Results 111 to 120 of about 390,973 (308)
UVC irradiation induces oxidative stress and leads to cell death through an apoptotic pathway. This apoptosis is caused by activation of caspase-3 and formation of poly(ADP-ribose) polymerase-1 (PARP-1). In this study, the underlying mechanisms<em>
Jong Yuh Cherng, Mei Fen Shih
doaj +1 more source
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova +4 more
wiley +1 more source
BackgroundHuman periodontal ligament (PDL) cells underwent apoptosis after mechanical stretch loading. However, the exact signalling pathway remains unknown.
Chun Xu (286394) +4 more
core +1 more source
Caspase-8 RNA half-life and CpG positions on its promoter proximal region.
(A) Quantification of caspase-8 mRNA to check its half-life post transcriptional block (using Actinomycin-D) (n = 3). (B) In situ hybridization with anti-sense and sense probe of caspase-8 RNA (in vitro) [scale = 10 μm].
Akshay Hegde (13813404) +7 more
core +1 more source
Chen H, Dong Y, He X, Li J, Wang J. Drug Des Devel Ther. 2018;12:823–836. The authors have advised Figure 11D on page 833 is incorrect. Due to an error at the time of figure assembly Figure 10D and Figure 11D were duplicated.
Chen H, Dong Y, He X, Li J, Wang J
doaj
Apoptotic Effect of Coix Polysaccharides on A549 Lung Cancer Cells in Vitro
Background and objective Coix seeds are commonly used in Traditional Chinese Medicine and ingested through daily diet. The aim of this study is to analyze the apoptotic effect of coix polysaccharides on A549 cells.
Cheng LUO, Wei LIU, Xiangyi LU
doaj +1 more source
Tracheal cryopreservation: caspase-3 immunoreactivity in tracheal epithelium and in mixed glands
Cryopreservation has an immunomodulating effect on tracheal tissue as a result of class II antigen depletion due to epithelium exfoliation. However, not all epithelium is detached.
A. Sotres-Vega +6 more
doaj +1 more source
Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal +3 more
wiley +1 more source
Caspase-3 cleavage in M. agalactiae-infected HeLa cells.
The graph represents the average relative density of cleaved caspase-3 from the immunoblots of M. agalactiae-infected (+ MA) and uninfected (- MA) HeLa cells at 24 and 48 h.
Renate Rosengarten (503766) +3 more
core +1 more source
Miltirone induces GSDME-dependent pyroptosis in colorectal cancer by activating caspase 3
Colorectal cancer (CRC) is a common and malignant tumor, ranking as the third most common cancer in men and the second most common cancer in women. Pyroptosis, a recently described programmed cell death mechanism mediated by the GSDM family, has emerged ...
Guangwei Zheng +3 more
doaj +1 more source

