Results 111 to 120 of about 390,973 (308)

Protective Effects of <em>Chlorella</em>-Derived Peptide Against UVC-Induced Cytotoxicity through Inhibition of Caspase-3 Activity and Reduction of the Expression of Phosphorylated FADD and Cleaved PARP-1 in Skin Fibroblasts

open access: yesMolecules, 2012
UVC irradiation induces oxidative stress and leads to cell death through an apoptotic pathway. This apoptosis is caused by activation of caspase-3 and formation of poly(ADP-ribose) polymerase-1 (PARP-1). In this study, the underlying mechanisms<em>
Jong Yuh Cherng, Mei Fen Shih
doaj   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova   +4 more
wiley   +1 more source

Caspase-8 and Caspase-9 Functioned Differently at Different Stages of the Cyclic Stretch-Induced Apoptosis in Human Periodontal Ligament Cells

open access: yes, 2016
BackgroundHuman periodontal ligament (PDL) cells underwent apoptosis after mechanical stretch loading. However, the exact signalling pathway remains unknown.
Chun Xu (286394)   +4 more
core   +1 more source

Caspase-8 RNA half-life and CpG positions on its promoter proximal region.

open access: yes, 2022
(A) Quantification of caspase-8 mRNA to check its half-life post transcriptional block (using Actinomycin-D) (n = 3). (B) In situ hybridization with anti-sense and sense probe of caspase-8 RNA (in vitro) [scale = 10 μm].
Akshay Hegde (13813404)   +7 more
core   +1 more source

Paeoniflorin Improves Cardiac Function and Decreases Adverse Postinfarction Left Ventricular Remodeling in a Rat Model of Acute Myocardial Infarction [Corrigendum]

open access: yesDrug Design, Development and Therapy, 2020
Chen H, Dong Y, He X, Li J, Wang J. Drug Des Devel Ther. 2018;12:823–836. The authors have advised Figure 11D on page 833 is incorrect. Due to an error at the time of figure assembly Figure 10D and Figure 11D were duplicated.
Chen H, Dong Y, He X, Li J, Wang J
doaj  

Apoptotic Effect of Coix Polysaccharides on A549 Lung Cancer Cells in Vitro

open access: yesChinese Journal of Lung Cancer, 2012
Background and objective Coix seeds are commonly used in Traditional Chinese Medicine and ingested through daily diet. The aim of this study is to analyze the apoptotic effect of coix polysaccharides on A549 cells.
Cheng LUO, Wei LIU, Xiangyi LU
doaj   +1 more source

Tracheal cryopreservation: caspase-3 immunoreactivity in tracheal epithelium and in mixed glands

open access: yesBrazilian Journal of Medical and Biological Research, 2009
Cryopreservation has an immunomodulating effect on tracheal tissue as a result of class II antigen depletion due to epithelium exfoliation. However, not all epithelium is detached.
A. Sotres-Vega   +6 more
doaj   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

Caspase-3 cleavage in M. agalactiae-infected HeLa cells.

open access: yes, 2016
The graph represents the average relative density of cleaved caspase-3 from the immunoblots of M. agalactiae-infected (+ MA) and uninfected (- MA) HeLa cells at 24 and 48 h.
Renate Rosengarten (503766)   +3 more
core   +1 more source

Miltirone induces GSDME-dependent pyroptosis in colorectal cancer by activating caspase 3

open access: yesHeliyon
Colorectal cancer (CRC) is a common and malignant tumor, ranking as the third most common cancer in men and the second most common cancer in women. Pyroptosis, a recently described programmed cell death mechanism mediated by the GSDM family, has emerged ...
Guangwei Zheng   +3 more
doaj   +1 more source

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