen-III<sup>high</sup> iCAFs to fuel chemoresistant cancer stem cells. [PDF]

open access: yesSci Adv
Gao H   +16 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy