Results 41 to 50 of about 390,973 (308)

Overexpression of caspase-3 in hepatocellular carcinomas [PDF]

Modern Pathology, 2004
Caspase-3 is a downstream effector cysteine protease in the apoptotic pathway. It is ubiquitously expressed in normal human tissues including the liver. Overexpression and loss of expression of caspase-3 has been reported in diverse human malignancies. However, expression of caspase-3 in hepatocellular carcinoma (HCC) has not been studied.
Rajendra, Persad, Chen, Liu, Tsung-Teh, Wu, Patrick S, Houlihan, Stanley R, Hamilton, Anna M, Diehl, Asif, Rashid   +6 more
openaire   +2 more sources

Caspase-3 activity.

, 2019
Caspase-3 activity in the hippocampus (CA1, DG), medial amygdala (MA) and lateral amygdala (LA) of the different groups. Caspase-3 activity was lower in the B.
Thomas A. Tompkins (2695411), François Trudeau (6619475), Guy Rousseau (125035), Kim Gilbert (6619478), Roger Godbout (6619481), Annie Tremblay (4267930)   +5 more
core   +1 more source

Immunohistochemical Expression of Caspase 3 in Psoriasis

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2017
Psoriasis is a persistent chronic immune-mediated, relapsing, inflammatory and hyper proliferative skin disorder with genetic predisposition. Psoriasis can be considered as a T-cell mediated disease, with a complex role for a variety of cytokine interaction between keratinocytes and T-lymphocytes.
Shaimaa M.M. Bebars, Dalia Rifaat Al-Sharaky, Mohammed A. Gaber, Dina Ragab Afify   +3 more
openaire   +3 more sources

Caspase-3, Shears for Synapse Pruning [PDF]

Developmental Cell, 2014
Motor neurons regulate neuromuscular junction formation by using agrin to stimulate acetylcholine receptor clustering and using acetylcholine to disperse unnecessary receptor clusters on muscle fibers. Wang et al. (2014) now report in this issue of Developmental Cell a critical role for caspase-3 in intracellular mechanisms of acetylcholine-induced ...
Shen, Chengyong, Xiong, Wen C., Mei, Lin   +2 more
openaire   +2 more sources

Identification of caspase 3 motifs and critical aspartate residues in human Phospholipase D1b and Phopsholipase D2a [PDF]

, 2008
Stimulation of mammalian cells frequently initiates phospholipase D-catalysed hydrolysis of phosphatidylcholine in the plasma membrane to yield phosphatidic acid (PA) a novel lipid messenger.
Ladds, Graham, Aletrari, Mina-Olga, Hodgkin, Matthew N., Farquhar, Michelle J., Wright, Michelle H.   +4 more
core   +1 more source

Caspase-3/7 activity observed during KSHV infection when Bcl-xL is inhibited.

, 2023
Representative images of mock or KSHV infected TIME cells that have been treated with vehicle control or A-133 at 48 hpi. A caspase-3/7 substrate was added to all cells at the same time as vehicle control or A-133.
Michael Lagunoff (143637), Michael Lagunoff, Lyndsey N. Moore (15447690), Daniel L. Holmes (15447693), Anjali Sharma, Joselyn Landazuri Vinueza (15447696), Daniel L. Holmes, Joselyn Landazuri Vinueza, Anjali Sharma (538603), Lyndsey N. Moore   +9 more
core   +1 more source

Expression of caspase-3, caspase-9, GDF-9 and IGF-1 genes in ovine oocytes cultured with optimum and elevated doses of Amphiregulin, Neuregulin-1 and Tumour necrosis factor-α in-vitro

Indian Journal of Animal Sciences, 2022
The present study was conducted to evaluate the expression of caspase-3, caspase-9, growth differentiation factor-9 (GDF-9) and insulin growth factor-1 (IGF-1) genes in oocytes cultured in vitro with optimum and elevated doses of amphiregulin (50 ng and
RAMESH HONDARAVALLI SOMASHETTY, NANDI SUMANTA, GIRISH KUMAR VENKATESH   +2 more
doaj   +1 more source

suresh-lab/caspase-3 v1

, 2019
A non-apoptotic protective role for Caspase-3 ...
Suresh Lab
core   +1 more source

Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1 [PDF]

, 2011
IL-1b and IL-18 are proinflammatory cytokines that contribute to renal immune complex disease, but whether IL-1b and IL-18 are mediators of intrinsic glomerular inflammation is unknown.
Volker Vielhauer, Clemens D Cohen, Vielhauer, V, Lichtnekert Julia, Dan Muruve, Shrikant R. Mulay, Muruve, D, Ramanjaneyulu Allam, Maja T. Lindenmeyer, Lichtnekert, Julia, Hans-Joachim Anders, Lindenmeyer, M T, Cohen Clemens D., Kulkarni, Onkar P., Vielhauer, Volker, Muruve Dan, Kulkarni Onkar P., Maja T Lindenmeyer, Cohen, Clemens D., Ryu, Mi, Rupanagudi Khader Valli, Ryu Mi, Khader Valli Rupanagudi, Mulay Shrikant R., Ryu, M, Lindenmeyer, Maja T., Anders Hans-Joachim, Clemens D. Cohen, Cohen, C D, Onkar P Kulkarni, Shrikant R Mulay, Allam, R, Allam Ramanjaneyulu, Vielhauer Volker, Muruve, Dan, Rupanagudi, Khader Valli, Anders, Hans-Joachim, Mi Ryu, Lichtnekert, J, Mulay, Shrikant R., Allam, Ramanjaneyulu, Julia Lichtnekert, Lindenmeyer Maja T., Rupanagudi, K V, Mulay, S R, Kulkarni, O P, Anders, H J, Onkar P. Kulkarni   +47 more
core   +1 more source

Caspase-3 participates in the E10.5 lethality of RIPK1 D325A mutant mice while neither intrinsic apoptosis nor pyroptosis is required.

, 2021
(A) Western blot analysis for Apaf-1 expression in embryos of indicated genotypes. (B) IF staining of E10.5 YS of indicated genotypes with anti-PECAM (red) and anti-ASC (green) or anti-Cl.GSDMD (green) antibodies. Scale bars, 50 μm.
Ye-hsuan Sun (11338002), Lang Li (91927), Chenchen Ruan (11337999), Wenke Shi (11338005), Yingying Zhang (42910), Jiahuai Han (247944), Tao Han (22342), Wei Han (151406), Yuxia Zhang (318750), Su-qin Wu (11338008), Kai Huang (3983), Jun Liu (42548), Jing Song (188926)   +12 more
core   +1 more source