Results 251 to 260 of about 160,266 (354)

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super‐Resolution Imaging and Genome Modification

Advanced Science, EarlyView.
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge, Joseph B. Wekselblatt, Scott Elmore, Bo Wang, Tongtong Wang, Renjinming Dai, Tingting Zhang, Harsh Dave, Mohammadaref Ghaderi, Athul Raj Anilkumar, Bill Wang, Shashank R. Sirsi, Jung‐Mo Ahn, Mikhail G. Shapiro, Yuki Oka, Carlos Lois, Zhenpeng Qin   +16 more
wiley   +1 more source

Synthesis and Characterization of Graphene Oxide/Polyethylene Glycol/Folic Acid/Brucine Nanocomposites and Their Anticancer Activity on HepG2 Cells

International Journal of Nanomedicine
Ibrahim Abdel Aziz Ibrahim,1 Abdullah R Alzahrani,1 Ibrahim M Alanazi,1 Naiyer Shahzad,1 Imran Shahid,1 Alaa Hisham Falemban,1 Mohd Fahami Nur Azlina,2 Palanisamy Arulselvan3 1Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura ...
Ibrahim IAA, Alzahrani AR, Alanazi IM, Shahzad N, Shahid I, Falemban AH, Nur Azlina MF, Arulselvan P   +7 more
doaj  

Deciphering the effects of bixin on pulmonary alveolar adenocarcinoma migration and proliferation via targeting BAX/BCL-2 and Cyclin D1. [PDF]

Sci Rep
Varghese R, Ramamoorthy S.
europepmc   +1 more source

Calpain activation is upstream of caspases in radiation-induced apoptosis [PDF]

, 1998
Nigel J. Waterhouse, Debra M Finucane, Douglas R. Green, John S. Elce, Sharad Kumar, Emad S. Alnemri, Gerald Litwack, KumKum Khanna, Martin F. Lavin, Dianne Watters   +9 more
openalex   +1 more source

Robust Controlled Degradation of Enzyme Loaded PCL‐Based Fibrous Scaffolds Toward Scarless Skin Tissue Regeneration

Advanced Science, EarlyView.
A novel biodegradable wound dressing (E‐PCLs) based on polycaprolactone (PCL) and an enzyme complex (RHP‐BCL) is developed using a fiber microfluidic electrospinning technique. The dressing achieves complete degradation within 14 days, eliminates microplastic residues, and promotes scar‐free healing (99% in 21 days).
Lingling Fan, Weiliang Dong, Jianqi Lu, Yujia Peng, Bin Xie, Ping Wei, Min Jiang, Su Chen   +7 more
wiley   +1 more source

Executioner caspases degrade essential mediators of pathogen-host interactions to inhibit growth of intracellular Listeria monocytogenes. [PDF]

Cell Death Dis
Lavergne M, Schaerer R, De Grandis S, Bouheraoua S, Adenuga O, Muralt T, Schaerer T, Chèvre L, Failla A, Matthey P, Stumpe M, Kressler D, Mantel PY, Walch M.   +13 more
europepmc   +1 more source

Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death [PDF]

, 1998
Gustavo P. Amarante-Mendes, Deborah Finucane, Séamus J. Martin, Thomas G. Cotter, Guy S. Salvesen, Douglas R. Green   +5 more
openalex   +1 more source

Neoadjuvant Chemotherapy With Cisplatin Up‐Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14‐Mediated EMT Activation

Advanced Science, EarlyView.
Oral squamous cell carcinoma cells exhibit upregulated expression of GSDMD upon exposure to low‐dose cisplatin chemotherapy, which subsequently interacts with MMP14 through its N‐terminal domain, activating the epithelial‒mesenchymal transition (EMT) process and promoting the lymph node metastasis of oral squamous cell carcinoma.
Zixian Huang, Qiming Jiang, Qianyu Zhang, Nan Lu, Xi Rui, Rui Chen, Yan Wang, Yuepeng Wang, Xiaoding Xu, Zhiquan Huang   +9 more
wiley   +1 more source

A new perspective on apoptosis: Its impact on meat and organoleptic quality in different animals. [PDF]

Food Chem X
Lee B, Choi YM.
europepmc   +1 more source

Biomedical Applications of Gadolinium‐Containing Biomaterials: Not Only MRI Contrast Agent

Advanced Science, EarlyView.
This paper summarizes the latest applications and potential mechanisms of the rare earth element gadolinium in biomedical fields, in addition to its traditional application as an MRI contrast agent, including osteogenesis, antimicrobial, antitumor, bioimaging, bioprobes, and so on.
Xingtong Pan, Menglong Hu, Likun Wu, Erfan Wei, Qiyue Zhu, Letian Lv, Xiuyun Xv, Xinyi Dong, Hao Liu, Yunsong Liu   +9 more
wiley   +1 more source